Test Price
2,800 AED✅ Home Collection Available
CROCC Gene Sequencing Test in UAE | 2800 AED | DHA Licensed Diagnostics
Executive Summary & Core Metrics
Executive Summary: Advanced genetic test utilising Next-Generation Sequencing (NGS) for definitive diagnosis of neurodevelopmental disorders associated with the CROCC gene. Achieves 99.9% diagnostic sensitivity through ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139). Fully compliant with Dubai Health Authority (DHA) regulatory frameworks and UAE Federal Data Protection Legislation.
- ✔ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- ✔ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- ✔ Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation with a DHA-licensed genetic counsellor.
- ✔ Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The CROCC Gene Sequencing test employs Next-Generation Sequencing (NGS) to detect pathogenic variants in the CROCC gene associated with neurodevelopmental disorders. This assay provides a definitive molecular diagnosis, enabling precise clinical management, prognostic clarity, and informed genetic counselling for affected families.
| Feature | Our CROCC NGS Test | Closest Alternative (Single-Gene Sanger) |
|---|---|---|
| Precision | >99.9% analytical sensitivity, full gene coverage including intronic regions | ~95% per amplicon, limited to exonic boundaries |
| Method | NGS with copy number variant (CNV) analysis and structural variant detection | Sanger sequencing (no CNV or structural variant detection) |
| Turnaround Time | 3–4 weeks (expedited options available) | 4–6 weeks |
| Regulatory Compliance | DHA Guidelines, UAE PDPL, Federal Law No. 2 of 2019 | Variable |
Physician Insight & Safety Protocols
From Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403: “In my clinical practice, families often endure years of uncertainty when seeking answers for unexplained neurodevelopmental delays. This targeted NGS test for CROCC provides a definitive molecular answer in a matter of weeks, not months. However, I must emphasise that genetic test results must always be interpreted alongside comprehensive clinical evaluation, detailed family history, and multidisciplinary assessment. A genetic diagnosis is a powerful tool, but it is the beginning of a care pathway, not the endpoint.”
⚠️ Pre-Test Advisory
Do not discontinue any prescribed medication without consulting your physician. Abrupt cessation of neurological therapies may worsen symptoms and compromise clinical stability.
Exclusion Criteria & Safety Red Flags
- Exclusion Criteria: Haemodynamic instability, inability to provide informed consent, or invalid sample without repeat collection option.
- Emergency Red Flags: Sudden loss of consciousness, acute-onset seizures, or new paralysis — seek immediate emergency care; do not wait for test results.
- Minors: Genetic testing of minors requires legal guardian consent and pre-test counselling as mandated by UAE Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What is the CROCC gene test and why is it recommended?
Overview: This test sequences the CROCC gene using NGS to detect mutations linked to neurodevelopmental disorders including autism spectrum disorder and global developmental delay, providing a precise genetic diagnosis.
It is recommended when a child presents with global developmental delay, intellectual disability, or autism spectrum features where a genetic aetiology is suspected. The result guides therapeutic planning, prognostic counselling, and informed family planning decisions.
2. How is the sample collected and what preparation is required?
Overview: A certified phlebotomist collects a peripheral whole blood sample during a scheduled home visit. No fasting is required, and all standard medications may be continued unless your physician advises otherwise.
You will receive a pre-test genetic counselling session to construct a three-generation pedigree and review clinical history. The sample is transported under temperature-controlled cold chain to our ISO-certified laboratory for processing.
3. How long do results take and how will I receive them?
Overview: Results are finalised within 3 to 4 weeks and delivered via a secure patient portal with a scheduled telephonic clinical interpretation session.
Your report is reviewed by a Consultant Medical Geneticist and includes variant classification according to DHA standards. A post-test counselling appointment is arranged automatically; our support line is available for urgent queries.
4. What are the benefits and limitations of this test?
Overview: Benefits include definitive molecular diagnosis, avoidance of unnecessary investigations, and targeted management planning. Limitations include detection of variants of uncertain significance (VUS) and the possibility of identifying incidental findings requiring further evaluation.
All VUS results are reviewed by a multidisciplinary team and may require segregation studies in family members. Pre-test counselling addresses these scenarios so families can make an informed decision.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance & Data Protection Framework: DNA Labs UAE operates under DHA Facility License Number 1143 and adheres to the highest standards of patient data confidentiality and clinical safety. All genetic data is processed in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent protocols and medical liability safeguards are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. Our ISO 9001:2015 certified quality management system (Cert: INT/EGQ/2509DA/3139) ensures end-to-end traceability, data integrity, and secure handling of all genetic information.
Clinical & Logistical Metadata
| Test Name | CROCC Gene Sequencing Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks (expedited options available) |
| Sample Type / Matrix | Peripheral Whole Blood (3–5 mL in EDTA tube) — VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM) |
| Methodology Used | Next-Generation Sequencing (NGS) with CNV and structural variant analysis |
| ICD-10-CM Code | F88, Z13.39 |
| LOINC Code | 55233-1 |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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