Test Price
2,800 AED✅ Home Collection Available
CORO1A Gene (Immunodeficiency Type 8) Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
This advanced single-gene sequencing assay provides definitive molecular diagnosis of CORO1A-related severe combined immunodeficiency type 8. The test delivers 99.9% diagnostic sensitivity through ISO-accredited next-generation sequencing with orthogonal Sanger confirmation, enabling precise immunomodulatory treatment planning and genetic counseling for affected patients and their families.
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- ✓ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection daily from 8 AM to 11 PM.
- ✓ Clinical Guidance: Telephonic post-test clinical interpretation by a DHA-licensed Consultant Medical Geneticist.
- ✓ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The CORO1A Gene (Immunodeficiency Type 8) Genetic Test is a definitive single-gene sequencing assay utilising targeted next-generation sequencing of the complete CORO1A coding region and intron-exon boundaries. The test is indicated for patients with clinical suspicion of inherited immune dysregulation presenting with recurrent skin infections, severe viral susceptibilities, or combined immunodeficiency. All pathogenic and likely pathogenic variants are confirmed via Sanger sequencing prior to clinical reporting.
| Feature | Our Test (Targeted NGS) | Whole Exome Sequencing (Closest Alternative) |
|---|---|---|
| Diagnostic Precision | >99.9% sensitivity for coding variants | Variable; may miss deep intronic mutations |
| Methodology | NGS with Sanger confirmation of reported variants | Exome capture + NGS; often requires orthogonal validation |
| Turnaround Time | 3–4 Weeks | 6–12 Weeks |
| Cost in UAE | 2,800 AED | 5,000–8,000 AED |
Physician Insight & Safety Protocols
“CORO1A deficiency often presents with recalcitrant cutaneous infections and warts that fail standard dermatological therapy. Targeted NGS sequencing provides the molecular confirmation needed to differentiate this rare immunodeficiency from more common skin conditions. A positive result guides immunoglobulin replacement, antimicrobial prophylaxis, and consideration of haematopoietic stem cell transplantation. Always correlate genetic findings with immunological phenotyping before initiating therapy.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Clinical Advisory
This test provides diagnostic information only. Do not alter or discontinue any prescribed therapy without explicit instruction from your treating physician. Genetic test results should be interpreted within the full clinical context including immunological laboratory parameters and family history.
Exclusion Criteria & Emergency Indications
- This test is not suitable for individuals with acute febrile illness or active systemic infection that may delay sample collection.
- Seek emergency care immediately if you develop signs of severe sepsis (high fever, confusion, difficulty breathing) or uncontrolled bleeding before arranging the test.
- Patients on systemic steroids or biologics should discuss testing timing with their physician to avoid potential interference with immune cell counts.
Patient FAQ & Clinical Guidance
1. What is the CORO1A Gene (Immunodeficiency Type 8) Genetic Test?
This test sequences the complete CORO1A gene to detect mutations causing severe combined immunodeficiency with dermatological manifestations. It is indicated for patients with recurrent bacterial or viral skin infections, persistent warts, or family history suggestive of early-onset immune defects. A positive result enables precise diagnosis, genetic counseling, and tailored antimicrobial prophylaxis.
2. How is the sample collected and what are the pre-test requirements?
Sample collection is performed via standard peripheral venipuncture by our certified mobile phlebotomist at your home between 8 AM and 11 PM. No fasting is required, but a completed clinical history form and a three-generation pedigree must be provided. Pre-test genetic counseling is mandatory to ensure informed consent and appropriate family screening.
3. How long does it take to get results and how will I receive them?
Results are typically ready within 3 to 4 weeks and are delivered via an encrypted, HIPAA-equivalent patient portal. A post-test teleconsultation with a Consultant Medical Geneticist is included to interpret the report, discuss implications for family members, and coordinate further immunological evaluation if needed.
4. Will my insurance cover this genetic test?
Coverage varies by insurance provider and policy. Our team can verify your direct billing eligibility via WhatsApp at +971 54 548 8731. We recommend contacting your insurer to confirm genetic testing benefits prior to scheduling sample collection.
UAE Regulatory & Data Privacy Adherence
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL): All personal genomic data is stored and processed within UAE-secured servers in full compliance with national data protection regulations.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields: Electronic health data exchange and tele-genetic counseling follow mandated security and interoperability standards.
- Federal Decree-Law No. 4 of 2016 on Medical Liability: Patient safety, informed consent, and clinical accountability protocols are strictly observed throughout the testing pathway.
- ISO 9001:2015 Certified: Laboratory processes are certified under certificate INT/EGQ/2509DA/3139, guaranteeing consistent quality management.
Clinical & Logistical Metadata
| Test Name | CORO1A Gene (Immunodeficiency Type 8) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral whole blood (3–5 mL in EDTA tube) |
| Methodology Used | Targeted Next-Generation Sequencing with Sanger confirmation |
| ICD-10-CM Code | D81.2, D81.8, Z15.89 |
| LOINC Code | 82266-3 |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE — DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians