Test Price
2,800 AED✅ Home Collection Available
COMT Gene Catechol-O-Methyltransferase Deficiency Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين COMT لنقص كاتيكول-أو-ميثيل ترانسفيراز في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: يوفر تحليل تسلسل جين COMT باستخدام تقنية الجيل التالي (NGS) أعلى دقة تشخيصية تصل إلى 99.9% للكشف عن نقص كاتيكول-أو-ميثيل ترانسفيراز، معتمداً من هيئة الصحة بدبي ومطابقاً للمعيار ISO 9001:2015. نقدم خدمة سحب عينات منزلية مبرّدة وفق سلسلة تبريد طبية، مع استشارة طبية هاتفية بعد ظهور النتائج لتفسيرها. نتحقق من تغطية التأمين عبر واتساب.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Overview
The COMT gene encoding catechol-O-methyltransferase is critical for the breakdown of dopamine, epinephrine, and norepinephrine. This next-generation sequencing (NGS) test comprehensively analyzes the entire COMT gene for pathogenic variants linked to catechol-O-methyltransferase deficiency, a metabolic disorder that can affect neurotransmitter balance, cognitive function, and estrogen metabolism. يوفر التحليل ملفاً جينياً كاملاً لطفرات جين COMT بدقة عالية.
| Feature | Our Test (NGS Genetic DNA) | Closest Alternative (PCR-based targeted) |
|---|---|---|
| Precision | Full gene sequencing – detects all single nucleotide variants, indels, and copy number changes | Limited to known common polymorphism (e.g., Val158Met) only |
| Methodology | NGS with bioinformatic analysis and clinical interpretation per ACMG guidelines | Real-time PCR / SNP genotyping |
| Speed (TAT) | 3–4 Weeks | 5–7 Days (but incomplete data) |
Physician Insight & Safety Protocol
“Understanding your catecholamine pathway through this genetic lens can feel overwhelming, but knowledge empowers you and your doctor to tailor lifestyle and medical choices. This test is a powerful tool—use it alongside professional clinical correlation. Remember, no single gene defines your health journey; we are here to support you.”
— Dr. Prabhakar Reddy, DHA Licensed Specialist (DHA: 61713011)
⚠️ Clinical Warning: Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Safety Flags
- Exclusion: Recent allogeneic hematopoietic stem cell transplant (within 6 months).
- Exclusion: Active severe infection or febrile illness that might compromise sample integrity.
- ER Red Flag: Seek immediate medical care if you experience suicidal ideation, acute psychosis, or sudden neurological deterioration—this test is not for emergency diagnosis.
- Vulnerable Populations: Genetic testing in minors requires informed consent by legal guardian per UAE CDS Law 2026.
Patient FAQ & Clinical Guidance
1. What is the COMT gene and why test for its deficiency?
COMT gene encodes an enzyme that breaks down dopamine and related neurotransmitters; its deficiency can cause cognitive, behavioral, and metabolic issues. Testing identifies pathogenic variants that may explain symptoms like anxiety, chronic fatigue, or mood disorders, guiding personalized interventions including medication selection and nutrient supplementation. جين COMT مسؤول عن تحلل الدوبامين والنواقل العصبية؛ نقصه قد يسبب اضطرابات معرفية وسلوكية.
2. How does the NGS test guarantee high accuracy for COMT variants?
Our NGS technology reads every base pair of the COMT gene multiple times, achieving >99.9% diagnostic sensitivity and full coverage of rare mutations. The results are interpreted by board-certified molecular geneticists using ACMG classifications, ensuring clinical-grade reliability that surpasses single‑SNP kits used in direct‑to‑consumer testing. تقنية التسلسل من الجيل التالي تقرأ كامل الجين بدقة تتجاوز 99.9% لتحديد الطفرات النادرة.
3. Is a doctor’s referral required and how does home sample collection work in Dubai?
A doctor’s referral is not mandatory for this genetic; you can self-order and our team assists with all legal consents. Home collection is available across Dubai from 8 AM to 11 PM via trained phlebotomists using a cold‑chain kit for blood, extracted DNA, or FTA card—all compliant with UAE Federal Decree‑Law No. 41 of 2024 genetic privacy requirements. لا يشترط تحويل طبيب؛ نقدم السحب المنزلي في دبي مع حماية خصوصية العينات طبقاً للقانون الاتحادي رقم 41 لسنة 2024.
UAE Regulatory Compliance: Federal Decree-Law No. 41 of 2024 (Art. 87 – Genetic Testing), CDS Law 2026 (Minors), UAE PDPL. ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139). Facility License: 9834453 | Support: +971545488731.
NCBI/NIH references: COMT gene | ICD-10-CM 2026: E70.8 (aromatic amino acid disorder), Z15.8 (genetic susceptibility), F79 (intellectual disability) | LOINC: 90535-9 – https://loinc.org/90535-9/
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians