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Test Price

2,800 AED

✅ Home Collection Available

CFAP53 Gene Heterotaxy, Visceral Type 6 Genetic Test | 2800 AED | Dubai, UAE

Executive Summary & Core Metrics

Diagnostic Accuracy: 99.9% sensitivity using ISO 9001:2015 accredited Next‑Generation Sequencing (NGS) for the CFAP53 gene (Cert: INT/EGQ/2509DA/3139).

VIP Mobile Phlebotomy & Cold‑Chain Home Collection: Available daily 8 AM–11 PM. Whole blood collected by DHA‑licensed staff in a validated temperature‑controlled chain.

Post‑Test Clinical Guidance: Telephonic result interpretation with a DHA‑licensed Consultant Medical Geneticist.

Insurance Support: Direct billing verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The CFAP53 Gene Heterotaxy, Visceral Type 6 Genetic Test identifies pathogenic variants in the CFAP53 gene, critical for left‑right axis determination. This single‑gene sequencing test is essential for confirming heterotaxy syndrome in neonates and children presenting with complex congenital heart defects, situs ambiguus, or laterality anomalies, enabling precise medical management and family planning.

Feature Our Test (CFAP53 NGS) Alternative (Chromosomal Microarray)
Technology Next‑Generation Sequencing (NGS) – high coverage, targeted single‑gene analysis Microarray (CNV detection, no single‑base resolution)
Clinical Sensitivity 99.9% for CFAP53 point mutations & small indels ~80% for large structural variants only
Turnaround Time 3–4 weeks 6–8 weeks
Price (AED) 2,800 3,500

Physician Insight & Safety Protocols

“Families facing a suspected heterotaxy diagnosis often experience significant uncertainty. This NGS test delivers definitive molecular confirmation, directly guiding surgical timing and long‑term surveillance. I always emphasise that results must be interpreted alongside detailed echocardiography and imaging; no genetic report replaces a thorough clinical evaluation.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA License 9294403

Advisory & Safety Notice

Do not discontinue any prescribed medication without consulting your physician. Genetic test results do not replace ongoing cardiac care or emergency management. Always correlate with clinical findings and imaging.

Exclusion Criteria & ER Red Flags

  • Testing is contraindicated in asymptomatic individuals without a clinical or family history suggestive of heterotaxy. For minors, consent from a legal guardian is mandatory per Federal Decree‑Law No. 4 of 2016 on Medical Liability.
  • Seek immediate emergency care if the child exhibits cyanosis, respiratory distress, or shock—these symptoms require urgent cardiology/surgical intervention, not a genetic test.
  • This test should not be used for pre‑implantation genetic diagnosis without expert multidisciplinary consultation.

Patient FAQ & Clinical Guidance

1. What does CFAP53 gene testing detect?

CFAP53 gene testing detects mutations causing heterotaxy syndrome, a congenital disorder affecting organ positioning and heart structure. The NGS panel sequences the entire coding region of CFAP53, identifying pathogenic variants that confirm visceral heterotaxy type 6, allowing for accurate prognosis and family screening.

2. How is the test performed?

A simple whole blood draw is collected at your home by a DHA‑licensed phlebotomist using full PPE. The sample is transported in a validated cold chain to our ISO‑accredited laboratory, where Next‑Generation Sequencing is performed. Results are ready in 3–4 weeks.

3. What are the costs and insurance coverage?

The test costs 2,800 AED. We verify insurance coverage directly via WhatsApp at +971 54 548 8731. Many UAE plans cover medically indicated genetic testing; our team handles pre‑approval and eligibility confirmation.

UAE Regulatory & Data Privacy Adherence

This service complies with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is stored within UAE sovereign data centers. ISO 9001:2015 Certificate INT/EGQ/2509DA/3139. DHA Facility License: 1143.

Clinical & Logistical Metadata

Test Name CFAP53 Gene Heterotaxy, Visceral Type 6 Genetic Test
Price (AED) 2,800
Turnaround Time 3–4 weeks
Sample Type / Matrix Whole blood (EDTA)
Methodology Used Next‑Generation Sequencing (NGS) – Single gene sequencing
ICD-10-CM Code Q89.3
LOINC Code 55233-1
DHA Facility License & Address License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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