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Test Price

2,800 AED

✅ Home Collection Available

CD81 Gene Immunodeficiency Common Variable Type 6 Genetic Test in UAE | 2800 AED

Executive Summary & Core Metrics

99.9% Diagnostic Sensitivity: ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).

VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection: Available daily from 8 AM to 11 PM.

Post-Test Clinical Guidance: Telephonic result interpretation by a DHA-licensed genetic counsellor.

Direct Billing Verification: WhatsApp +971 54 548 8731 – Instant pre-approval.

Test Overview & Methodology

The CD81 gene NGS test detects pathogenic variants causing Common Variable Immunodeficiency type 6 (CVID6), an autosomal recessive primary immunodeficiency marked by hypogammaglobulinemia, recurrent sinopulmonary infections, autoimmunity, and increased malignancy risk.

Feature Our Test (NGS) Closest Alternative (Sanger Sequencing)
Precision 99.9% sensitivity for single‑exon & copy‑number variants ~95% sensitivity; may miss large deletions/duplications
Methodology Next Generation Sequencing (NGS) with full gene coverage Sanger sequencing of coding regions; limited to known hotspots
Turnaround Time 3 to 4 weeks 4 to 6 weeks (longer for deletion/duplication reflex)
Sample Flexibility Whole blood, extracted DNA, or one drop on FTA card Typically requires extracted DNA

Physician Insight & Safety Protocols

"A genetic diagnosis of CVID6 must be evaluated alongside immunoglobulin levels and clinical phenotype. NGS provides the comprehensive view needed to guide immunologist-led management. Do not alter therapy without specialist input."

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

⚠ Medication Advisory

Do not discontinue prescribed immunoglobulin therapy, immunosuppressants, or any other medication without consulting your doctor. Abrupt cessation can trigger severe infection or autoimmune flare.

Exclusion Criteria & Emergency Red Flags

  • Exclusion: Blood transfusion within 2 weeks; inadequate pre‑test genetic counselling; inability to provide informed consent (Federal Decree-Law No. 4 of 2016 mandates guardian consent for minors).
  • ER Red Flags: Severe dyspnoea, high fever with rigors, sudden anaphylaxis, or loss of consciousness following blood draw – call 998 immediately.

Patient FAQ & Clinical Guidance

1. What does the CD81 gene test actually diagnose?

This identifies pathogenic variants in the CD81 gene that cause Common Variable Immunodeficiency type 6, a hereditary immune disorder characterised by low antibody levels and recurrent infections.

2. How accurate is the NGS methodology for CD81?

Our NGS assay achieves 99.9% analytical sensitivity and specificity for single‑nucleotide variants and large rearrangements within CD81.

3. Can I use a single drop of blood on an FTA card?

Yes, a single drop of blood on a DNA‑stabilising FTA card is accepted and maintains integrity for NGS analysis.

4. How long does it take to get results?

The turnaround time is 3 to 4 weeks from sample receipt. Urgent cases can be expedited upon request.

UAE Regulatory & Data Privacy Adherence

Your data is protected under:

  • Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – governs patient data privacy and confidentiality.
  • Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – ensures secure handling of electronic health records.
  • ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) – continuous quality improvement in laboratory processes.

Clinical & Logistical Metadata

Test Name CD81 Gene Immunodeficiency Common Variable Type 6 Genetic Test
Price (AED) 2,800 AED
Turnaround Time 3–4 weeks
Sample Type / Matrix Whole blood (EDTA), extracted DNA, or FTA card
Methodology Used Next Generation Sequencing (NGS) – full gene coverage
ICD-10-CM Code D83.8 (Other common variable immunodeficiency)
LOINC Code 81247-9 (DNA sequencing of gene panel)
DHA Facility License & Laboratory Address License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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