Test Price
2,800 AED✅ Home Collection Available
CCDC8 Gene Sequencing for 3‑M Syndrome Type 3 (NGS) in UAE | AED 2,800 | 2026 DHA Guidelines
تحليل جين CCDC8 لمتلازمة 3‑M من النوع الثالث (NGS) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary / ملخص تنفيذي
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited NGS processing.
- Premium Logistics: Paid Hospital‑Grade Home Collection with ISO‑certified cold‑chain transport and VIP mobile phlebotomy.
- Clinical Guidance: Telephonic post‑test interpretation support by certified genetic counsellors.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
نقدم تحليلًا جينيًا دقيقًا لجين CCDC8 باستخدام تقنية التسلسل الجيني القادرة على تحديد الطفرات المسببة لمتلازمة 3‑M من النوع الثالث. يُجرى الفحص وفقًا لأعلى معايير الجودة والخصوصية في دولة الإمارات العربية المتحدة.
Overview
CCDC8 gene sequencing identifies pathogenic variants causing 3‑M syndrome type 3 – a rare autosomal recessive disorder characterised by pre‑ and postnatal growth retardation and distinctive facies. This targeted NGS test offers higher depth and analytical sensitivity than whole‑exome panels, delivering definitive molecular confirmation for dysmorphology evaluation.
يحدد تحليل جين CCDC8 الطفرات المسببة لمتلازمة 3‑M النوع الثالث، وهو اضطراب نادر متنحٍّ يتميز بتأخر النمو وملامح وجهية مميزة.
| Feature | Our Test – CCDC8 NGS | Closest Alternative – Whole Exome Sequencing |
|---|---|---|
| Precision | Single‑gene deep sequencing (500× average depth), detects small indels and CNVs | Genome‑wide screening with variable coverage; may miss deep intronic variants |
| Methodology | Targeted NGS + Sanger validation of all reported variants | Exome capture + NGS; requires secondary confirmation |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
Physician Insight & Safety Protocol
Dr. Prabhakar Reddy, DHA License 61713011: “A targeted CCDC8 test must be correlated with the full clinical picture and a three‑generation pedigree. A negative result does not exclude 3‑M syndrome if other CCDC8 pathogenic variants exist; always discuss findings with a clinical geneticist. This test informs, but does not replace, a thorough dysmorphology evaluation.”
⚠ Medication Warning
Do not discontinue or adjust any prescribed medication based on genetic test results without consulting your treating physician.
Exclusion Criteria & ER Red Flags
- Exclusion: Prenatal diagnosis without prior genetic counselling; asymptomatic minors lacking informed parental consent; patients unable to provide a complete three‑generation family history.
- ER Red Flags: Sudden onset of severe respiratory distress, apnoeic episodes, or acute failure to thrive in a child suspected of 3‑M syndrome – seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What makes this CCDC8 test more accurate than a general genetic panel?
This targeted NGS test achieves 500× average depth on the entire CCDC8 coding region, ensuring 99.9% sensitivity for single‑nucleotide variants, small insertions, deletions, and copy‑number changes – a precision not matched by broad panels.
يحقق هذا الفحص المستهدف عمق قراءة يصل إلى 500× على كامل المنطقة المشفرة لجين CCDC8، مما يضمن حساسية 99.9% للطفرات النقطية والتغيرات الهيكلية الدقيقة.
2. How is the sample collected and what pre‑test steps are required?
A certified phlebotomist draws 2–3 mL of whole blood (or one drop on an FTA card) during a home/office visit; prior genetic counselling and a detailed clinical history are mandatory to ensure accurate variant interpretation.
يتم سحب عينة دم وريدي (2–3 مل) أو قطرة دم واحدة على بطاقة FTA خلال زيارة منزلية؛ ويشترط تقديم تاريخ سريري كامل وجلسة استشارة وراثية مسبقة.
3. Will my insurance cover this test and how do I verify?
Direct billing to all major UAE insurers is available; simply send your policy number and request via WhatsApp to +971 54 548 8731, and our team will confirm coverage within 2 hours before your appointment.
نقدم خدمة الفوترة المباشرة لجميع شركات التأمين الكبرى في الإمارات؛ أرسل رقم وثيقتك عبر واتساب إلى 0545488731 ونتحقق من التغطية خلال ساعتين.
UAE Regulatory Compliance: This service is conducted in strict accordance with Federal Decree‑Law No. 41 of 2024 (Art. 87) on health data confidentiality, the Child Data Safeguarding Law (CDS 2026) on genetic testing of minors, and the UAE Personal Data Protection Law. All processing is performed under ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139). DHA facility license 9834453.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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