Test Price
2,800 AED✅ Home Collection Available
C7 Gene Deficiency Genetic Test in UAE | 2800 AED | NGS Precision Diagnosis
Executive Summary & Core Metrics
Executive Summary
Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO-accredited NGS processing with full bioinformatics verification and Sanger confirmation of clinically significant variants. Premium Logistics: VIP mobile phlebotomy with temperature-controlled cold-chain home collection across all emirates, available daily from 8 AM to 11 PM. Clinical Guidance: Complimentary telephonic post-test consultation for result interpretation by a consultant medical geneticist.
Insurance Direct Billing Verification: WhatsApp +971 54 548 8731
List Price: 2,800 AED (inclusive of genetic counselling and interpretive report)
Test Overview & Methodology
The C7 Gene Deficiency NGS Test is a high-resolution next-generation sequencing analysis of the entire C7 gene, detecting pathogenic variants linked to hereditary complement component 7 deficiency. This primary immunodeficiency markedly elevates the risk for invasive meningococcal disease and systemic lupus erythematosus. The test provides definitive molecular diagnosis, guiding lifelong vaccination, antibiotic prophylaxis, and family screening strategies.
| Feature | Our NGS Test (C7 Full Gene) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Diagnostic Sensitivity | 99.9% for SNVs, indels, CNVs | 95%, limited to targeted exons |
| Methodology | NGS (Illumina) with 100x coverage, bioinformatics pipeline, Sanger confirmation | Sanger sequencing, single amplicon per exon |
| Turnaround Time | 14–21 Business Days | 21–30 Business Days |
| Clinical Reporting | ACMG variant classification + DHA-compliant interpretive report | Basic variant list without full interpretive context |
Physician Insight & Safety Protocols
“This NGS-based C7 gene test delivers definitive molecular evidence for complement deficiency, yet the result must be weighed alongside functional assays like CH50 and AH50, as well as the patient's infection history. A positive finding confirms the genetic substrate for susceptibility to Neisseria meningitidis and autoimmune phenomena, but it never replaces clinical surveillance. Patients should continue prescribed prophylaxis and immunisations while awaiting results.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Safety Advisory
Do not discontinue prescribed prophylactic antibiotics, immunoglobulin therapy, or immunosuppressive agents without consulting your treating specialist.
This genetic test provides diagnostic confirmation only; it does not replace clinical judgment or alter acute treatment decisions. Any modification to therapy must be supervised by an immunologist or geneticist.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients who have undergone allogeneic bone marrow transplantation may yield donor-derived genotype; pre-test genetic counselling and verification of transplant history are mandatory.
- Exclusion: Individuals unable to provide informed consent or for whom complete pedigree information is unavailable may experience delayed or restricted interpretation.
- Red Flags – Seek Immediate Emergency Care: Sudden onset of fever, severe headache, neck stiffness, photophobia, or petechial rash. These signs may indicate meningococcal meningitis and require urgent medical attention regardless of test status or results.
Patient FAQ & Clinical Guidance
1. What does a positive C7 gene test result mean for my health?
Core Answer: A positive result identifies a disease-causing mutation in the C7 gene, confirming hereditary complement deficiency with significantly increased susceptibility to meningococcal infections and systemic lupus erythematosus.
This diagnosis guides the need for lifelong meningococcal vaccination (ACWY and serogroup B), antibiotic prophylaxis, and careful monitoring for autoimmune manifestations. First-degree family members should also undergo genetic counselling and cascade testing.
2. How is the sample collected and is home collection available?
Core Answer: A simple blood draw into an EDTA tube or a capillary blood spot onto an FTA card is collected by a trained phlebotomist. VIP mobile phlebotomy with temperature-controlled cold-chain transport is available across all emirates.
Our service operates daily from 8 AM to 11 PM. The specimen is transported in a validated cold-chain container to preserve DNA integrity. Same-day courier pickup is arranged upon booking confirmation.
3. Is this test covered by insurance in the UAE?
Core Answer: Most UAE insurers cover the C7 NGS test when prescribed by an immunologist or clinical geneticist. Direct billing verification is available via WhatsApp before your appointment.
We work with all major networks including Daman, AXA, NextCare, and others. Simply send your policy details to +971 54 548 8731 and we will confirm coverage within one hour. Self-pay at 2,800 AED is also available.
4. How long does it take to get results, and how will I receive them?
Core Answer: The standard turnaround time is 14 to 21 business days from sample receipt in the laboratory. Results are delivered via secure digital portal and a printed DHA-compliant interpretive report.
A consultant medical geneticist provides a complimentary telephonic consultation to explain the findings, implications for family members, and recommended follow-up steps including vaccination and prophylaxis planning.
UAE Regulatory & Data Privacy Adherence
Federal Data Protection & Health Information Governance
All genetic testing and personal health data processing at DNA Labs UAE strictly complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and informed consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Our laboratory holds DHA facility license number 1143 and maintains ISO 9001:2015 certification. Genomic data is encrypted, access-controlled, and never shared with third parties without explicit written patient consent as required by UAE law.
Clinical & Logistical Metadata
| Test Name | C7 Gene Deficiency Genetic Test (NGS Full Gene Sequencing) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 14–21 Business Days (3–4 Calendar Weeks) |
| Sample Type / Matrix | Whole Blood (3–5 mL in EDTA tube) or FTA Card (Dried Blood Spot) |
| Methodology Used | Next-Generation Sequencing (NGS) – Illumina platform, 100x coverage, bioinformatics variant calling, Sanger confirmation of clinically significant variants |
| ICD-10-CM Code | D84.1 |
| LOINC Code | 95275-6 |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians