Test Price
2,800 AED✅ Home Collection Available
BMPR2 Gene Pulmonary Veno-Occlusive Disease Type 1 Genetic Test in UAE
Executive Summary & Core Metrics
A comprehensive NGS-based genetic analysis for pathogenic variants in the BMPR2 gene associated with pulmonary veno-occlusive disease and heritable pulmonary arterial hypertension, delivered under full DHA regulatory compliance.
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- ✓ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- ✓ Clinical Guidance: Post-test telephonic consultation with a Consultant Medical Genetics for result interpretation.
- ✓ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The BMPR2 gene NGS test is a comprehensive genetic analysis designed to detect pathogenic variants linked to pulmonary veno-occlusive disease (PVOD) and heritable pulmonary arterial hypertension. This test provides crucial information for accurate diagnosis, familial risk assessment, and personalised management in the UAE, delivered with the highest regulatory and clinical standards.
Full gene sequencing via next-generation technology captures single nucleotide variants, small insertions and deletions, and copy number variations across all coding exons and flanking intronic regions, ensuring the most complete mutational spectrum available for clinical decision-making.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Method | NGS (Full Gene Sequencing) | Sanger Sequencing (Targeted Exons) |
| Variant Detection | SNVs, Indels, CNVs (high coverage) | Known point mutations only |
| Diagnostic Sensitivity | 99.9% | ~85% for targeted regions |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Sample Type | Blood, DNA, FTA Card | Blood only |
Physician Insight & Safety Protocols
“BMPR2 genetic testing results must be integrated with a thorough cardiopulmonary evaluation and a three-generation family history to avoid diagnostic misinterpretation. This test is a powerful adjunct, not a standalone diagnosis. Every patient should receive pre- and post-test genetic counselling to fully understand implications for themselves and their at-risk relatives.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Medication & Clinical Advisory
⚠ Continue all prescribed therapies unless explicitly advised otherwise by your treating physician. Abrupt discontinuation of pulmonary vasodilators or anticoagulants may lead to clinical deterioration.
Exclusion Criteria & Emergency Red Flags
- Pregnant or lactating individuals should defer testing until after delivery unless specifically indicated by a specialist.
- Acute decompensated heart failure or hemodynamic instability requires medical stabilisation before blood draw.
- Severe coagulopathy or current anticoagulant therapy at supratherapeutic levels contraindicating venipuncture.
- Seek emergency care immediately if you experience: sudden worsening dyspnea, chest pain, hemoptysis, or syncope.
Patient FAQ & Clinical Guidance
1. What is the BMPR2 gene test for pulmonary veno-occlusive disease?
This NGS test examines the entire BMPR2 gene to identify pathogenic variants that cause pulmonary veno-occlusive disease and heritable pulmonary arterial hypertension, enabling precise clinical management. The analysis can detect both known and novel mutations, offering the most complete genetic picture for affected families.
Cascade testing of first-degree relatives is strongly recommended when a pathogenic variant is identified, as early detection can dramatically alter disease trajectory through timely intervention.
2. How is the sample collected and what is the cost?
A certified phlebotomist collects a small blood sample at your home using a cold-chain kit, and the cost is 2,800 AED inclusive of genetic counselling and reporting. Alternatively, you can provide an FTA card spot after a finger prick, all under the same ISO 9001:2015 protocols.
Mobile phlebotomy is available daily from 8 AM to 11 PM. Courier-based sample drop-off at our Dubai Healthcare City laboratory is also accepted with prior appointment.
3. What do the results mean for my family members?
A positive result indicates a heritable mutation that can be passed to children, prompting cascade testing and early cardiopulmonary surveillance for at-risk relatives. Negative results, when a known familial mutation exists, can provide immense relief and reduce unnecessary monitoring.
Genetic counselling is included in the service to help families understand recurrence risks, reproductive options, and long-term follow-up recommendations tailored to UAE clinical practice guidelines.
4. How long does it take to get results?
The standard turnaround time is 3 to 4 weeks from sample receipt at the laboratory. This accounts for full NGS sequencing, bioinformatics analysis, variant interpretation, and clinical report generation by our Consultant Medical Genetics.
Expedited processing may be arranged on a case-by-case basis for urgent clinical scenarios; please contact our coordination team for details.
UAE Regulatory & Data Privacy Adherence
Fully Compliant with UAE Federal Data Protection & Health Information Governance Frameworks
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – All patient genetic data is processed, stored, and transmitted under strict PDPL consent and data minimisation requirements.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – Electronic health records and telemedicine components of this service adhere to federal ICT security standards for clinical data.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – Patient consent protocols, clinical safety procedures, and professional accountability are governed by this law, ensuring full medico-legal protection.
- ISO 9001:2015 Certified – Quality management system certified under INT/EGQ/2509DA/3139, ensuring consistent diagnostic excellence and continuous process improvement.
Clinical & Logistical Metadata
| Test Name | BMPR2 Gene Pulmonary Veno-Occlusive Disease Type 1 Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood, DNA, FTA Card – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available Daily (8 AM – 11 PM) |
| Methodology Used | Next-Generation Sequencing (NGS) – Full gene sequencing with SNV, Indel, and CNV detection |
| ICD-10-CM Code | I27.0, I27.20, Z15.09 |
| LOINC Code | 48002-0 |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians