Test Price
2,800 AED✅ Home Collection Available
ATRX Gene Sequencing (NGS) for Alpha‑Thalassemia/Mental Retardation Syndrome in UAE | 2800 AED | 2026 DHA Guidelines
تحليل تسلسل جين ATRX لمتلازمة ألفا ثلاسيميا والتخلف العقلي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Diagnostic Precision
99.9% Diagnostic Sensitivity via ISO 15189‑accredited NGS processing and dual‑strand confirmation.
Premium Logistics
Paid Hospital‑Grade Home Collection (8 AM‑11 PM) with ISO‑certified cold‑chain transport. VIP mobile phlebotomy available at no extra charge.
Post‑Test Clinical Guidance
Telephonic result interpretation with a DHA‑licensed genetic counsellor within 48 h of report release.
Insurance & Payment
Direct Billing Verification via WhatsApp +971 54 548 8731. All major UAE insurers accepted.
Overview
The ATRX gene sequencing test detects pathogenic variants in the ATRX gene that cause X‑linked alpha‑thalassemia/mental retardation syndrome (ATR‑X syndrome), characterised by severe intellectual disability, distinctive facial features, urogenital anomalies, and HbH disease. This NGS assay sequences the entire coding region and intron‑exon boundaries, providing a definitive molecular diagnosis and enabling tailored haematological and neurodevelopmental management.
| Feature | Our Test (NGS) | Sanger Sequencing (Alternative) |
|---|---|---|
| Diagnostic Yield | >99.9% of all coding variants, including large indels detected by coverage analysis | ~80 % (misses deep intronic variants and large deletions) |
| Turnaround Time | 3–4 weeks | 6–8 weeks (multi‑amplicon) |
| Method | Targeted NGS on Illumina NovaSeq 6000, aligned to GRCh38, analysed with ISO‑validated bioinformatics pipeline | Capillary electrophoresis, manual variant calling |
| Regulatory Compliance | ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139), Federal Decree‑Law No. 41 of 2024, CDS 2026 | Variable |
Physician Insight & Safety Protocol
“As a DHA‑licensed haematologist, I advise that an ATRX molecular diagnosis must always be correlated with haemoglobin electrophoresis, RBC indices, and neurodevelopmental evaluation. Never interpret a ‘variant of uncertain significance’ as causative without expert genetic counselling.”
— Dr. Prabhakar Reddy, DHA: 61713011
⚠️ Medication & Safety Alert
Do not discontinue prescribed medication without consulting your doctor.
- Exclusion Criteria: Patients with active haemolysis requiring urgent transfusion, or those unable to provide informed consent for genetic testing under UAE law.
- Emergency Red Flags: Severe pallor, acute respiratory distress, seizures, or loss of consciousness occurring while awaiting results – seek immediate medical attention, not laboratory interpretation.
- Sample Rejection: Haemolysed, clotted, or grossly contaminated samples; insufficient DNA quantity (<50 ng/μL).
Expert Clinical Intent
Haematologist
Evaluates HbH disease, management of chronic haemolysis, and transfusion requirements.
Clinical Geneticist
Confirms germline variant inheritance, facilitates cascade testing, and provides recurrence risk counselling.
Paediatric Neurologist
Addresses intellectual disability, seizures, and developmental delay associated with ATR‑X syndrome.
Frequently Asked Questions
What sample types are accepted for the ATRX gene test?
We accept whole blood (3–5 mL in EDTA), extracted DNA, or a single drop of blood blotted on an FTA card, all transported under cold‑chain conditions to preserve nucleic acid integrity.
نقبل عينة دم كامل (3–5 مل في أنبوب EDTA)، أو حمض نووي مستخلص، أو قطرة دم واحدة على بطاقة FTA، جميعها تُنقل بسلسلة تبريد للحفاظ على الحمض النووي.
How should I prepare for the home collection service?
No fasting is required; simply hydrate well and provide your Emirates ID. Our phlebotomist will bring all necessary equipment, including the ISO‑validated cold‑chain vaccine carrier.
لا يلزم الصيام؛ فقط اشرب الماء جيدًا وقدّم هويتك الإماراتية. سيحضر فني السحب جميع المعدات، بما في ذلك حافظة التبريد المعتمدة وفقًا لمعايير ISO.
What is the diagnostic accuracy of this NGS test for ATR‑X syndrome?
With >99.9% analytical sensitivity for single‑nucleotide variants and copy‑number changes, this identifies all known pathogenic ATRX mutations reported in ClinVar and the Human Gene Mutation Database.
بدقة تحليلية تفوق 99.9% للطفرات النقطية وتغيرات عدد النسخ، يكشف هذا الاختبار جميع الطفرات المرضية المعروفة في قاعدة بيانات ClinVar وHGMD.
Legal & Regulatory Compliance
✔ Federal Decree‑Law No. 41 of 2024 on Human Genomics (Art. 87) · ✔ CDS Law 2026 (Minors) · ✔ UAE PDPL (Patient Data Privacy) · ✔ ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) · ✔ DHA Facility License: 9834453
Contact & Verification: +971 54 548 8731
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians