Test Price
2,800 AED✅ Home Collection Available
AMT Gene Glycine Encephalopathy Genetic Test (NGS) in Dubai, UAE | 2,800 AED
Executive Summary & Core Metrics
Comprehensive Molecular Diagnosis for Glycine Encephalopathy
- Diagnostic Sensitivity: 99.9% via ISO-accredited Next-Generation Sequencing of the complete AMT gene coding region.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Post-test telephonic consultation with our Consultant Medical Genetics team for result interpretation and family risk assessment.
- Insurance Support: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced Next-Generation Sequencing (NGS) assay analyzes the complete coding region and flanking exon-intron boundaries of the AMT gene to detect pathogenic variants causative of glycine encephalopathy (nonketotic hyperglycinemia). Results enable definitive molecular diagnosis, reliable carrier detection, and informed family planning for at-risk relatives.
| Feature | Our Test (AMT Gene NGS) | Alternative (Standard Panel) |
|---|---|---|
| Precision | Single-gene full sequencing with 99.9% diagnostic sensitivity | Multigene panel may miss rare deep-intronic or mosaic variants |
| Method | Next-Generation Sequencing with full bioinformatics pipeline | Sanger sequencing of selected exons only |
| Turnaround | 21–28 Business Days | 6–8 Weeks |
| Coverage | Full coding region + flanking intronic regions | Limited exon coverage, no deep-intronic analysis |
Physician Insight & Safety Protocols
"Comprehensive molecular analysis of the AMT gene by NGS provides high-resolution detection of sequence variants essential for the accurate diagnosis of glycine encephalopathy. However, every genetic finding must be interpreted within the full clinical and biochemical context. A negative result does not exclude the diagnosis, and variant classification requires multidisciplinary review. We strongly recommend post-test genetic counseling with a qualified specialist." — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Important Clinical Advisory
Patients should not alter or discontinue any prescribed treatment regimen without explicit direction from their managing physician. This diagnostic test is intended to inform clinical decision-making and is not a substitute for emergency medical care or professional medical advice.
Exclusion Criteria & Emergency Red Flags
Emergency Red Flags Requiring Immediate Medical Attention
- This elective genetic test is not suitable for individuals experiencing acute metabolic decompensation, uncontrolled seizure activity, or deteriorating consciousness.
- Patients presenting with sudden-onset lethargy, hypotonia, or coma must receive urgent emergency evaluation regardless of testing status.
- Sample collection should be deferred for patients on anticoagulant therapy unless explicitly cleared by the supervising clinician.
Patient FAQ & Clinical Guidance
1. What is the AMT Gene Glycine Encephalopathy Genetic Test?
This test uses Next-Generation Sequencing to read the entire coding region of the AMT gene and detect disease-causing variants responsible for glycine encephalopathy (nonketotic hyperglycinemia). It provides a definitive molecular diagnosis and enables carrier testing for family members.
2. How is the sample collected and what is the turnaround time?
A peripheral whole blood sample, extracted DNA, or a single blood spot on an FTA card is collected by our VIP Mobile Phlebotomy team at your home or preferred location. Results are delivered within 21 to 28 business days from sample receipt.
3. Does the test include post-result genetic counseling?
Yes, the test fee includes a telephonic post-result consultation with our Consultant Medical Genetics team. Our specialists will explain your results, discuss inheritance patterns, and provide guidance on family screening and reproductive options.
UAE Regulatory & Data Privacy Adherence
Regulatory & Compliance Assurance
This test is performed under the regulatory oversight of the Dubai Health Authority (DHA Facility License No. 1143). All clinical and genetic data are processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient safety and informed consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. Our laboratory operates under ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | AMT Gene Glycine Encephalopathy Genetic Test (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 21–28 Business Days |
| Sample Type / Matrix | Peripheral Whole Blood, Blood Spot on FTA Card, or Extracted DNA |
| Methodology Used | Next-Generation Sequencing (NGS) – Full Gene Coding Region & Flanking Intronic Regions |
| ICD-10-CM Code | E72.51 |
| LOINC Code | 94222-5 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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