Test Price
2,800 AEDโ Home Collection Available
AIRE Gene Autoimmune Polyendocrinopathy Syndrome Type 1 (APS-1) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Next-Generation Sequencing (NGS) and orthogonal bioinformatic confirmation.
- Premium Logistics: Paid Hospital-Grade Home Collection with ISO Certified Cold-Chain and VIP Mobile Phlebotomy available 8 AM โ 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-licensed clinicians.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The AIRE Gene NGS Test sequences the entire Autoimmune Regulator gene to identify pathogenic variants linked to Autoimmune Polyendocrinopathy Syndrome Type 1 (APS-1), a rare autosomal recessive condition causing multiple endocrine deficiencies, chronic mucocutaneous candidiasis, and ectodermal dystrophy. This high-coverage test delivers a comprehensive molecular diagnosis, empowering clinicians to tailor surveillance and treatment strategies while offering definitive carrier detection for at-risk families.
| Feature | Our AIRE NGS Test | Closest Alternative |
|---|---|---|
| Precision | 99.9% analytical sensitivity & specificity, >100ร coverage | 95โ98%, restricted to known mutation hotspots |
| Method | Next-Generation Sequencing (NGS) with orthogonal Sanger confirmation | Sanger sequencing of selected exons only |
| Turnaround | 3โ4 Weeks | 4โ6 Weeks |
Physician Insight & Safety Protocols
โUnderstanding the genetic underpinning of APS-1 can be life-changing for patients and families. Our AIRE NGS test provides the precision needed for early intervention, but always correlate results with a clinical geneticist. Your journey deserves accurate, compassionate guidance.โ โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Notice
Do not discontinue prescribed medication without consulting your doctor. This test is designed to inform clinical decisions and should not be used to alter ongoing treatments without professional supervision.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients unwilling to undergo mandatory pre-test genetic counselling; individuals with severe coagulopathy contraindicating venipuncture; recent blood transfusion (wait 4 weeks).
- ER Red Flags: Seek immediate emergency care if you develop acute vomiting, profound weakness, dizziness, confusion, or severe hypotension โ these may signal adrenal crisis requiring urgent corticosteroid therapy.
- This test is not intended for asymptomatic minors without parental consent and clearance under Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What is the AIRE Gene NGS Test, and who should consider it?
The AIRE NGS test deciphers the entire AIRE gene sequence to identify pathogenic mutations causing Autoimmune Polyendocrinopathy Syndrome Type 1 with 99.9% diagnostic accuracy. It is recommended for patients presenting with unexplained hypoparathyroidism, adrenal insufficiency, and chronic candidiasis, as well as for family members of affected individuals seeking carrier screening or prenatal planning.
2. How are sample collection and privacy handled?
Our DHA-licensed phlebotomists perform a painless home blood draw using cold-chain transport; every sample is de-identified and processed under strict UAE PDPL data protection, ensuring complete confidentiality. Home collection operates daily from 8 AM to 11 PM, with direct billing support via WhatsApp.
3. When will I receive my results, and how are they explained?
Final NGS report is delivered within 3 to 4 weeks and includes a plain-language summary, variant classification, and a scheduled telephonic session with a clinical genetic counsellor. This ensures you fully understand the clinical significance and any actionable steps, without confusion.
UAE Regulatory & Data Privacy Adherence
This laboratory adheres strictly to the Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, de-identified, and stored within secure UAE-based servers. The facility holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) and operates under DHA Facility License No. 1143. Clinical consultation does not replace in-person medical evaluation.
Clinical & Logistical Metadata
| Test Name | AIRE Gene Autoimmune Polyendocrinopathy Syndrome Type 1 (APS-1) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3-4 Weeks |
| Sample Type / Matrix | Whole Blood (Peripheral) โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available 8 AM โ 11 PM |
| Methodology Used | Next-Generation Sequencing (NGS) with orthogonal Sanger confirmation |
| ICD-10-CM Code | E31.0 |
| LOINC Code | 82900-9 |
| DHA Facility License & Laboratory Address Invariants | DNA Labs UAE | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
ุฏุนู ุซูุงุฆู ุงููุบุฉ ู ุชุงุญ
ุงูุชุญูู ู ู ุงูุชุบุทูุฉ ุงูุชุฃู ูููุฉ
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians