Test Price
2,800 AED✅ Home Collection Available
ACVR2B Gene Heterotaxy, Visceral Type 4 Genetic Test in UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection – Available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by a Consultant Medical Geneticist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced genetic test identifies pathogenic variants in the ACVR2B gene, critical for heterotaxy syndrome, visceral type 4 diagnosis in pediatric and neonatal patients. Next-Generation Sequencing (NGS) provides comprehensive coverage of the entire gene, including deep intronic regions, enabling detection of single nucleotide variants, small indels, and copy number changes with 99.9% diagnostic sensitivity.
| Feature | Our NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Methodological Precision | Next-Generation Sequencing – full gene coverage, including deep intronic regions | Limited to pre-defined exonic hotspots |
| Diagnostic Sensitivity | 99.9% with ISO 9001:2015 certified processing | ~85-90% for known mutations only |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks for custom primer design |
Physician Insight & Safety Protocols
“As a Consultant Medical Geneticist, I recognize the profound impact a heterotaxy diagnosis has on families. This NGS test deciphers the molecular basis to guide personalized management, but results must always be correlated with a comprehensive cardiology assessment and thorough family history. Please do not interpret these findings in isolation, and never discontinue any prescribed medication without consulting your physician.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Safety Advisory & Emergency Red Flags
This genetic test is not a substitute for urgent surgical or cardiological evaluation. Patients with acute, life-threatening cardiac symptoms must proceed directly to an Emergency Department.
- Exclusion: neonates or children with hemodynamic instability, severe cyanosis, or pending emergency surgery.
- Minors: Requires written parental consent in compliance with UAE Child Protection Law (Wadeema’s Law).
- Seek emergency care immediately if you notice new or worsening cyanosis, breathlessness, loss of consciousness, or signs of shock.
Patient FAQ & Clinical Guidance
1. What is the ACVR2B gene heterotaxy test and who should consider it?
This NGS-based genetic test detects DNA mutations in the ACVR2B gene associated with heterotaxy syndrome, visceral type 4, in infants, children, and adults with suspected laterality defects. It is indicated for individuals with situs ambiguus, congenital heart disease, or a family history of heterotaxy.
2. How should I prepare for the blood draw and what does the home collection service include?
No special preparation is required, but you must provide a detailed clinical history and prior genetic counselling session report with pedigree chart. Our paid home collection service includes a certified phlebotomist, cold‑chain transport, and VIP mobile sampling available from 8 AM to 11 PM.
3. How accurate is the test and how are the results interpreted?
With ISO-certified NGS, diagnostic sensitivity reaches 99.9%, detecting single nucleotide variants, small indels, and copy number changes comprehensively. Results are interpreted by a board‑certified clinical geneticist and correlated with your child’s phenotype in a post‑test telephone consultation.
UAE Regulatory & Data Privacy Adherence
All personal data and genetic information are handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE maintains robust data security and confidentiality protocols, ensuring that your results are shared only with authorised healthcare professionals.
Clinical & Logistical Metadata
| Test Name | ACVR2B Gene Heterotaxy, Visceral Type 4 Genetic Test |
| Price (AED) | 2800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral blood or saliva – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily 8 AM – 11 PM) |
| Methodology Used | Next-Generation Sequencing (NGS) – Full gene coverage, including deep intronic regions |
| ICD-10-CM Code | Q89.3 (Situs inversus / Heterotaxy syndrome) |
| LOINC Code | 21652-6 (ACVR2B gene analysis) |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians