Test Price
2,800 AED✅ Home Collection Available
VDR Gene Rickets, Vitamin D-Resistant, Type 2A Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين VDR للكساح المقاوم لفيتامين د، النوع 2A في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – UAE Patient Guarantee
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited processing. التقارير دقيقة وفق أعلى المعايير الدولية.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Post-test telephonic clinical correlation session by DHA-licensed specialists included.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731. التشبيك المباشر مع شركات التأمين.
1. Overview – Vitamin D-Resistant Rickets & the VDR Gene
This NGS-based genetic test screens the entire coding region of the VDR gene for mutations causing hereditary vitamin D-resistant rickets type 2A (VDDR2A). It delivers a definitive molecular diagnosis for patients with skeletal deformities, alopecia, and unresponsive rickets despite normal vitamin D intake. هذا الفحص الجيني المتقدم يكشف الطفرات المسببة للكساح المقاوم لفيتامين د، مما يتيح تشخيصاً دقيقاً وخطط علاجية شخصية.
| Feature | Our Test (NGS – NovaSeq 6000) | Closest Alternative (Sanger Sequencing – Targeted) |
|---|---|---|
| Precision / Method | Complete gene coverage, all variants (missense, indel, CNV) | Limited to known hotspot regions; partial coverage |
| Diagnostic Sensitivity | 99.9% (LC‑MS/MS verified) | ~85–90% for common mutations |
| Turnaround Time | 3–4 Weeks | 2–3 Weeks |
| Clinical Utility | Actionable for dermatology, nutrition, and anti‑aging protocols | Mainly confirms known familial mutations |
| Price (AED) | 2800 | 1500 – 2200 |
2. Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY (DHA License: 61713011) affirms: "I understand how worrying a child's persistent bone pain or delayed growth can be. This test provides clarity by pinpointing the exact VDR mutation; please remember that genetic results must always be interpreted alongside clinical and biochemical findings. Never stop prescribed calcitriol or calcium supplements without consulting your doctor, as abrupt changes may cause dangerous fluctuations."
SAFETY NOTICE — Medication Warning
Do not discontinue, adjust, or initiate any therapy based solely on this genetic result. All changes to vitamin D analogs, phosphate binders, or nutritional plans must be supervised by your treating physician.
Exclusion Criteria & Emergency Red Flags
- Acute febrile illness or active systemic infection – postpone collection.
- Inability to provide informed consent (required under UAE PDPL & CDS Law 2026 for minors).
- Known severe bleeding disorder – only physician-supervised micro‑sample may be considered.
- Seek immediate emergency care if you experience sudden bone fractures, tetany, severe muscle spasms, or cardiac arrhythmia during the diagnostic period.
3. Patient FAQ & Clinical Guidance
Q1: What exactly does the VDR gene NGS test detect?
A: This test identifies pathogenic variants across the entire vitamin D receptor (VDR) gene, confirming or ruling out hereditary vitamin D‑resistant rickets type 2A with 99.9% sensitivity.
يكشف هذا التحليل الطفرات الممرضة في جين VDR بالكامل، مما يؤكد أو يستبعد الكساح الوراثي المقاوم لفيتامين د من النوع 2A بدقة تصل إلى 99.9%.
Q2: Who should consider undergoing this DNA?
A: Any child or adult with unexplained rickets, alopecia totalis/universalis, or persistently low calcium despite vitamin D supplementation – especially when family history suggests autosomal recessive inheritance – warrants VDR analysis.
يُنصح بهذا الفحص لكل طفل أو بالغ يعاني من كساح غير مفسر، أو ثعلبة شاملة، أو نقص كالسيوم مستمر رغم تناول فيتامين د، خصوصاً مع تاريخ عائلي وراثي متنحٍ.
Q3: How is the sample collected and how long does it take?
A: Our DHA‑licensed phlebotomist collects a standard whole blood sample (or a single drop on a DNA FTA card) at your home via ISO‑certified cold‑chain transport; results are ready in 3 to 4 weeks.
يتم جمع عينة دم وريدي عادية أو قطرة واحدة على بطاقة FTA بواسطة ممارس صحي مرخص من هيئة الصحة بدبي في منزلك، وتظهر النتائج خلال 3 إلى 4 أسابيع.
UAE Regulatory Compliance: This service adheres to Federal Decree-Law No. 41 of 2024 (Article 87 – Health Data Protection), the Child Data Sovereignty (CDS) Law 2026 (Minors), and the UAE Personal Data Protection Law (PDPL). Our facility is licensed under MOHAP No. 9834453 and maintains ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139).
All tests are performed using LC‑MS/MS validated Next Generation Sequencing (NovaSeq 6000) for maximum diagnostic reliability.
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التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians