Test Price
2,800 AED✅ Home Collection Available
SDHC Gene Pheochromocytoma Type 3 Genetic Test (NGS) in UAE
Executive Summary & Core Metrics
Executive Summary
This UAE-optimized genetic test delivers 99.9% diagnostic sensitivity via ISO 9001:2015‑accredited NGS sequencing for SDHC-related hereditary pheochromocytoma/paraganglioma type 3. Our premium logistics include VIP mobile phlebotomy with temperature‑controlled cold‑chain home collection (available daily 8 AM–11 PM), post‑test telephonic clinical guidance, and direct insurance billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This next‑generation sequencing (NGS) test analyzes the entire coding sequence of the SDHC gene to identify germline mutations that cause hereditary paraganglioma‑pheochromocytoma syndrome type 3, a condition predisposing to adrenal and extra‑adrenal neuroendocrine tumors. Ideal candidates include oncology patients with early‑onset or bilateral pheochromocytoma, individuals with a strong family history, and researchers enrolling in genetic studies.
| Feature | Our Test (NGS) | Closest Alternative (Sanger) |
|---|---|---|
| Precision | 99.9% analytical sensitivity | ~97% per amplicon |
| Methodology | Illumina NovaSeq sequencing‑by‑synthesis | Capillary electrophoresis (single‑gene) |
| Turnaround | 3–4 weeks | 4–6 weeks |
| Home Collection | VIP cold‑chain 8 AM–11 PM | Limited or absent |
| ISO Accreditation | ISO 9001:2015 (INT/EGQ/2509DA/3139) | Variable |
Physician Insight & Safety Protocols
A word from Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)
“Navigating hereditary cancer risk can feel overwhelming, but this test brings clarity to families affected by pheochromocytoma. The SDHC result is a key piece – it must be interpreted together with your clinical picture, endocrine work‑up, and family history. I encourage every patient to review their report with an experienced genetic counselor or oncologist before making any healthcare decision.”
⛔ Exclusion Criteria & Emergency Red Flags
- Active febrile illness or systemic infection – blood draw should be deferred until recovery.
- Inability to provide informed consent; for minors, legal guardian consent is mandatory per Federal Decree‑Law No. 4 of 2016 on Medical Liability.
- Recent blood transfusion (<2 weeks) may interfere with DNA extraction quality.
- Seek emergency care if you experience sudden severe headache, palpitations with hypertension, excessive sweating, or chest pain, as these may indicate an acute catecholamine crisis unrelated to the test itself.
Medication Warning: Do not discontinue any prescribed anti‑hypertensive, alpha‑blocker, or other medication without prior consultation with your treating physician.
Patient FAQ & Clinical Guidance
1. What is the SDHC gene, and how does its mutation lead to pheochromocytoma type 3?
The SDHC gene encodes a critical protein of the mitochondrial succinate dehydrogenase complex; a pathogenic mutation disrupts cellular energy metabolism, triggering hereditary paraganglioma‑pheochromocytoma syndrome type 3 with high risk for adrenal and extra‑adrenal tumors.
2. How is this NGS performed, and what makes it 99.9% accurate?
We sequence the entire SDHC coding region using Illumina NovaSeq technology with an average depth of coverage >500×, then align reads with the human reference genome to call even low‑frequency variants at 99.9% analytical sensitivity.
3. How are my genetic data protected under UAE law?
Under Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, your genetic information is strictly confidential, stored encrypted on UAE‑based servers, and used exclusively for clinical diagnosis; no third‑party sharing occurs without your explicit consent.
UAE Regulatory & Data Privacy Adherence
This test is performed at DNA Labs UAE, a DHA‑licensed facility (License No. 1143). All genetic data handling complies with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019. Patient consent is obtained in accordance with Federal Decree‑Law No. 4 of 2016 on Medical Liability. Results are transmitted through encrypted channels and are accessible only to the patient and the requesting physician.
Clinical & Logistical Metadata
| Test Name | SDHC Gene Pheochromocytoma Type 3 Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks (21–28 business days) |
| Sample Type / Matrix | Peripheral whole blood (3–5 mL in EDTA tube) or saliva collection kit |
| Methodology Used | Next‑generation sequencing (NGS): Illumina NovaSeq, >500× average coverage |
| ICD-10-CM Code | D44.1 |
| LOINC Code | 78059-5 |
| DHA Facility License & Laboratory Address | Licence No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians