Test Price
2,800 AED✅ Home Collection Available
SUMO1 Gene Orofacial Cleft Type 10 Genetic Test in UAE | Comprehensive NGS Analysis
Executive Summary & Core Metrics
Executive Summary: DNA Labs UAE delivers a definitive genetic analysis of the SUMO1 gene, the gold standard for diagnosing orofacial cleft type 10 through massively parallel next‑generation sequencing.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity and Specificity via ISO‑accredited NGS with proprietary variant interpretation pipelines.
- Premium Logistics: VIP Mobile Phlebotomy and Temperature‑Controlled Cold‑Chain Home Collection available daily from 8 AM to 11 PM across all emirates.
- Clinical Guidance: Complimentary telephonic post‑test clinical interpretation session with our DHA‑licensed Consultant Medical Genetics, Ms. Lina Osama Zaki Quteineh.
- Insurance Support: Direct billing verification available via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This advanced genetic test uses next‑generation sequencing (NGS) to interrogate the entire coding region and exon–intron boundaries of the SUMO1 gene, identifying pathogenic variants that cause orofacial cleft type 10—a syndromic form of cleft lip and palate. The high‑depth coverage (300× mean) ensures detection of single‑nucleotide variants, small insertions and deletions, and copy‑number alterations across the full gene locus.
| Feature | Our Test (NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Methodology | Massively parallel next‑generation sequencing with 300× mean coverage | Targeted capillary sequencing of individual exons |
| Variant Detection Scope | SNVs, indels, CNVs, and deep intronic variants across the entire SUMO1 gene | Limited to requested exon; misses CNVs and deep intronic changes |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks (sequential exon requests) |
| Price (AED) | 2,800 | Variable; often higher when multiple exons are required |
Physician Insight & Safety Protocols
“As a DHA‑licensed Consultant Medical Genetics (DHA ID 9294403), I emphasize that the SUMO1 NGS test provides a precise molecular diagnosis that must be integrated with full clinical evaluation and family history. A multidisciplinary team—including a paediatrician, clinical geneticist, and craniofacial surgeon—remains the cornerstone of comprehensive care. This test is a powerful diagnostic complement, not a replacement for expert clinical assessment. Our team is available to discuss any concerns following result disclosure.”
— Ms. Lina Osama Zaki Quteineh, Consultant Medical Genetics
Advisory: Safety Protocols and Informed Consent
All genetic testing performed at DNA Labs UAE adheres to the clinical safety and patient consent requirements outlined in Federal Decree‑Law No. 4 of 2016 on Medical Liability. Pre‑test genetic counselling is provided to ensure the patient or guardian fully understands the scope, limitations, and potential implications of the results. A written informed consent form must be signed prior to sample collection. The test is conducted exclusively under a valid physician referral and is not available for direct consumer purchase without clinical oversight.
Exclusion Criteria and Emergency Red Flags
- Not a stand‑alone screening tool: This test is not indicated for asymptomatic individuals without a personal or documented family history of orofacial clefting, unless specifically prescribed for reproductive risk assessment by a qualified physician.
- Acute clinical symptoms require immediate care: If an infant presents with sudden respiratory distress, cyanosis, or severe feeding intolerance, seek emergency medical attention without delay. Genetic testing is not an emergency diagnostic procedure.
- Negative result does not rule out the condition: A negative SUMO1 sequencing result does not completely exclude orofacial cleft type 10, as other genetic or environmental factors may be causative. Clinical correlation remains essential.
Patient FAQ & Clinical Guidance
1. What is the SUMO1 Gene Orofacial Cleft Type 10 genetic test?
This comprehensive NGS test detects pathogenic variants in the SUMO1 gene that are causally linked to orofacial cleft type 10—a syndromic form of cleft lip and palate. Results provide a molecular diagnosis that informs surgical planning, recurrence risk counselling, and monitoring for associated health conditions.
2. How is the sample collected and what specimen types are accepted?
The test accepts a standard peripheral venous blood draw, a dried blood spot on an FTA card, or previously extracted genomic DNA of adequate quality. No fasting or discontinuation of medications is required. Our VIP Mobile Phlebotomy and Temperature‑Controlled Cold‑Chain Home Collection service operates daily from 8 AM to 11 PM across all emirates.
3. Who should consider this genetic test?
The test is appropriate for infants or children diagnosed with orofacial cleft, individuals with a strong family history of clefting, and couples planning a pregnancy who seek carrier or recurrence risk assessment. Testing must always be undertaken under the guidance of a qualified healthcare provider.
4. How long does it take to receive results and how are they delivered?
The standard turnaround time is 3–4 weeks from sample receipt. Results are delivered via a secure digital portal and reviewed in a complimentary telephonic session with our Consultant Medical Genetics, Ms. Lina Osama Zaki Quteineh, who will explain the clinical implications and recommend next steps.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Security: All patient genetic data is processed and stored in compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Results are encrypted end‑to‑end, access is restricted to authorized clinical personnel only, and identifiable genetic information is never shared with third parties without explicit written consent. DNA Labs UAE holds ISO 9001:2015 certification (Cert. No. INT/EGQ/2509DA/3139) and is licensed by the Dubai Health Authority under Facility License No. 1143.
Clinical & Logistical Metadata
| Test Name | SUMO1 Gene Orofacial Cleft Type 10 Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood, FTA Card, or Extracted DNA |
| Methodology Used | Next Generation Sequencing (NGS) – 300× Mean Coverage |
| ICD-10-CM Code | Q37.9 |
| LOINC Code | 81247-9 |
| DHA Facility License & Address | License No. 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians