Test Price
2,800 AED✅ Home Collection Available
SATB2 Gene Glass Syndrome Genetic Test in UAE 2800 AED DHA-Certified Genetic Diagnostics
Executive Summary and Core Metrics
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO-Accredited NGS Processing covering all coding exons splice-site junctions and clinically relevant intronic regions of the SATB2 gene.
- ✓ Premium Logistics: VIP Mobile Phlebotomy and Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM across all seven Emirates.
- ✓ Clinical Guidance: Complimentary telephonic post-test clinical guidance for result interpretation by a DHA-licensed clinical genetic counselor.
- ✓ Insurance: Direct billing verification via WhatsApp at +971 54 548 8731 with pre-authorization confirmed within 60 minutes during business hours.
ISO 9001:2015 Certified
2800 AED
All-Inclusive
Turnaround Time: 3 to 4 Weeks
Test Overview and Methodology
The SATB2 Gene Glass Syndrome Genetic Test is a definitive molecular diagnostic assay that utilizes Next Generation Sequencing to analyze the entire coding region of the SATB2 gene located at chromosomal locus 2q33.1. Mutations in SATB2 are causative for Glass syndrome a rare autosomal dominant neurodevelopmental disorder characterized by intellectual disability severe speech impairment craniofacial dysmorphism dental anomalies and cleft palate. This test provides a comprehensive molecular evaluation for patients presenting with clinical features consistent with SATB2-associated syndrome.
| Feature | Our NGS Test ISO-Certified | Closest Alternative Sanger or CMA |
|---|---|---|
| Methodology | Next Generation Sequencing with full gene coverage including exons splice sites and regulatory intronic regions | Targeted Sanger sequencing limited to known hotspots or Chromosomal Microarray detecting only large deletions above 50 kb |
| Diagnostic Precision | 99.9% Sensitivity detecting SNVs indels and copy number variants in a unified workflow | Approximately 70 to 85 percent Sensitivity missing deep intronic regulatory and mosaic variants requiring sequential reflex testing |
| Turnaround Time | 3 to 4 Weeks with ISO 9001:2015 accredited processing and dual-clinician variant interpretation | 6 to 12 Weeks with fragmented workflow across multiple laboratories and higher rate of inconclusive reports |
| Clinical Utility | Comprehensive informing prognosis recurrence risk counseling and eligibility for emerging targeted therapies | Partial requiring additional testing with limited utility for familial variant segregation analysis |
Physician Insight and Safety Protocols
As a consultant medical genetics specialist I emphasize that the SATB2 NGS test result must always be interpreted in the context of a comprehensive clinical evaluation. A positive result confirms the molecular diagnosis and empowers families with clarity for recurrence risk counseling and early intervention planning. A negative result however does not exclude the diagnosis if clinical suspicion remains high as mosaic variants promoter-region mutations or epigenetic modifiers may warrant broader genomic investigation. I urge all families to seek structured genetic counseling before and after testing to fully understand the implications for their child health trajectory.
— Dr. Lina Osama Zaki Quteineh Consultant Medical Genetics DHA Registration ID: 9294403
Critical Medication Advisory
Do not discontinue any prescribed medication or alter your child therapeutic regimen without consulting your treating physician. This genetic test is a diagnostic tool and does not replace ongoing clinical management. Results may take up to 4 weeks so continue all prescribed treatments including anti-epileptics speech therapy and nutritional plans during the testing period.
Patient Safety Exclusion Criteria and Emergency Red Flags
Exclusion Criteria for Home Collection
- Active febrile illness with temperature at or above 38.5 degrees Celsius
- Known bleeding diathesis or platelet count below 50000 per microliter without hematologist clearance
- Recent blood transfusion less than 14 days prior which may cause donor DNA interference
- Current chemotherapy cycle requiring coordination with oncologist for optimal collection window
- Neonates weighing less than 2.5 kilograms requiring NICU-based phlebotomy not home collection
Emergency Red Flags Seek Immediate Medical Attention
- New-onset seizures or status epilepticus in the patient
- Respiratory distress or cyanosis unresponsive to home oxygen
- Severe feeding difficulties with weight loss exceeding 10 percent of body weight in one week
- Signs of increased intracranial pressure including persistent vomiting lethargy or bulging fontanelle in infants
- Acute behavioral regression with loss of previously acquired motor or language skills
Emergency Contact: Call 998 UAE Ambulance or visit your nearest emergency department immediately for any of the above red-flag symptoms. This genetic testing service does not provide emergency medical care.
Patient FAQ and Clinical Guidance
1. What is the SATB2 Gene Glass Syndrome NGS Test and why is it clinically important for my child?
The SATB2 NGS test is a comprehensive genetic analysis that sequences the entire SATB2 gene to identify pathogenic mutations causing Glass syndrome a rare autosomal dominant disorder characterized by intellectual disability absent or severely impaired speech distinctive craniofacial features and dental anomalies. This test provides a definitive molecular diagnosis enabling early intervention planning accurate recurrence risk assessment for future pregnancies and access to syndrome-specific multidisciplinary care pathways. Clinical diagnosis alone is often insufficient due to phenotypic overlap with other neurodevelopmental disorders making molecular confirmation through NGS the gold standard for precision diagnosis.
2. How is the sample collected for this test and what is the exact turnaround time in the UAE?
Sample collection is performed via a minimally invasive venous blood draw of 3 to 5 milliliters in an EDTA tube or alternatively using a dried blood spot on an FTA card from a single finger-prick drop with extracted DNA also accepted if previously banked. Our DHA-licensed mobile phlebotomy team provides hospital-grade home collection across all seven Emirates between 8 AM and 11 PM utilizing ISO-certified cold-chain logistics to preserve DNA integrity during transport to our central laboratory. The standard turnaround time is 3 to 4 weeks from sample accessioning to final clinical report issuance with expedited processing of 2 weeks available upon request for urgent clinical scenarios subject to additional fees and prior approval.
3. Does health insurance in the UAE cover the SATB2 Gene Glass Syndrome Genetic Test?
Most UAE-based comprehensive health insurance plans provide coverage for medically indicated genetic testing when accompanied by a referral letter from a DHA-licensed pediatrician clinical geneticist or neurologist documenting clinical suspicion of Glass syndrome based on established diagnostic criteria. Our dedicated insurance verification team processes direct billing approvals via WhatsApp at +971 54 548 8731 simply send a photo of your insurance card and the physician referral and we will confirm coverage within 60 minutes during business hours. For plans with genetic testing exclusions or high deductibles we offer transparent self-pay packages at 2800 AED with no hidden charges.
UAE Regulatory and Data Privacy Adherence
This diagnostic service complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) governing genetic data privacy and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields for secure health data handling. Clinical testing safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. All patient genomic data is stored on encrypted UAE-sovereign servers with strictly controlled access. Results are for clinical diagnostic purposes and must be interpreted by a qualified healthcare professional.
DHA Facility License: 1143 | Premises 105 Floor 1 Building 33 Dubai Healthcare City Dubai UAE | DNA Labs UAE
Clinical and Logistical Metadata
| Test Name | SATB2 Gene Glass Syndrome Genetic Test by NGS |
| Price (AED) | 2800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood 3-5 mL K2-EDTA Extracted DNA or Dried Blood Spot FTA Card |
| Methodology Used | Next Generation Sequencing NGS with Full Gene Coverage |
| ICD-10-CM Code | Q87.89 |
| LOINC Code | 28446-7 |
| DHA Facility License and Laboratory Address | License 1143 Premises 105 Floor 1 Building 33 Dubai Healthcare City Dubai UAE DNA Labs UAE |
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HIPAA
All reports reviewed by DHA-Certified physicians