Test Price
2,800 AED✅ Home Collection Available
MARS2 Gene Combined Oxidative Phosphorylation Deficiency Type 25 (COXPD25) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين MARS2 لنقص الفسفرة التأكسدية المشترك النوع 25 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: اختبار جين MARS2 بتقنية التسلسل الجيني المتقدم بدقة تشخيصية 99.9%، مع خدمة سحب الدم المنزلي الممتازة والمعتمدة من الهيئة، وإرشادات سريرية بعد النتيجة، والتحقق من التغطية التأمينية عبر واتساب.
- ● Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Laboratory.
- ● Premium Logistics: Hospital-Grade Home Collection with ISO Certified Cold-Chain and VIP Mobile Phlebotomy (8 AM – 11 PM).
- ● Clinical Guidance: Post‑test telephonic interpretation with DHA‑licensed genetic counsellors.
- ● Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Overview
The MARS2 Gene NGS Test identifies pathogenic variants causing Combined Oxidative Phosphorylation Deficiency Type 25 (COXPD25), a rare autosomal recessive mitochondrial disorder. This test employs Next-Generation Sequencing to provide definitive molecular confirmation, essential for guiding metabolic and neurological management. يُجرى هذا الاختبار الجيني المتطور للكشف عن الطفرات المسببة لاضطراب نقص الفسفرة التأكسدية المشترك من النوع 25، وهو مرض ميتوكوندري نادر، مما يدعم التشخيص الدقيق والاستشارة الوراثية.
| Feature | Our Test (MARS2 NGS) | Closest Alternative |
|---|---|---|
| Precision | Whole‑gene coverage, variant‑level resolution | Sanger sequencing of selected exons only |
| Method | NGS (Illumina platform, ISO 9001:2015) | Conventional PCR‑based fragment analysis |
| Turnaround | 3–4 Weeks (average 18 days) | 4–6 Weeks |
Physician Insight & Safety Protocol
“As a clinical pathologist, I emphasise that a positive MARS2 mutation indicates a genetic predisposition to oxidative phosphorylation deficiency but must be integrated with biochemical, neuroimaging, and family history. This test is a tool, not a stand‑alone diagnosis — genetic counselling is mandatory. Do not alter any current treatment without full clinical correlation.”
— Dr. PRABHAKAR REDDY, DHA License 61713011
Medication Warning: Do not discontinue prescribed medication or supplements without consulting your managing physician. Mitochondrial supportive therapies require careful, supervised tapering.
⚠ Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Active fever >38.5°C, uncontrolled seizure within 24 hours, or acute metabolic crisis.
- Exclusion: Therapeutic anticoagulation (e.g., warfarin) without physician clearance for venipuncture.
- Exclusion: Known severe needle phobia with vasovagal syncope history — request medical escort.
- ER Red Flags post‑draw: severe pallor, shortness of breath, loss of consciousness, or bleeding that doesn’t stop with pressure.
Patient FAQ & Clinical Guidance
1. What does the MARS2 gene test detect and why is it ordered?
Direct Answer This NGS test detects pathogenic mutations in the MARS2 gene to confirm Combined Oxidative Phosphorylation Deficiency Type 25, a rare metabolic disorder. It is ordered when clinical symptoms like lactic acidosis, hypotonia, and multisystem involvement suggest a mitochondrial disease, or when a family history warrants carrier screening. The test sequences the entire coding region, enabling precise genetic counselling and family risk assessment. يكتشف هذا الاختبار الطفرات المسببة للأمراض في جين MARS2 لتأكيد نقص الفسفرة التأكسدية المشترك من النوع 25، وهو اضطراب استقلابي نادر.
2. How is the sample collected and what is the turnaround time?
Direct Answer A blood sample (whole blood, FTA card, or extracted DNA) is collected via VIP home phlebotomy between 8 AM and 11 PM; results are delivered in 3 to 4 weeks. Our DHA‑licensed phlebotomists follow ISO cold‑chain protocols to maintain DNA integrity. The pre‑test genetic counselling session (pedigree chart required) ensures the sample submission meets laboratory acceptance criteria. يتم جمع عينة الدم (دم كامل أو بطاقة FTA أو حمض نووي مستخلص) عبر خدمة السحب المنزلي المعتمدة، وتظهر النتائج خلال 3 إلى 4 أسابيع.
3. Is this test covered by UAE insurance and what do I need for reimbursement?
Direct Answer Most UAE insurers cover genetic testing when a physician referral, detailed clinical notes, and the pre‑ counselling report are provided; we verify your coverage via WhatsApp. Send your insurance card and referral to +971 54 548 8731 before the draw. Our billing team will handle pre‑authorisation requests and direct billing to all major networks, minimising your out‑of‑pocket expense. تغطي معظم شركات التأمين في الإمارات هذا الاختبار عند تقديم إحالة الطبيب وتقرير الاستشارة الوراثية؛ نتحقق من تغطيتك عبر واتساب.
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التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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