Test Price
2,800 AEDโ Home Collection Available
๐ Results in 3โ4 Weeks
FLNA Gene NGS Test for Melnick-Needles Syndrome | DNA Labs UAE | 2,800 AED
Executive Summary & Core Metrics
๐ฌ Diagnostic Accuracy Guarantee:
99.9% diagnostic sensitivity via ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139).
๐ Premium Home Collection Logistics:
VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
๐ Post-Test Clinical Guidance:
Telephonic result interpretation and genetic counseling delivered by Consultant Medical Genetics, Lina Osama Zaki Quteineh (DHA ID: 9294403).
๐ณ Insurance & Billing:
Direct billing verification via WhatsApp +971 54 548 8731.
Executive Summary Clearance:
This NGS-based analysis of the FLNA gene provides a definitive molecular diagnosis for Melnick-Needles syndrome, enabling targeted clinical management and informed family planning. The test strictly adheres to DHA regulatory frameworks for genetic testing and data privacy.
Test Overview & Methodology
The FLNA gene Next-Generation Sequencing (NGS) test identifies pathogenic variants causing Melnick-Needles syndrome, a rare X-linked dominant skeletal dysplasia with neurological involvement. This comprehensive analysis offers a definitive molecular diagnosis, enabling tailored clinical management and genetic counseling.
| Feature | Our Test (FLNA NGS) | Alternative: Single-Gene Sanger Sequencing |
|---|---|---|
| Precision | >99.9% sensitivity, full coding region coverage | ~95%, limited to known hotspot mutations |
| Methodology | NGS with comprehensive bioinformatics variant filtering | Sanger sequencing (partial gene coverage) |
| Turnaround Time | 3โ4 Weeks | 6โ8 Weeks |
| Regulatory Alignment | DHA/MOHAP Standards, ISO 9001:2015 | Variable |
Physician Insight & Safety Protocols
โAs a Consultant Medical Genetics at DNA Labs UAE, I confirm that comprehensive NGS-based sequencing of the FLNA gene provides the highest degree of molecular accuracy for diagnosing Melnick-Needles syndrome. However, genetic results must always be interpreted within the full clinical context, including family history and physical examination findings. Our service includes mandatory post-test genetic counseling to support patients and their families in understanding the implications of their results.โ โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Medical Advisory
Do not discontinue or alter any prescribed medications based on genetic test results alone. Always consult your referring physician or a qualified specialist before making clinical decisions. Genetic testing is a diagnostic aid, not a substitute for professional medical judgment.
Patient Exclusion Criteria & Emergency Red Flags
Exclusion Criteria:
- Inability to provide informed consent, or lack of legal guardian consent for minors, as outlined under Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Recent blood transfusion (within 2 weeks) if sampling for DNA extraction from whole blood.
๐จ Emergency Red Flags (Seek Immediate Care):
- Acute neurological deficits (sudden weakness, vision loss, speech difficulties).
- Seizures involving loss of consciousness or status epilepticus.
- Signs of increased intracranial pressure (severe headache with vomiting, papilledema).
Patient FAQ & Clinical Guidance
1. What is the clinical accuracy of the FLNA NGS test?
The FLNA NGS test delivers a diagnostic sensitivity exceeding 99.9% for detecting pathogenic variants associated with Melnick-Needles syndrome, establishing it as the gold standard for definitive molecular diagnosis.
2. What sample types are accepted, and how is collection managed?
We accept peripheral whole blood, extracted DNA, or dried blood spots on FTA cards. A certified phlebotomist can collect the sample at your home via our VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, available daily from 8 AM to 11 PM, ensuring strict sample integrity.
3. Who will interpret my results, and what support is provided?
Your report is reviewed and interpreted by a DHA-licensed Consultant Medical Genetics, Lina Osama Zaki Quteineh (DHA ID: 9294403). A comprehensive telephonic consultation is provided to explain the results, clinical implications, and recommended management steps.
UAE Regulatory & Data Privacy Adherence
๐ Data Privacy & Security: Strictly compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
๐ก๏ธ Clinical Safety & Consent: All procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring fully informed patient consent and clinical safety protocols.
๐ฅ Laboratory Accreditation: DNA Labs UAE is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) and operates under DHA Facility License Number 1143.
๐ Physical Address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | FLNA Gene (Melnick-Needles Syndrome) NGS Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood, Extracted DNA, or Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) with Bioinformatic Variant Filtering |
| ICD-10-CM Code | Q87.8 |
| LOINC Code | 94222-0 |
| DHA Facility License & Address | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | License No: 1143 |
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Available in Arabic, English, Hindi & Urdu
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Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians