Test Price
2,800 AED✅ Home Collection Available
COA8 Gene Genetic Test for Mitochondrial Complex IV Deficiency in UAE | 2800 AED
Executive Summary & Core Metrics
- ✓ Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited NGS processing (Cert: INT/EGQ/2509DA/3139).
- ✓ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- ✓ Clinical Guidance: Telephonic post-test clinical correlation session to interpret results with a DHA-licensed genetic counsellor.
- ✓ Insurance: Direct billing verification and pre‑approval via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The COA8 gene NGS test comprehensively analyses the entire coding region of the COA8 gene to identify pathogenic variants linked to mitochondrial complex IV deficiency—a disorder that can lead to severe neurological impairment. In the UAE, access to this advanced genomic assay empowers early, precise diagnosis and personalised care planning under DHA-approved protocols.
| Feature | Our Test (NGS Full Gene) | Closest Alternative (Targeted Panel) |
|---|---|---|
| Method | Next‑Generation Sequencing (100% coding region coverage) | PCR‑based targeted mutation panel (limited sites) |
| Diagnostic Sensitivity | ≥99.9% for single‑exon & splice‑site variants | ~85‑90% (misses rare/novel variants) |
| Turnaround Time | 3‑4 weeks from sample receipt | 4‑6 weeks |
| Price (AED) | 2,800 | 3,200‑3,800 |
Physician Insight & Safety Protocols
“This NGS test provides high‑resolution genetic data that can pinpoint the molecular cause of mitochondrial complex IV deficiency. However, a definitive clinical diagnosis must always integrate biochemical findings and detailed neurological assessment. We encourage all patients to discuss results with their treating physician before making any treatment decisions.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Essential Safety Information
- Exclusion Criteria: Active, uncontrolled seizure disorder; current use of anticoagulants without physician clearance; pregnancy (requires specialised counselling).
- ER Red Flags: If you experience sudden vision loss, severe muscle weakness, breathing difficulties, or altered consciousness, proceed immediately to the nearest emergency department.
- Medication Warning: Do not discontinue any prescribed medication (especially antiepileptics or metabolic supplements) without consulting your doctor prior to or after testing.
Patient FAQ & Clinical Guidance
1. What does the COA8 gene test detect and how accurate is it?
The test detects pathogenic DNA variants in the COA8 gene responsible for mitochondrial complex IV deficiency with over 99.9% sensitivity.
Our NGS‑based analysis reads every coding nucleotide of the COA8 gene, identifying missense, nonsense, splice‑site, and small insertion/deletion mutations. The ISO‑certified laboratory follows DHA‑endorsed protocols, and results are validated by a board‑certified molecular geneticist. A negative result significantly reduces—but does not eliminate—the possibility of other mitochondrial disorders.
2. How is the sample collected and what is the turnaround time?
A simple blood draw or FTA card spot can be done at your home by our VIP phlebotomy team, and results are ready in 3‑4 weeks.
After a brief genetic counselling session (telephone or in‑clinic) to draw a family pedigree, a certified phlebotomist arrives at your preferred location between 8 AM and 11 PM. The sample is transported in a temperature‑controlled cold chain to our Dubai central lab. Once sequencing is complete, a detailed clinical report is issued, and a post‑test tele‑consultation is provided to explain the findings.
3. Do I need a referral and is the test covered by insurance?
A physician’s referral is recommended but not mandatory; many UAE insurers cover this after pre‑approval via our direct billing service.
If you have a neurology or genetics consultation, the referral streamlines insurance claims. Our dedicated insurance team will verify your coverage via WhatsApp at +971 54 548 8731 before sample collection. For self‑pay patients, the cost is 2800 AED, and flexible payment plans are available.
UAE Regulatory & Data Privacy Adherence
Compliance Framework
This diagnostic service is conducted in strict accordance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is processed within a secure, ISO 9001:2015 accredited environment, ensuring medical confidentiality and patient rights. Clinical safety and patient consent follow Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | COA8 Gene Genetic Test for Mitochondrial Complex IV Deficiency |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks from sample receipt |
| Sample Type / Matrix | Peripheral Whole Blood or FTA Card Spot |
| Methodology Used | Next-Generation Sequencing (NGS), full coding region coverage |
| ICD-10-CM Code | E88.89 |
| LOINC Code | 96519-4 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians