Test Price
2,800 AED✅ Home Collection Available
ALS2 Gene Spastic Paralysis, Infantile Onset Ascending NGS Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين ALS2 (الشلل التشنجي، البدء الطفلي الصاعد) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
🔬 Executive Medical Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Laboratory Processing.
- Premium Logistics: Hospital-Grade Home Collection with ISO Certified Cold-Chain Transport and VIP Mobile Phlebotomy (8 AM – 11 PM across UAE).
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Interpretation by DHA-Licensed Pathologist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
مدعوم بضمان دقة تشخيصية بنسبة 99.9% وعينة منزلية عبر سلسلة تبريد معتمدة وتوجيه طبي هاتفي.
Comprehensive Overview
The ALS2 gene NGS test screens for pathogenic variants responsible for infantile-onset ascending spastic paralysis, a severe hereditary neurological disorder. Our UAE-based laboratory delivers definitive molecular confirmation with a 3–4 week turnaround, empowering families and physicians with accurate, actionable results. يُقدم هذا الفحص الجيني تأكيدًا دقيقًا للشلل التشنجي الطفلي الصاعد المرتبط بجين ALS2.
| Parameter | Our Test (NGS) | Alternative (Sanger Sequencing) |
|---|---|---|
| Target Region Coverage | Full gene (all exons, intron boundaries) | Limited to known hotspots only |
| Variant Detection Sensitivity | 99.9% | ~85% for single nucleotide variants |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Sample Types Accepted | Blood, Dried Blood Spot, Extracted DNA | Blood only |
| Price (AED) | 2800 | 1800–2200 (but may require multiple tests) |
ملاحظات الطبيب المعتمد وإجراءات السلامة
“As a DHA-licensed Clinical Pathologist, I want to reassure families that while this test provides a molecular diagnosis, it must be correlated with clinical findings. An identified ALS2 mutation confirms the condition, but a negative result does not exclude other hereditary spastic paraplegias—further testing may be warranted. Above all, never adjust your child’s treatment plan without medical supervision.”
— Dr. PRABHAKAR REDDY, DHA License No. 61713011
⚠️ Medication Warning:
Do not discontinue or modify any prescribed medication, including spasticity management drugs (e.g., baclofen, tizanidine), without explicit consultation with your treating neurologist or paediatrician.
🚨 Exclusion Criteria & Emergency Red Flags
- Exclusion: Samples from individuals < 1 week of age (neonatal screening not applicable).
- Exclusion: Inability to provide informed consent or absence of a legal guardian for minors.
- ER Red Flag: Acute respiratory distress, aspiration pneumonia, or new-onset seizures—seek immediate emergency care.
- ER Red Flag: Rapid worsening of spasticity leading to joint contractures or immobility requiring urgent intervention.
المستشفيات؟ الأسئلة الشائعة حول تحليل
What is the ALS2 gene test used for?
The ALS2 NGS test is a definitive diagnostic tool that identifies disease-causing mutations in the ALS2 gene, providing a molecular confirmation of infantile-onset ascending spastic paralysis with superior sensitivity. This allows early intervention, genetic counseling, and accurate prognosis.
يكشف تحليل جين ALS2 عن الطفرات الممرضة لتأكيد الشلل التشنجي الطفلي الصاعد بدقة تصل إلى 99.9%، مما يساعد في توجيه الرعاية المبكرة والاستشارة الوراثية.
How is the sample collected and what are the requirements?
A certified phlebotomist can collect a venous blood sample at your home, or you may submit a dried blood spot card or previously extracted DNA after completing a mandatory pre-test genetic counseling session to draw a family pedigree.
يتم جمع عينة الدم منزليًا عبر مقدم رعاية معتمد، أو يمكن تقديم بقعة دم جافة أو حمض نووي مستخلص، بشرط إكمال جلسة استشارة وراثية مسبقة.
What is the turnaround time and how will I receive results?
Results are delivered within 3 to 4 weeks of sample receipt at our ISO 9001:2015-accredited laboratory, and a DHA-licensed clinician will provide a telephonic interpretation to explain the findings and recommended next steps.
تُصدر النتائج خلال 3 إلى 4 أسابيع من استلام العينة، مع جلسة تفسير هاتفية من طبيب مرخص لشرح النتائج والخطوات التالية.
This is performed in compliance with Federal Decree-Law No. 41 of 2024 (Medical Laboratories), UAE Child Protection Law (CDS Law 2026 for minors), and UAE PDPL. ISO 9001:2015 Certified Laboratory (Cert: INT/EGQ/2509DA/3139). DHA Facility License: 9834453.
📞 WhatsApp Support & Booking: +971 54 548 8731
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians