Test Price
2,800 AED✅ Home Collection Available
ABCB4 Gene Gallbladder Disease Type 1 Genetic Test in UAE – 2,800 AED | DNA Labs UAE
Executive Summary & Core Metrics
Clinical Diagnostic Confidence & Service Framework
99.9% diagnostic sensitivity via ISO 15189–accredited Next Generation Sequencing (NGS) for targeted ABCB4 gene analysis. VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM across all seven emirates. Includes telephonic post-test clinical guidance from our Consultant Medical Genetics. Direct insurance verification via WhatsApp +971 54 548 8731. Definitive molecular diagnosis enabling tailored hepatology surveillance, family cascade screening, and personalized dietary or pharmacologic management.
Test Overview & Methodology
This genetic test analyzes the ABCB4 gene for pathogenic mutations that cause gallbladder disease type 1, also known as low phospholipid–associated cholelithiasis (LPAC) syndrome. The assay detects single nucleotide variants, insertions, and deletions with 99.9% analytical sensitivity, providing a precise hereditary risk assessment to guide targeted surveillance, prophylactic strategies, and family counselling.
| Feature | Our NGS Test | Standard Imaging Alternative |
|---|---|---|
| Methodology | Next Generation Sequencing (Targeted ABCB4 Analysis) | Abdominal Ultrasound / MRCP |
| Analytical Sensitivity | 99.9% for single nucleotide variants, indels | Limited to structural gallstones; no genetic insight |
| Turnaround Time | 3 – 4 Weeks | Immediate (anatomical findings only) |
| Clinical Utility | Definitive molecular diagnosis, family screening, personalized care | Diagnosis of stones; no genetic risk prediction |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I confirm that molecular analysis of the ABCB4 gene provides definitive diagnostic clarity for patients with unexplained cholelithiasis. A positive finding identifies a hereditary predisposition requiring structured hepatology follow-up, family cascade screening, and personalized dietary management. The results must always be interpreted within the full clinical context and never in isolation.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403.
Advisory – Medication & Clinical Context
⚠ Medicinal Advisory
Do not discontinue prescribed medications such as ursodeoxycholic acid, statins, or supportive supplements without consulting your treating physician. Genetic findings alone do not constitute a medication adjustment order. All therapeutic decisions must be made by a qualified clinician based on complete clinical evaluation.
Safety & Exclusion Criteria
- Exclusion Criteria: Active febrile illness, anticoagulant therapy that cannot be safely paused, pregnancy (requires pre‑test genetic counselling).
- ER Red Flags: Seek immediate emergency care if you experience sudden severe right upper quadrant pain, jaundice, high fever, or persistent vomiting—these may indicate acute cholecystitis or cholangitis, unrelated to the test.
Patient FAQ & Clinical Guidance
1. What is the ABCB4 Gene Gallbladder Disease Type 1 Genetic Test?
This targeted NGS assay detects pathogenic variants in the ABCB4 gene responsible for low phospholipid‑associated cholelithiasis (LPAC syndrome). It provides 99.9% diagnostic accuracy for identifying hereditary predisposition, enabling early surveillance, dietary intervention, and family cascade testing.
2. Who should consider this genetic test?
Patients with recurrent gallstones of unknown etiology, a documented family history of ABCB4‑related disease, or unexplained biliary symptoms should consider testing. A referral from a clinical geneticist or hepatologist is recommended before ordering to ensure pre‑test counselling and appropriate clinical context.
3. Is home sample collection available across the UAE?
Yes, our ISO‑certified phlebotomists provide hospital‑grade VIP Mobile Phlebotomy and Temperature‑Controlled Cold‑Chain Home Collection daily from 8 AM to 11 PM, nationwide. Results are returned within 3–4 weeks with optional post‑test telephonic guidance from a Consultant Medical Genetics.
UAE Regulatory & Data Privacy Adherence
Legal & Compliance Framework
This diagnostic service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical testing, patient consent, and safety protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genetic data is encrypted, access-controlled, and processed solely for diagnostic purposes within DNA Labs UAE’s secure infrastructure.
Clinical & Logistical Metadata
| Test Name | ABCB4 Gene Gallbladder Disease Type 1 Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3 – 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood |
| Methodology Used | Next Generation Sequencing (Targeted ABCB4 Analysis) |
| ICD-10-CM Code | K80.80 |
| LOINC Code | 55233-5 |
| DHA Facility License & Laboratory Address | DHA License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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