Test Price
2,800 AED✅ Home Collection Available
RORC Gene Immunodeficiency Type 42 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل تسلسل الجين RORC للإصابة بنقص المناعة من النوع 42 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
This definitive genetic test sequences the entire RORC gene using high-depth Genetic Test clinical guidance, and direct insurance billing verification via WhatsApp at +971 54 548 8731. Fully compliant with Federal Decree‑Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minors), and UAE PDPL.
ملخص تنفيذي: يقدم هذا التحليل الجيني فحصًا دقيقًا لجين RORC باستخدام تقنية التسلسل الجيني من الجيل التالي (NGS) وفق معايير هيئة الصحة بدبي 2026، مع ضمان حماية البيانات بموجب قانون حماية البيانات الشخصية الإماراتي. دقة تشخيصية تزيد عن 99.9%، مع استشارة وراثية مجانية وخدمة سحب منزلي متميزة.
Test Overview
The RORC NGS test analyses all coding exons and flanking intronic regions of the RORC gene (Immunodeficiency 42) to detect pathogenic/likely pathogenic variants associated with chronic mucocutaneous candidiasis, mycobacterial disease, and autoimmune manifestations. يكشف هذا الفحص الطفرات المرضية في جين RORC بدقة فائقة لتشخيص نقص المناعة من النوع 42.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | 99.9% analytic sensitivity / >99% specificity | Sanger sequencing (single exon, lower variant detection) |
| Method | NGS with full gene coverage & copy number variant analysis | Targeted mutation panel only |
| Turnaround Time | 3–4 weeks | 6–8 weeks |
| Sample Options | Single‑drop blood on FTA card, whole blood, or extracted DNA | Venous blood only |
Physician Insight & Safety Protocol
Dr. Prabhakar Reddy (DHA License: 61713011): “A positive RORC result must be correlated with clinical findings and family history. Genetic diagnosis empowers targeted management and infection prophylaxis, but negative results do not entirely rule out the disorder — comprehensive immunological work‑up is essential.”
Do not discontinue prescribed medication without consulting your doctor. This test requires pre‑test genetic counselling and a detailed pedigree chart.
Safety Exclusion Criteria
- Active severe infection or febrile illness requiring hospitalisation
- Recent (within 30 days) intravenous immunoglobulin therapy (may interfere with immune phenotypic results)
- Inability to provide informed consent or assent for minor patients
- Known bleeding disorder contraindicated for capillary blood collection
Emergency Red Flags After Sample Collection
- Profuse bleeding that does not stop with steady pressure for 10 minutes
- Signs of infection at the puncture site (increasing redness, warmth, pus)
- Sudden fainting, dizziness, or chest pain – call 998 immediately
Patient FAQ & Clinical Guidance
1. What is the RORC Gene Immunodeficiency Type 42 Genetic Test and what does it detect?
Snippet: This advanced NGS test sequences the entire RORC gene to identify pathogenic variants causing primary immunodeficiency type 42, linked to chronic fungal infections and autoimmune conditions. The test covers all coding regions and splice sites, reporting variants classified as pathogenic or likely pathogenic according to ACMG guidelines. It is indicated for individuals with recurrent mucocutaneous candidiasis, severe dermatophyte infections, and suspected Mendelian immunodeficiency. Results help guide long‑term antifungal prophylaxis, immunological follow‑up, and genetic counselling for family members.
يبحث الاختبار في شفرة جين RORC بالكامل للكشف عن الطفرات المسببة لنقص المناعة من النوع 42.
2. Why is this genetic test important for patients with recurrent skin and nail candidiasis?
Snippet: RORC mutations impair IL-17 immunity, leading to chronic mucocutaneous candidiasis, making this test essential for accurate diagnosis and tailored management. Many patients experience years of persistent fungal infections before a definitive genetic diagnosis is established. Identifying a RORC variant justifies targeted therapy, such as antifungal prophylaxis with fluconazole or itraconazole, and screens for associated autoimmune endocrinopathies. Early detection also prevents unnecessary immunosuppressive treatments and allows reproductive counselling.
الطفرات في جين RORC تضعف المناعة المتواسطة بإنترلوكين 17، مما يؤدي إلى عدوى فطرية مزمنة في الجلد والأظافر.
3. كيف تعمل خدمة السحب المنزلي للعينات في الإمارات وما هي المتطلبات؟
Snippet: A certified phlebotomist visits your home between 8 AM and 11 PM to collect a single drop of blood on an FTA card, with cold‑chain transport to our ISO‑lab. You must present a valid Emirates ID and complete a pre‑ genetic counselling session (tele‑health available) that documents a three‑generation pedigree. No fasting is required. For minors, a legal guardian’s consent and identity documents are mandatory as per CDS Law 2026. The FTA card sample remains stable at ambient temperature, and our logistics team ensures immediate ISO‑certified cold‑chain transport upon pickup. Results are delivered through a secure patient portal within 3–4 weeks, with a telephonic clinical interpretation session included.
يزورك أخصائي سحب معتمد بين الساعة 8 صباحًا و 11 مساءً لجمع قطرة دم واحدة على بطاقة FTA، مع نقل مبرد معتمد يلتزم بشروط الأيزو. يجب تقديم بطاقة الهوية الإماراتية وإجراء جلسة استشارة وراثية مسبقة.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians