Test Price
950 AED✅ Home Collection Available
Leucocyte Adhesion Deficiency (LAD I & II) Test in UAE | 950 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO-Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, Available Daily 8 AM – 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in Result Interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Leucocyte Adhesion Deficiency (LAD I & II) Test is a definitive flow-cytometric assay that quantifies CD18 (LAD I) and CD15s (LAD II) expression on leukocytes, enabling early diagnosis of this life-threatening primary immunodeficiency. Early detection guides timely intervention, including bone marrow transplantation or gene therapy.
| Feature | Our LAD Test | Closest Alternative |
|---|---|---|
| Method | Flow Cytometry (quantitative CD18 & CD15s) | Genetic Sequencing (3–7 business days) |
| Precision | 99.9% Diagnostic Sensitivity | Variable; delays clinical action |
| Speed | Next Working Day (sample by 9 AM) | 3–10 working days |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh – Consultant Medical Genetics | DHA Registration ID: 9294403
"As a medical geneticist, I emphasize that the LAD test is a critical tool for early diagnosis of this severe immunodeficiency. However, results must be interpreted alongside complete blood counts and clinical history. A negative flow cytometry result does not exclude all primary immunodeficiencies; persistent symptoms warrant specialist follow-up. Do not delay urgent care while awaiting test results."
Important Advisory
⚠️ Do not discontinue any prescribed medications or supplements without consulting your treating physician. The test result alone does not replace clinical judgment.
Patient Safety: Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients on high-dose systemic corticosteroids (≥1 mg/kg/day) within 48 hours prior to blood draw may have altered leukocyte function, potentially compromising accuracy.
- Exclusion: Infant sample volume less than 2 mL is insufficient and will be rejected.
- Red Flag: If your child exhibits high fever (>39°C), lethargy, difficulty breathing, or signs of septic shock, proceed to the nearest emergency department immediately before scheduling this test.
Patient FAQ & Clinical Guidance
1. What is Leukocyte Adhesion Deficiency?
Leukocyte Adhesion Deficiency is a rare genetic disorder impairing white blood cell movement, leading to recurrent serious infections. This condition results from mutations affecting the CD18 (LAD I) or SLC35C1 (LAD II) genes, causing neutrophils to fail to migrate to infection sites. Early diagnosis through flow cytometry can guide life-saving bone marrow transplantation or gene therapy.
2. How is the LAD test performed and what does it measure?
This test uses flow cytometry to quantify CD18 and CD15s proteins on leukocytes, essential for immune cell adhesion and migration. A small amount of whole blood is collected in two specific tubes (Lavender‑EDTA and Green‑Sodium Heparin) and must be kept at 18–22°C without refrigeration. The laboratory then stains the cells with fluorescent antibodies and analyzes them on a flow cytometer to detect any deficiency.
3. When should I consider the LAD test for my child?
Consider this test if your newborn exhibits delayed umbilical cord separation beyond three weeks, persistent leukocytosis, or recurrent severe infections without pus formation. Other indicators include poor wound healing, omphalitis, and severe gingivitis. Neonatologists and pediatricians often order LAD testing when an infant has unexplained neutrophilia and repeated deep-tissue infections.
UAE Regulatory & Data Privacy Adherence
This service complies with the Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is handled securely and confidentially. Our laboratory operates under DHA Facility License No. 1143 at Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | Leucocyte Adhesion Deficiency (LAD I & II) Test |
| Price (AED) | 950 |
| Turnaround Time | Next Working Day (if sample received by 9 AM) |
| Sample Type / Matrix | Peripheral whole blood (Lavender‑EDTA and Green‑Sodium Heparin) |
| Methodology Used | Flow Cytometry (quantitative CD18 & CD15s) |
| ICD-10-CM Code | D84.8 |
| LOINC Code | 51785-5 |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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