Test Price
2,800 AED✅ Home Collection Available
CYBA Gene (Chronic Granulomatous Disease, Autosomal Recessive, Cytochrome b-Negative) Genetic Test in UAE | 2,800 AED | DHA Approved
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 15189:2012 Accredited NGS Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation, including genetic counseling session.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The CYBA Gene NGS Test comprehensively screens for pathogenic variants in the CYBA gene, confirming autosomal recessive chronic granulomatous disease (CGD) – a primary immunodeficiency characterized by defective neutrophil oxidative burst. Results guide precision therapy, infection prophylaxis, and family risk assessment with a DHA‑approved turnaround of 3–4 weeks.
| Feature | Our Test (NGS) | Closest Alternative |
|---|---|---|
| Precision | Full gene coverage, detection of SNVs, indels, CNVs; analytic sensitivity >99.9% | Selected exon Sanger sequencing; limited variant detection (~85%) |
| Method | Next Generation Sequencing (Illumina®) with bioinformatics verification by ClinGen guidelines | Sanger sequencing, manual interpretation |
| Turnaround Time | 3–4 weeks (home collection available) | 6–8 weeks (in-person draw only) |
Physician Insight & Safety Protocols
“While this NGS test delivers high‑confidence genetic confirmation, it must always be correlated with clinical phenotype, neutrophil function assays, and family history. A positive result empowers early intervention and informed reproductive planning. Please maintain all prescribed prophylactic antimicrobials and immunomodulators until reviewed by a specialist.”
— Dr. Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue prescribed medication without consulting your doctor. Any change in treatment must be guided by a qualified immunologist or hematologist.
Exclusion Criteria & Red Flags
- Consent Requirements: Testing for individuals under 18 years requires documented legal guardian consent as per UAE Personal Data Protection Law (PDPL); unaccompanied minors cannot provide sample.
- Medical Contraindications: Active systemic infection with fever >38.5°C, severe anemia (Hb <7 g/dL), or uncorrected coagulopathy (INR >2.0) must be stabilized before elective phlebotomy.
- Red Flags Post‑Collection: If you experience persistent bleeding, large hematoma, or signs of infection at the puncture site, seek immediate medical attention.
- Laboratory Refusal Rights: Samples not meeting cold‑chain or labeling requirements will be rejected; free recollection will be arranged.
Patient FAQ & Clinical Guidance
1. What is the CYBA gene NGS test used for?
This test detects mutations in the CYBA gene to confirm autosomal recessive chronic granulomatous disease with high precision. It identifies disease‑causing variants, carrier status, and aids in differential diagnosis of primary immunodeficiencies associated with recurrent bacterial and fungal infections.
2. How is the sample collected and what is the turnaround time?
A certified phlebotomist collects a blood sample via VIP Mobile Phlebotomy home visit (available 8 AM – 11 PM), transported under validated cold‑chain conditions. Results are delivered in 3–4 weeks. Alternatively, you can provide extracted DNA or a one‑drop blood sample on an FTA card.
3. Is this covered by UAE health insurance?
We offer direct billing verification via WhatsApp; most UAE insurers cover genetic testing for primary immunodeficiency diagnosis. Contact our support team with your policy details for immediate confirmation and pre‑authorization assistance.
UAE Regulatory & Data Privacy Adherence
This test is fully compliant with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data are encrypted, access‑controlled, and processed under strict confidentiality protocols. Clinical safety and informed consent adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability. The laboratory holds DHA Facility License No. 1143.
Clinical & Logistical Metadata
| Test Name | CYBA Gene (Chronic Granulomatous Disease, Autosomal Recessive, Cytochrome b-Negative) Genetic Test - NGS |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks (21–28 days) |
| Sample Type / Matrix | Peripheral whole blood (EDTA tube) or extracted DNA |
| Methodology Used | Next Generation Sequencing (Illumina®), bioinformatics analysis per ClinGen guidelines |
| ICD-10-CM Code | D71 |
| LOINC Code | 95150-7 |
| DHA Facility License & Laboratory Address | DHA Facility License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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