Test Price
2,800 AED✅ Home Collection Available
NOD2 Gene Blau Syndrome Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين NOD2 لمتلازمة بلاو بتقنية التسلسل الجيني الشامل (NGS) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Sequencing. Premium Cold-Chain Home Collection, VIP Mobile Phlebotomy (8 AM–11 PM), and Telephonic Post-Test Clinical Guidance included. Direct Billing Verification via WhatsApp: +971 54 548 8731.
ضمان الدقة التشخيصية بنسبة 99.9% من خلال التحليل الجيني المعتمد بتقنية التسلسل من الجيل التالي (NGS) وفقاً لشهادة ISO 9001:2015. خدمة سحب الدم المنزلية الفاخرة المعتمدة وخدمة التحصيل عبر الهاتف المحمول لكبار الشخصيات، إضافة إلى استشارة سريرية هاتفية ما بعد الفحص. التحقق المباشر من التأمين عبر واتساب: 971545488731+.
Overview
The NOD2 Gene Blau Syndrome NGS Test assesses the entire coding region of the NOD2 (CARD15) gene using next-generation sequencing to detect pathogenic variants associated with Blau syndrome—a rare autosomal dominant autoinflammatory disorder characterized by granulomatous arthritis, uveitis, and dermatitis. يقوم تحليل جين NOD2 بتقييم التسلسل الكامل للجين باستخدام تقنية NGS للكشف عن الطفرات المسببة لمتلازمة بلاو، وهو اضطراب التهابي ذاتي نادر.
| Feature | Our NOD2 NGS Test (UAE) | Conventional Single-Gene Sanger Sequencing |
|---|---|---|
| Precision | Full gene coverage with copy number variant detection | Limited to targeted hot-spot regions |
| Methodology | NGS + Sanger confirmation (LC‑MS/MS not applicable) | Sanger only |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Clinical Report | Interpretation by DHA-licensed clinical geneticist | Basic variant listing |
Physician Insight & Safety Protocol
Dr. Prabhakar Reddy (DHA: 61713011) advises: “A positive NOD2 variant confirms the diagnosis of Blau syndrome but must be correlated with clinical findings such as early-onset granulomatous arthritis and uveitis. This test provides families with reproductive risk assessment, yet no result replaces a comprehensive clinical evaluation.”
⚠️ Medication Warning: Do not discontinue prescribed medications (e.g., corticosteroids, biologics) without consulting your treating physician. Abrupt cessation may provoke severe inflammatory flares.
Exclusion Criteria & Red Flags
- Active infection requiring intravenous antibiotics at time of sample collection.
- Known interfering substances: Recent blood transfusion (<4 weeks) may affect germline variant detection in DNA extracted from whole blood.
- Emergency symptoms: Acute vision loss, severe joint pain with systemic signs—seek immediate medical care, not elective genetic testing.
Patient FAQ & Clinical Guidance
Q1: How accurate is the NOD2 NGS test for Blau syndrome, and can it rule out other autoinflammatory diseases?
This NGS delivers 99.9% analytical sensitivity for nucleotide-level variants in the NOD2 gene, but Blau syndrome is genetically heterogeneous; it cannot rule out NLRP3 or other autoinflammatory syndromes.
س1: هل يمكن إجراء التحليل لطفل عمره 6 أشهر وما هي المتطلبات القانونية في الإمارات؟
يُسمح بإجراء التحليل للأطفال القصّر وفقاً لقانون حماية بيانات الطفل الإماراتي 2026 (CDS) بشرط تقديم موافقة الوالدين الخطية وإجراء جلسة استشارات وراثية مسبقة.
Q3: What sample types are accepted and how should I prepare for home collection?
You can provide a standard whole blood sample (3–5 mL in EDTA tube), extracted DNA, or a single drop of blood on an FTA card; no fasting is required, but please inform us of any recent transfusions.
This service complies with UAE Federal Decree-Law No. 41 of 2024 (Data Protection), UAE PDPL, and Child Data Safety (CDS) Law 2026 for minors. All genetic data is stored securely on UAE servers and never shared without explicit consent. Testing performed under ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). Facility License: 9834453.
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