Test Price
2,800 AED✅ Home Collection Available
TOR1A Gene (DYT1) Next‑Generation Sequencing – Genetic Diagnostic Test in UAE | AED 2,800 | DHA Licensed
Executive Summary & Core Metrics
Comprehensive Genetic Assessment for Early‑Onset Primary Torsion Dystonia (DYT1)
- Diagnostic Accuracy: 99.9% sensitivity via ISO 9001:2015 accredited NGS platform (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic post‑test interpretation by DHA‑licensed Consultant Medical Genetics.
- Insurance: Direct billing verification via WhatsApp: +971 54 548 8731.
Test Overview & Methodology
The TOR1A gene DYT1 test utilises Next‑Generation Sequencing (NGS) to detect the hallmark GAG deletion (c.907_909delGAG) responsible for early‑onset primary torsion dystonia. This assay is performed under stringent DHA protocols to confirm the clinical diagnosis, assess disease progression risk, and inform family planning through precise genetic counselling. The full coding region and splice sites are analysed, enabling comprehensive mutation detection beyond the common founder variant.
| Feature | TOR1A NGS Test (Our Service) | Closest Alternative – Sanger Sequencing Single‑Gene |
|---|---|---|
| Precision | Full‑gene analysis with copy‑number variant detection | Targets known hotspot only; may miss rare or novel variants |
| Method | Next‑Generation Sequencing – massively parallel, high‑depth coverage | Capillary electrophoresis; lower throughput and sensitivity |
| Turnaround Speed | 21–28 calendar days | Often 28+ days due to batch processing |
| Clinical Utility | Comprehensive – confirms DYT1 and informs at‑risk relatives | Confirmatory only; limited scope for familial variant screening |
Physician Insight & Safety Protocols
“Every genetic result carries profound emotional and clinical significance. Interpretation must be performed within the context of the patient’s personal and family history, ideally in consultation with a qualified neurologist or genetic counsellor. Never base medical decisions on a single laboratory report alone; always correlate with the full clinical picture.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory Notice – Medication Continuity
Important: Do not discontinue any prescribed medication without direct consultation with your treating physician. Abrupt withdrawal may precipitate severe neurological deterioration including dystonic storm or respiratory compromise.
Safety Exclusion Criteria & Emergency Red Flags
- This test is not intended as a stand‑alone diagnostic tool for acute or rapidly progressing neurological decline.
- If you experience sudden muscle rigidity, breathing difficulty, swallowing impairment, or dystonic storm, seek emergency medical attention immediately.
- Minors undergoing testing must be accompanied by a legal guardian who provides informed consent in accordance with Federal Decree‑Law No. 4 of 2016 on Medical Liability.
- All genetic data is stored and processed under the protections of Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Patient FAQ & Clinical Guidance
1. What is the TOR1A gene DYT1 test and what condition does it diagnose?
The TOR1A gene DYT1 test uses Next‑Generation Sequencing to detect the GAG deletion mutation (c.907_909delGAG) that causes early‑onset primary torsion dystonia. The test provides definitive diagnostic confirmation and enables risk assessment for family members who may carry the same mutation.
2. How is the test performed and what sample is required?
A peripheral whole blood sample or a dried blood spot on an FTA card is collected by a certified phlebotomist. DNA is extracted from the specimen and analysed by NGS in an ISO‑accredited laboratory. VIP Mobile Phlebotomy home collection is available daily from 8 AM to 11 PM across Dubai and the Northern Emirates.
3. What is the turnaround time and cost for this test?
Results are typically reported within 21 to 28 calendar days. The total cost is AED 2,800, and insurance direct billing verification can be arranged via WhatsApp at +971 54 548 8731.
4. Will my genetic data remain private and secure?
Yes. All genetic information is handled in full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your data is encrypted, access‑controlled, and never shared without your explicit consent.
5. How should I prepare for the test and what follow‑up is provided?
No special preparation is required. After the test results are issued, a telephonic consultation with a DHA‑licensed Consultant Medical Genetics is included to guide you through the clinical interpretation, implications for family members, and any recommended next steps.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance Framework: This diagnostic service operates under DHA Facility License Number 1143 and adheres to all applicable UAE federal laws. Patient genetic data is protected under Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL). Clinical safety and consent procedures follow Federal Decree‑Law No. 4 of 2016 on Medical Liability, and health data handling practices comply with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Data Privacy: All genomic data is encrypted during transmission and at rest, with strict access controls limited to authorised clinical personnel. No information is disclosed to third parties without the patient’s written informed consent, except where required by UAE law.
Clinical & Logistical Metadata
| Test Name | TOR1A Gene (DYT1) Next‑Generation Sequencing (NGS) |
| Price (AED) | AED 2,800 |
| Turnaround Time | 21–28 Calendar Days |
| Sample Type / Matrix | Peripheral Whole Blood or Dried Blood Spot (FTA Card) – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection Available Daily 8 AM–11 PM |
| Methodology Used | Next‑Generation Sequencing (NGS) – Massively Parallel Sequencing with Full Coding Region & Splice Site Analysis |
| ICD-10-CM Code | G24.1 – Idiopathic Familial Dystonia (DYT1) |
| LOINC Code | 94760-6 – TOR1A gene mutation analysis in Blood by Molecular genetics method |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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