Test Price
2,800 AED✅ Home Collection Available
RNASEH2B Gene Aicardi-Goutières Syndrome Type 2 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين RNASEH2B لمتلازمة أيكاردي-غوتييريس النوع الثاني في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy (8 AM – 11 PM daily).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation with a DHA-licensed neurologist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
الفحص الجيني الدقيق لجين RNASEH2B لتشخيص متلازمة أيكاردي-غوتييريس النوع الثاني، بحساسية تشخيصية تصل إلى 99.9% وفق معايير الآيزو المعتمدة. يشمل استشارة وراثية قبل الفحص، وسحب عينة منزلية مبردة، وإرشاد طبي متكامل بعد النتائج.
This service operates under Federal Decree-Law No. 41 of 2024 (Art. 87) ensuring patient protection and ethical advertising. All genetic data is governed by the UAE Personal Data Protection Law (PDPL). For minors, mandatory guardian consent is obtained per CDS Law 2026. Our facility holds ISO 9001:2015 certification, confirming international quality standards.
Test Overview
This advanced genetic test uses Next‑Generation Sequencing (NGS) to analyse the entire coding region of the RNASEH2B gene, providing a definitive molecular diagnosis for Aicardi‑Goutières Syndrome Type 2 (AGS2). يستخدم هذا الاختبار الجيني المتقدم تقنية التسلسل الجيني من الجيل التالي (NGS) لتحليل كامل المنطقة المشفّرة لجين RNASEH2B، مما يوفر تشخيصًا جزيئيًا قاطعًا لمتلازمة أيكاردي-غوتييريس من النوع الثاني.
| Feature | Our Test | Whole Exome Sequencing |
|---|---|---|
| Method | NGS of RNASEH2B gene only | NGS of all 20,000+ genes |
| Turnaround Time | 3–4 weeks | 6–8 weeks |
| Precision | 99.9% analytical sensitivity & specificity for AGS2 | Lower specificity; high incidental finding risk |
| Clinical Actionability | Direct confirmatory diagnosis & familial screening | Often requires secondary analysis |
| Price | 2,800 AED | 6,500+ AED |
Consultant Neurologist’s Insight – Dr. Prabhakar Reddy
Dr. Prabhakar Reddy, DHA License 61713011: “As a neurologist, I understand the anxiety a family faces when a child presents with unexplained developmental delay and neurological regression. While this genetic test provides definitive molecular confirmation of Aicardi‑Goutières Syndrome Type 2, results must be interpreted in the full clinical context including neuroimaging and CSF interferon-alpha levels. Genetic counselling before and after testing is essential to guide families through the implications of a positive or negative result.”
- This is an elective genetic diagnostic test. It is not intended for acute emergency management.
- Patients with active systemic infections or unstable medical conditions should defer non-urgent genetic testing until stabilised.
- Do not discontinue prescribed medication without consulting your treating physician — genetic results do not replace current treatment plans.
- ER Red Flag: If the patient experiences acute encephalopathy, new‑onset seizures, loss of consciousness, or sudden neurological deterioration, seek emergency care immediately. Do not wait for test results.
Frequently Asked Questions – Clinical Guidance
1. How does this Genetic Test detect Aicardi‑Goutières syndrome type 2?
Snippet answer: This genomic test uses Next‑Generation Sequencing to precisely analyze the RNASEH2B gene, detecting single nucleotide variants, indels, and copy number changes with 99.9% accuracy, enabling a definitive molecular diagnosis.
The assay covers all coding exons and ±20 bp of flanking intronic regions of RNASEH2B. Pathogenic variants, including those missed by older technologies, are identified and confirmed via Sanger sequencing. The result classifies the variant according to ACMG guidelines, directly informing prognosis, familial recurrence risk, and eligibility for clinical trials.
يستخدم هذا الاختبار الجينومي تقنية التسلسل من الجيل التالي لتحليل دقيق لجين RNASEH2B، ويكشف التغيّرات النوكليوتيدية المفردة والإدراج والحذف وتغيرات عدد النسخ بدقة تصل إلى 99.9%، مما يتيح تشخيصًا جزيئيًا قاطعًا.
2. What sample is required and how is the home collection performed?
Snippet answer: You can provide a simple blood sample, extracted DNA, or a finger‑prick dried blood spot on an FTA card, all collected by our VIP mobile phlebotomy team across the UAE.
Our ISO‑certified cold‑chain courier service ensures sample integrity from your doorstep to our genomics lab. The process takes less than 15 minutes, and no fasting is required. A mandatory pre‑test genetic counselling session (telephonic or in‑clinic) is arranged to draw a pedigree chart and document informed consent, in compliance with UAE PDPL.
يمكنك تقديم عينة دم بسيطة، أو حمض نووي مستخلص، أو بقعة دم جافة على بطاقة FTA، ويقوم فريق سحب الدم المتنقل لدينا بجمع العينة من منزلك في جميع أنحاء الإمارات مع الحفاظ على سلسلة التبريد وفق معايير الآيزو.
3. How long until results arrive and what post‑ support is provided?
Snippet answer: Turnaround time is 3–4 weeks; afterwards you receive a comprehensive genetic report reviewed by a consultant neurologist, along with a telephonic counselling session to interpret the results.
The final report details the variant classification, clinical correlation, and actionable recommendations. Our DHA‑licensed specialist will discuss the findings in a scheduled 30‑minute consultation, explaining implications for the patient, siblings, and future pregnancies. Direct billing verification and insurance pre‑approval assistance are available via WhatsApp at +971 54 548 8731.
مدة إنجاز النتيجة من 3 إلى 4 أسابيع؛ بعدها تحصل على تقرير جيني شامل يراجعه استشاري أعصاب، مع جلسة إرشاد هاتفية لتفسير النتائج ووضع الخطوات الطبية اللاحقة.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians