Test Price
2,800 AEDโ Home Collection Available
NDUFAF1 Gene Leigh Syndrome Genetic Test in UAE | 2800 AED | DNA Labs UAE
Executive Summary & Core Metrics
This DHA-licensed genetic test identifies pathogenic variants in the NDUFAF1 gene associated with Leigh syndrome with 99.9% diagnostic sensitivity. Performed via next-generation sequencing with Sanger confirmation, the test supports precise diagnosis, family planning, and clinical management in the UAE.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM โ 11 PM daily).
- Clinical Guidance: Post-test telephonic interpretation by a DHA-licensed consultant medical geneticist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The NDUFAF1 Gene Leigh Syndrome Genetic Test analyzes the complete coding region and splice sites of the NDUFAF1 gene using next-generation sequencing (NGS). All clinically significant variants are confirmed by Sanger sequencing to ensure 99.9% accuracy. The test is indicated for patients with clinical suspicion of mitochondrial disease, particularly Leigh syndrome, and for carrier testing in at-risk families.
| Feature | Our Test (NDUFAF1 NGS) | Closest Alternative |
|---|---|---|
| Methodology | NGS + Sanger confirmation | Microarray/panel without dedicated NDUFAF1 |
| Diagnostic Yield | 99.9% sensitivity for targeted variants | ~85% (depends on panel coverage) |
| Turnaround Time | 3โ4 Weeks | 4โ6 Weeks |
| UAE Insurance Integration | Direct billing verification | Often out-of-pocket |
Physician Insight & Safety Protocols
โAs a consultant medical geneticist, I recognise the significant implications of a Leigh syndrome diagnosis. The NDUFAF1 gene test provides definitive molecular evidence, but results must be integrated with comprehensive neurological evaluation and genetic counselling. Always discuss findings with your treating neurologist before adjusting any therapy.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Note โ Medication and Clinical Management
Do not discontinue any prescribed medication or alter treatment without consulting your doctor. Genetic test results are a supplement to, not a replacement for, ongoing clinical care and emergency management.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Individuals without a documented clinical indication and genetic counselling referral.
- Exclusion: Minors under 18 years without parental/guardian consent as per UAE data protection and medical ethics regulations.
- Exclusion: Patients unwilling to provide informed consent or share relevant family history.
- Red Flag: Seek emergency care (call 998) if the patient develops acute neurological deterioration, respiratory difficulty, or metabolic crisis after sample collection.
- Red Flag: Do not delay urgent medical evaluation based on pending genetic results.
Patient FAQ & Clinical Guidance
1. What is the NDUFAF1 Gene Leigh Syndrome Genetic Test?
It is a next-generation sequencing analysis that identifies pathogenic variants in the NDUFAF1 gene linked to Leigh syndrome with 99.9% diagnostic accuracy. The test requires a blood sample or extracted DNA and is interpreted alongside clinical and family data.
2. Who should consider this genetic test?
Patients with progressive neurological symptoms suggestive of mitochondrial disease, infants with hypotonia/developmental delay, and families with a known NDUFAF1 mutation history should undergo testing under specialist referral. Genetic counselling is mandatory before sample collection.
3. How do I prepare for the test and what is the process?
A genetic counselling session is scheduled first to document a three-generation pedigree; then a blood sample is collected via our home phlebotomy team (8โฏAMโ11โฏPM) under cold-chain conditions. Results are delivered in 3โ4 weeks with a telephonic interpretation session.
UAE Regulatory & Data Privacy Adherence
Legal & Accreditation
Testing complies with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, and Federal Decree-Law No. 4 of 2016 on Medical Liability. Facility licensed by Dubai Health Authority (License No. 1143). Laboratory certified ISO 9001:2015.
Support & WhatsApp: +971 54 548 8731 | Home Collection hours: 8โฏAMโ11โฏPM daily.
Clinical & Logistical Metadata
| Test Name | NDUFAF1 Gene Leigh Syndrome Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA) โ suitable for DNA extraction |
| Methodology Used | Next-Generation Sequencing with Sanger Confirmation |
| ICD-10-CM Code | G31.82 |
| LOINC Code | 101484-1 |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians