Test Price
2,800 AED✅ Home Collection Available
TWNK Gene MTDPS7 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين TWNK لمتلازمة استفاد الحمض النووي للميتوكوندريا النوع السابع (MTDPS7) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity for TWNK mutations via ISO 9001:2015 certified NGS, validated against DHA standards.
- Premium Logistics: Complimentary Hospital‑Grade Home Collection (cold‑chain transport) for venous blood, DNA extraction, or FTA card; VIP Mobile Phlebotomy 8 AM – 11 PM.
- Clinical Guidance: Free telephonic post‑test genetic correlation with a DHA‑licensed genetic counsellor to interpret results.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731. All major UAE networks accepted.
ملخص تنفيذي: يقدم تحليل الجين TWNK بتقنية التسلسل من الجيل التالي (NGS) لتشخيص متلازمة استفاد الحمض النووي للميتوكوندريا النوع السابع بدقة تصل إلى 99.9%، وفق معايير هيئة الصحة بدبي وشهادة الآيزو 9001:2015. يشمل خدمة سحب عينات منزلية بمستوى المستشفيات مع إرشاد وراثي هاتفي بعد النتيجة.
Federal Decree‑Law No. 41 of 2024 (Art. 87), UAE Child Data Safety (CDS) Law 2026, and PDPL fully observed for all genetic data.
Test Overview
The TWNK gene test is a definitive Next‑Generation Sequencing (NGS) analysis for mitochondrial DNA depletion syndrome type 7 (MTDPS7), a severe neurogenetic disorder. It precisely identifies pathogenic variants in the TWNK gene, enabling early clinical intervention, family planning, and tailored neurological management.
| Comparison Factor | Our Test (TWNK NGS) | Closest Alternative (Whole Exome) |
|---|---|---|
| Precision | Full TWNK gene sequencing with >100× coverage; detects SNVs, indels, CNVs | Variable coverage often <30×; may miss deep intronic variants or CNVs |
| Method | Illumina NovaSeq NGS; ISO 9001:2015 validated; DHA‑standard bioinformatics | Generic WES pipelines; incidental findings policy adds complexity |
| Turnaround Time | 3 to 4 weeks (rapid reporting for critical cases) | 6 to 8 weeks, often with longer counselling wait |
Physician Insight & Safety Protocol
“As a DHA‑licensed neurologist, I understand the anxiety of awaiting genetic results for your child’s neurological symptoms. This test provides definitive molecular diagnosis, but it must always be correlated with clinical findings and family history. Do not discontinue any prescribed medication or initiate supplements without consulting your physician.”
— Dr. Prabhakar Reddy, DHA License: 61713011
Safety Exclusion Criteria & ER Red Flags
- Acute severe illness with unstable vital signs – postpone testing until clinically stable.
- Known severe bleeding disorder that contraindicates safe venipuncture – consult haematologist.
- Patient weight below 2.5 kg for venous blood collection – use FTA card or extracted DNA alternative.
- ER Red Flags:
- New‑onset seizures, loss of consciousness, or signs of severe metabolic acidosis (hyperventilation, vomiting) – immediately call 998 or proceed to nearest emergency department.
Patient FAQ & Clinical Guidance
What is the TWNK Gene MTDPS7 test used for?
Identifies TWNK mutations causing mitochondrial DNA depletion syndrome type 7 diagnosis, guiding targeted management. This NGS test confirms pathogenic variants in the TWNK gene, helping distinguish MTDPS7 from other mitochondrial disorders and informing prognosis, enzyme replacement/mitochondrial therapies, and reproductive options.
يحدد التحليل طفرات جين TWNK المسببة لمتلازمة استفاد الحمض النووي للميتوكوندريا النوع السابع، مما يوجه العلاج الدقيق والاستشارة الوراثية.
How is the test performed and what sample is required?
A simple blood draw, DNA extraction, or FTA card drop; completely painless procedure. Our DHA‑licensed phlebotomist collects 2-5 ml of whole blood in an EDTA tube or a single drop on an FTA card, which is stable at room temperature. We also accept previously extracted DNA.
يتم سحب عينة دم بسيطة أو قطرة واحدة على بطاقة FTA، وهي إجراء غير مؤلم تماماً ولا يحتاج إلى تحضير خاص.
What is the turnaround time and cost for this in UAE?
Results in 3–4 weeks, cost 2800 AED with home collection and genetic counselling included. This all‑inclusive price covers home phlebotomy, cold‑chain logistics, NGS analysis, bioinformatics, and a tele‑counselling session. No hidden charges apply.
تصدر النتائج خلال 3 إلى 4 أسابيع، بسعر 2800 درهم شامل السحب المنزلي والاستشارة الوراثية، دون أي رسوم إضافية.
Licensed by Ministry of Health & Prevention (MOHAP) under Facility License: 9834453. All testing adheres to UAE Federal Law No. 41 of 2024 on genetic testing, CDS Law 2026 regarding minors’ data, and PDPL. ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
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التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians