Test Price
2,800 AED✅ Home Collection Available
RNASEH1 Gene Progressive External Ophthalmoplegia with Mitochondrial Deletions Type 2 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل تسلسل الجين RNASEH1 لاعتلال العين الخارجي التدريجي مع حذف الميتوكوندريا من النوع الثاني المتنحي الجسدي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – RNASEH1 Genetic Test
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by specialist panel.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
ملخص تنفيذي – اختبار جين RNASEH1
- دقة تشخيصية مضمونة بنسبة 99.9% عبر معالجة معتمدة من الآيزو.
- خدمة سحب الدم المنزلي الفاخرة والمعتمدة بتقنية سلسلة التبريد.
- إرشاد سريري هاتفي بعد الفحص لتفسير النتائج.
- التحقق المباشر من التأمين عبر واتساب على الرقم +971 54 548 8731.
Test Overview
The RNASEH1 gene NGS test definitively diagnoses autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions type 2 (PEOA2) by analysing the entire coding region and exon-intron boundaries via next-generation sequencing. It serves patients with unexplained ptosis, ophthalmoparesis, and suspected mitochondrial myopathy, delivering a comprehensive genetic report within 3–4 weeks.
| Feature | Our UAE Premium NGS Test | Closest Alternative (Basic NGS Panel) |
|---|---|---|
| Gene Coverage | Complete RNASEH1 gene (all exons, splice sites, CNV analysis) | Partial mitochondrial panel; RNASEH1 may be omitted or not fully covered |
| Methodology | NGS with Sanger confirmation & MLPA for large deletions | NGS only, limited validation |
| Diagnostic Sensitivity | 99.9% | ~85–90% (many variants missed) |
| Turnaround Time | 3–4 weeks | 4–8 weeks |
| UAE DHA Compliance | ✅ Full 2026 DHA/MOHAP adherence | ⚠ May not meet UAE regulatory standards |
Physician Insight & Safety Protocol
“While genetic testing for RNASEH1 is a cornerstone for confirming PEOA2, it must be interpreted together with thorough neurological and ophthalmological clinical findings. A negative result does not exclude other mitochondrial cytopathies, and a positive variant requires careful correlation with family history and dedicated genetic counselling. I encourage patients to view this test as a piece of a larger diagnostic puzzle.”
— Dr. Prabhakar Reddy, Clinical Genetics (DHA License: 61713011)
⚠ Important Safety Notice
Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria (patients should not proceed with blood draw): acute febrile illness, active systemic infection, blood transfusion within the last 2 weeks, inability to provide informed consent, or age <18 years without a legal guardian (in compliance with UAE CDS Law 2026).
Emergency Red Flags: Seek immediate medical attention if you experience sudden double vision, rapidly worsening ptosis, shortness of breath, dysphagia, or palpitations — these may indicate acute neuromuscular compromise.
Patient FAQ & Clinical Guidance
Q1: What exactly does the RNASEH1 gene test diagnose?
A: The RNASEH1 gene test identifies pathogenic mutations responsible for autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions type 2, confirming a precise molecular diagnosis. This genetic diagnosis helps tailor neurological and ophthalmological management, informs prognosis, and enables cascade testing of at-risk family members.
ج: يكشف اختبار جين RNASEH1 عن الطفرات المسببة لاعتلال العين الخارجي التدريجي مع حذف الميتوكوندريا من النوع الثاني المتنحي الجسدي، مما يؤكد التشخيص الجزيئي الدقيق.
Q2: How is the sample collected and is there an age limit for testing?
A: Our VIP phlebotomist collects a standard blood sample from your home using ISO-certified cold-chain procedures; testing is available for patients of all ages with proper consent. For minors, a legal guardian must provide written consent as per Federal Decree-Law No. 41 of 2024 and UAE PDPL. The collected sample is transported under controlled temperature and analysed through NGS within 3–4 weeks.
ج: يتم جمع عينة دم وريدي بسيطة في المنزل عبر ممارس صحي معتمد، باستخدام تقنية سلسلة التبريد المطابقة للمواصفات القياسية؛ الفحص متاح لجميع الأعمار بموافقة ولي الأمر عند الحاجة.
Q3: Will my insurance cover this 2800 AED genetic test in the UAE?
A: Many UAE insurers reimburse the RNASEH1 test when preauthorised; our direct billing verification via WhatsApp at +971 54 548 8731 instantly confirms your coverage. Please have your Emirates ID and insurance card ready. If self-paying, the fee is 2800 AED, inclusive of home collection, genetic counselling, and post- telephonic guidance.
ج: تغطي العديد من شركات التأمين في الإمارات هذا الفحص بعد الحصول على موافقة مسبقة؛ يمكنك التحقق الفوري عبر واتساب على الرقم +971 54 548 8731.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians