Test Price
2,800 AEDโ Home Collection Available
NDUFAF1 Gene Mitochondrial Complex I Deficiency Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Summary: High-precision genetic test for detecting pathogenic variants in the NDUFAF1 gene, linked to mitochondrial complex I deficiency. Fully compliant with DHA regulations, offered with VIP mobile phlebotomy home collection and complimentary post-test telephonic genetic counselling.
โ Diagnostic Accuracy
99.9% diagnostic sensitivity via ISO 9001:2015 accredited NGS processing. Detects single-nucleotide variants, indels, and copy number changes.
๐ Premium Logistics
VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM โ 11 PM. No clinic visit required. FTA card option also supported.
๐ Clinical Guidance
Complimentary telephonic post-test clinical guidance with a DHA-licensed genetic counsellor. Integrated care coordination with your neurologist or geneticist.
๐ณ Insurance & Billing
Direct billing verification available. WhatsApp your insurance card to +971 54 548 8731 for instant confirmation. We accept all major UAE networks.
Test Overview & Methodology
This test uses next-generation sequencing (NGS) to perform comprehensive analysis of the NDUFAF1 gene, identifying pathogenic variants responsible for mitochondrial complex I deficiency (Leigh syndrome, leukoencephalopathy, and neurodevelopmental regression). Our method offers superior diagnostic precision compared to traditional biochemical assays.
| Feature | Our NDUFAF1 NGS Test | Closest Alternative (Biochemical Assay) |
|---|---|---|
| Methodology | Next Generation Sequencing (NGS) โ full gene coverage | Spectrophotometric enzyme activity in muscle biopsy |
| Diagnostic Precision | 99.9% sensitivity for single-nucleotide variants & CNVs | ~70% sensitivity; cannot identify specific gene defects |
| Turnaround Time | 3โ4 Weeks | 6โ8 Weeks (invasive biopsy) |
| Sample Collection | Blood draw at home, FTA card, or extracted DNA โ nonโinvasive | Surgical muscle biopsy under general anaesthesia |
Physician Insight & Safety Protocols
โAs a consultant medical geneticist, I understand the importance of precise molecular diagnosis for mitochondrial disorders. The NDUFAF1 NGS test provides definitive detection of pathogenic variants, but results must be interpreted in the context of clinical phenotype and family history. Always discuss findings with your neurologist or genetic specialist before making any health decisions.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Pre-Test Advisory
A documented clinical history and a pedigree chart of affected family members are required prior to testing. Our DHA-compliant genetic counselling session will be facilitated before sample collection. Do not discontinue any prescribed medication or supplementation without consulting your treating physician. Genetic results do not replace emergency medical care.
Exclusion Criteria
- Active systemic infection โ defer testing until resolved.
- Blood transfusion within 2 weeks โ may cause false results.
- Inability to provide informed consent โ for minors, explicit guardian consent is mandatory under UAE law.
- ER red flags: Sudden loss of consciousness, intractable seizures, acute metabolic acidosis, or stroke-like episodes โ seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What is the NDUFAF1 gene test used for?
This test sequences the entire NDUFAF1 gene to detect pathogenic variants causing mitochondrial complex I deficiency, aiding diagnosis and family planning.
2. How is the sample collected and is it painful?
A certified phlebotomist collects a small blood sample via our VIP mobile phlebotomy service (ISO-certified cold-chain), or you can submit a dried blood spot FTA card. The procedure is minimally invasive and generally painless.
3. When will I receive results and what support is offered?
Results are delivered in 3โ4 weeks with a complimentary post-test telephonic clinical guidance session to explain findings and coordinate further care.
4. Is the test covered by insurance?
We offer direct billing verification with major UAE insurance networks. Send your insurance card via WhatsApp to +971 54 548 8731 for instant confirmation.
UAE Regulatory & Data Privacy Adherence
This test is performed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, stored securely, and never shared without explicit consent. Our laboratory is ISO 9001:2015 certified (INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | NDUFAF1 Gene Mitochondrial Complex I Deficiency Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks (21โ28 business days) |
| Sample Type / Matrix | Peripheral whole blood (or FTA card / extracted DNA) |
| Methodology Used | Next Generation Sequencing (NGS) โ full gene coverage |
| ICD-10-CM Code | E88.49 (Mitochondrial metabolism disorder, other) |
| LOINC Code | 92931-7 (Mitochondrial complex I deficiency mutation detection in Blood or Tissue by Molecular genetics method) |
| DHA Facility License & Laboratory Address | DHA Facility License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians