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Test Price

2,800 AED

✅ Home Collection Available

MT‑TM Gene‑Related Mitochondrial Myopathy NGS Test in UAE | 2800 AED

Executive Summary & Core Metrics

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO‑Accredited Next‑Generation Sequencing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Daily 8 AM – 11 PM). Hospital‑grade sample handling with ISO certified cold‑chain transport.
  • Clinical Guidance: Complimentary Telephonic Post‑Test Genetic Counselling & Result Interpretation.
  • Insurance & Billing: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test provision is fully compliant with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow Federal Decree‑Law No. 4 of 2016 on Medical Liability.

Test Overview & Methodology

This advanced NGS test sequences the entire MT‑TM mitochondrial gene to detect pathogenic variants linked to mitochondrial myopathy and potentially associated cardiomyopathy. The assay provides comprehensive coverage of coding and flanking regions, enabling identification of both known and novel variants with high diagnostic yield.

Feature Our Test (MT‑TM NGS) Closest Alternative (Sanger Sequencing)
Methodology Full‑gene Next‑Generation Sequencing with coverage >99% Targeted mutation analysis by Sanger sequencing
Detection Scope All known & novel variants in MT‑TM (coding + flanking regions) Only pre‑specified known mutations
Turnaround Time 3–4 weeks from sample receipt 4–6 weeks, limited by primer design
Clinical Utility Comprehensive diagnosis, family screening & genetic counselling Confirmation of previously identified familial mutation only

Physician Insight & Safety Protocols

Message from Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA License: 9294403)

Mitochondrial genetic testing yields powerful diagnostic information, yet results must always be interpreted within the full clinical context. I advise every patient to review their report with a certified genetic counsellor before making any medical decisions. This test provides a molecular foundation, but a comprehensive clinical evaluation remains essential for accurate diagnosis and management.

Important Clinical Advisory

Do not discontinue prescribed medication without consulting your doctor. Altering your treatment plan without medical supervision may lead to serious cardiac or metabolic decompensation.

Safety Exclusion Criteria & Emergency Red Flags

  • Exclusion criteria: acute febrile illness, inability to provide a blood or DNA sample, lack of a clinical indication for mitochondrial myopathy testing.
  • Absolute contraindication: genetic testing requested for a minor without documented legal guardian consent as required by UAE Federal Law.
  • Emergency red flags – seek immediate medical attention: sudden severe muscle weakness, breathing difficulty, chest pain, palpitations, or loss of consciousness. These may signal acute mitochondrial crisis or cardiac involvement.
  • Home collection is postponed if the patient presents with any exclusion criterion; rescheduling is free of charge.

Patient FAQ & Clinical Guidance

1. What is MT‑TM gene‑related mitochondrial myopathy?

MT‑TM gene mutations cause mitochondrial myopathy, leading to progressive muscle weakness and possible cardiomyopathy detectable by NGS. The disorder affects energy production in muscle cells, often presenting with exercise intolerance, fatigue, and in some patients, cardiac conduction abnormalities. Our NGS test sequences the entire MT‑TM gene to identify pathogenic variants, enabling precise diagnosis and family risk assessment.

2. How is the NGS test performed and what samples are accepted?

A small blood sample, extracted DNA, or a single drop of blood on an FTA card is all that is required. Our phlebotomist collects the sample during a scheduled home visit using cold‑chain transport. The laboratory then extracts DNA and uses Next‑Generation Sequencing to read every nucleotide of the MT‑TM gene, comparing it against reference sequences to detect clinically significant variants.

3. What will the results tell me and is genetic counselling included?

Your report will indicate if a disease‑causing MT‑TM variant is present, absent, or of uncertain significance, with genetic counselling included. A definite pathogenic finding confirms the diagnosis and helps guide family screening. Variants of uncertain significance (VUS) require clinical correlation and may be reclassified as more data emerge. A complimentary post‑test tele‑counselling session with a certified genetic counsellor is provided to explain every detail.

UAE Regulatory & Data Privacy Adherence

All services at DNA Labs UAE are delivered in strict compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree‑Law No. 4 of 2016 on Medical Liability. Your genetic data is handled with the highest security standards and is never shared without your explicit written consent.

Clinical & Logistical Metadata

Test Name MT‑TM Gene‑Related Mitochondrial Myopathy NGS Test
Price (AED) 2,800 AED
Turnaround Time 3–4 weeks from sample receipt
Sample Type / Matrix Peripheral whole blood, extracted DNA, or FTA card specimen
Methodology Used Next‑Generation Sequencing (NGS) with full‑gene coverage >99%
ICD-10-CM Code G71.3
LOINC Code 81313-5
DHA Facility License & Address License No. 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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