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Test Price

2,800 AED

✅ Home Collection Available

MT-TQ Gene Myopathy Genetic Test in UAE | 2800 AED | DHA-Licensed NGS Diagnostic

Executive Summary & Core Metrics

Clinical Synopsis

  • Diagnostic Sensitivity: 99.9% for pathogenic MT‑TQ variants via ISO 9001:2015‑accredited Next‑Generation Sequencing (NGS).
  • Turnaround Time: 21–28 calendar days from sample receipt to final molecular report.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily from 8 AM to 11 PM.
  • Post‑Test Guidance: Telephonic consultation for result interpretation and genetic counselling.
  • Insurance Support: Direct billing verification via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

The MT‑TQ gene myopathy NGS test sequences the entire mitochondrial MT‑TQ gene to identify pathogenic mutations that cause mitochondrial myopathy and associated neurological disorders. This targeted assay provides a definitive molecular diagnosis, enabling personalised treatment and family risk assessment within the DHA‑regulated UAE healthcare system. The assay employs high‑depth sequencing (minimum 500× coverage) of the mitochondrial genome focused on the MT‑TQ region, ensuring detection of heteroplasmic variants down to 5% allele frequency.

Feature Our MT‑TQ NGS Test Whole Exome Sequencing (Alternative)
Precision Targeted high‑depth NGS of the entire MT‑TQ gene Broad coverage of ~20,000 genes, lower depth for mitochondrial DNA
Turnaround Time 3–4 weeks 6–8 weeks typically
Clinical Specificity >99% for MT‑TQ variants Variable; may miss mitochondrial mutations
Cost‑Effectiveness 2,800 AED, focused on confirmed mitochondrial phenotype Higher price, often requires additional validation

Physician Insight & Safety Protocols

“As a DHA‑licensed Consultant Medical Geneticist, I emphasise that this NGS test offers robust molecular confirmation of MT‑TQ‑associated myopathy. Clinical correlation with electromyography, muscle biopsy, serum creatine kinase levels, and family pedigree remains essential. A positive result confirms the genetic diagnosis but does not forecast disease progression or severity; a negative result does not rule out other mitochondrial or metabolic myopathies. All results must be reviewed with the referring physician for appropriate clinical integration.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory: Medication Stability Protocol

Do not stop, alter, or adjust any prescribed medication — including anticonvulsants, muscle relaxants, cardiac agents, or any metabolic therapies — without direct consultation with your treating physician. Abrupt discontinuation may trigger severe neurological deterioration, cardiac arrhythmia, or metabolic crisis.

Exclusion Criteria & Safety Red Flags

  • Consent: Minors (under 18 years) must have a legal guardian provide informed consent as per Federal Decree‑Law No. 4 of 2016 on Medical Liability; adults unable to consent require a legally authorised representative.
  • Emergency Indicators: Sudden severe muscle weakness, difficulty breathing, choking, or irregular heartbeat require immediate emergency medical attention — do not wait for test results.
  • Pregnancy/Lactation: Genetic testing may be performed but requires additional pre‑ and post‑test genetic counselling.

Patient FAQ & Clinical Guidance

1. What is the MT‑TQ gene and how does it cause myopathy?

The MT‑TQ gene encodes a mitochondrial transfer RNA essential for producing proteins that power muscle cells; harmful mutations disrupt energy production, causing progressive muscle weakness and neurological symptoms such as exercise intolerance, ptosis, and ophthalmoparesis. This test detects those mutations with high sensitivity.

2. How is the sample collected and what is the turnaround time?

Our VIP Mobile Phlebotomy service collects a standard peripheral whole blood sample (two EDTA tubes, 5 mL each) at your home between 8 AM and 11 PM daily, using temperature‑controlled cold‑chain transport. Alternatively, an existing extracted DNA sample or FTA card may be accepted. Results are delivered within 21–28 calendar days.

3. Is the test covered by UAE insurance and what is the total cost?

The MT‑TQ NGS test is priced at 2,800 AED. Many UAE health insurers cover genetic testing when prior approval is obtained. Contact us on WhatsApp at +971 54 548 8731 for direct billing verification and assistance with your insurance claim.

4. What does a positive or negative result mean for my family?

A positive result confirms a pathogenic MT‑TQ variant and enables cascade testing for at‑risk maternal relatives. A negative result reduces but does not eliminate the possibility of mitochondrial myopathy — other nuclear or mitochondrial genes may be involved. Genetic counselling is provided to discuss recurrence risks and reproductive options.

UAE Regulatory & Data Privacy Adherence

Data Protection & Legal Compliance

  • Health Data Privacy: All genetic data is processed in full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
  • Medical Liability & Consent: Clinical testing safety and patient consent adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability.
  • Quality Certification: ISO 9001:2015 Certified — Certificate No. INT/EGQ/2509DA/3139.
  • Institutional Oversight: Corporate Lab Branding: DNA Labs UAE. Medical Director: Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403.

Clinical & Logistical Metadata

Test Name MT‑TQ Gene Myopathy NGS Test
Price (AED) 2,800 AED
Turnaround Time 21–28 calendar days
Sample Type / Matrix Peripheral whole blood (two EDTA tubes), extracted DNA, or FTA card
Methodology Used Next‑Generation Sequencing (NGS) — targeted high‑depth mitochondrial genome sequencing (minimum 500× coverage)
ICD‑10‑CM Code G71.3
LOINC Code 85439‑0
DHA Facility License & Address License No. 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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