Test Price
2,800 AED✅ Home Collection Available
MT-ND6 Gene Mitochondrial Complex I Deficiency Genetic Test in UAE | 2,800 AED | 2026 DHA Guidelines
تحليل جين MT-ND6 وعوز المركب المتقدرة الأول في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – Guarantee of Diagnostic Excellence
- Accuracy: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert. INT/EGQ/2509DA/3139).
- Premium Logistics: Hospital-Grade Home Collection (8 AM–11 PM) with ISO-Certified Cold-Chain transport for DNA stability.
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Interpretation with a DHA-licensed Genetic Counsellor.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
الملخص التنفيذي – ضمان التميز التشخيصي
- الدقة: 99.9% حساسية تشخيصية وفق معايير ISO 9001:2015.
- الخدمات المتميزة: جمع عينات منزلية بمعايير المستشفيات (8 ص–11 م) مع سلسلة تبريد معتمدة.
- الإرشاد السريري: استشارة ما بعد الفحص عبر الهاتف مع مستشار وراثي مرخص من هيئة الصحة بدبي.
- التأمين: التحقق المباشر من التغطية التأمينية عبر واتساب +971545488731.
Overview: Precision Diagnosis for Mitochondrial Complex I Deficiency
This advanced Next-Generation Sequencing (NGS) test targets the MT-ND6 gene, a critical subunit of mitochondrial respiratory chain complex I. Mutations cause severe neurological disorders, including Leigh syndrome and MELAS. With a turnaround time of 3-4 weeks, our UAE-based ISO-certified facility delivers high-depth sequencing and expert interpretation aligned with 2026 DHA and international guidelines.
هذا الفحص المتقدم باستخدام التسلسل الجيني عالي الإنتاجية (NGS) يستهدف جين MT-ND6، أحد المكونات الأساسية لمعقد سلسلة التنفس المتقدرية الأول. الطفرات تسبب اضطرابات عصبية وخيمة تشمل متلازمة لي وMELAS.
Why Our Test Surpasses Alternatives
| Feature | Our MT-ND6 NGS Test | Whole Exome Sequencing (WES) |
|---|---|---|
| Diagnostic Precision | 99.9% sensitivity for MT-ND6 variants | ~95% coverage, risk of incidental findings |
| Methodology | Deep NGS with mitochondrial-specific bioinformatics | Broad exonic capture, may miss mtDNA variants |
| Turnaround | 3-4 weeks | 6-8 weeks |
| UAE Compliance | Full adherence to PDPL, DHA Genetic Testing Laws 2026 | May require additional consent for incidental findings |
Clinical Utility & Referral Pathways
This test is primarily ordered by three specialists:
- Consultant Neurologist: For confirming mitochondrial aetiology in unexplained neurological regression, seizures, or stroke-like episodes.
- Clinical Geneticist: For cascade screening, family planning, and interpretation of mitochondrial inheritance patterns.
- Paediatric Neurologist: For early-onset phenotypes in neonates and children, guiding management per CDS 2026 minor consent protocols.
Physician Insight & Safety Protocol
"This genetic analysis must be correlated with clinical and biochemical findings. A negative result does not exclude mitochondrial dysfunction from other genes. We emphasise that no test replaces a thorough neurological evaluation."
— Dr. PRABHAKAR REDDY, DHA License No. 61713011, Senior Consultant Neurologist
⚠ Medication Warning
Do not discontinue any prescribed medication without consulting your treating physician. Abrupt cessation of anticonvulsants or mitochondrial support supplements can precipitate acute deterioration.
Exclusion Criteria & ER Red Flags
- Not suitable for asymptomatic individuals without a family history—consult a genetic counsellor.
- If you experience: sudden loss of consciousness, unremitting seizures, severe lactic acidosis symptoms (vomiting, rapid breathing), seek emergency care immediately.
- This test cannot rule out all mitochondrial disorders or non-genetic causes of neurological decline.
Frequently Asked Questions (FAQ)
What is the diagnostic value of MT-ND6 gene testing in mitochondrial disorders?
Snippet Answer: MT-ND6 NGS testing identifies pathogenic variants with 99.9% sensitivity, enabling precise diagnosis of complex I deficiency syndromes such as Leigh syndrome, MELAS, and adult-onset dystonia.
The assay sequences the entire MT-ND6 coding region and flanking mitochondrial DNA regions, using 2026-validated bioinformatics to differentiate heteroplasmy levels, which directly correlate with disease severity.
ما القيمة التشخيصية لفحص جين MT-ND6 في الاضطرابات المتقدرية؟
يحدد فحص تسلسل الجين MT-ND6 الطفرات الممرضة بدقة 99.9%، مما يتيح تشخيصًا دقيقًا لحالات عوز المعقد الأول مثل متلازمة لي وMELAS واختلال التوتر البادئ عند البالغين.
How is the sample collected, and what is the turnaround time?
Snippet Answer: A single blood draw (3 mL in EDTA tube) or a dried blood spot on an FTA card is collected via home phlebotomy service, with results ready in 3 to 4 weeks.
Home collection is performed by DHA-licensed nurses from 8 AM to 11 PM, using ISO-certified cold-chain kits. Extraction of DNA from whole blood guarantees high-quality starting material for NGS.
كيف تُجمع العينة وما المدة الزمنية اللازمة للنتيجة؟
يتم جمع عينة دم واحدة (3 مل في أنبوب EDTA) أو بقعة دم جافة على بطاقة FTA عن طريق خدمة الفصد المنزلي، وتصدر النتائج خلال 3 إلى 4 أسابيع.
Is this genetic covered by UAE health insurance?
Snippet Answer: Most UAE insurers cover MT-ND6 analysis when pre-authorized by a neurologist; direct billing and eligibility checks are available via WhatsApp at +971 54 548 8731.
We coordinate with all major networks (Daman, AXA, Neuron, etc.) following PDPL privacy standards. A genetic counselling session is often required for authorisation.
هل يتم تغطية هذا الفحص الجيني من التأمين الصحي في الإمارات؟
معظم شركات التأمين في الإمارات تغطي تحليل MT-ND6 بعد موافقة طبيب الأعصاب؛ يمكنك التحقق من الأهلية وإرسال الفواتير عبر واتساب على الرقم +971545488731.
Regulatory Compliance: This service abides by Federal Decree-Law No. 41 of 2024 (Article 87) on Genetic Testing, the Child Data Safety (CDS) Law 2026 for minors, and UAE Personal Data Protection Law (PDPL). ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). Facility License: 9834453. All genetic data is processed in UAE-based servers with encryption.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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