Test Price
2,800 AEDโ Home Collection Available
MFF Gene Mitochondrial Encephalomyopathy Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Clinical Certainty: This NGS-based genetic test delivers 99.9% Diagnostic Sensitivity for pathogenic variants in the MFF gene associated with mitochondrial encephalomyopathy, processed through ISO 9001:2015 certified laboratory protocols (Cert: INT/EGQ/2509DA/3139). Every result undergoes dual-clinician verification before release.
- โPremium Logistics: Hospital-Grade Home Collection via ISO-Certified Cold-Chain Phlebotomy โ 8 AM to 11 PM, 7 days across all UAE Emirates.
- โVIP Mobile Phlebotomy: DHA-licensed phlebotomists dispatched to your home, office, or hotel within 60 minutes.
- โTelephonic Post-Test Clinical Guidance: Complimentary 15-minute result interpretation session with a clinical genetic counsellor.
- โInsurance Direct Billing: Verify coverage via WhatsApp at +971 54 548 8731 โ response within 15 minutes.
Test Overview & Methodology
The MFF Gene Mitochondrial Encephalomyopathy Genetic Test is a comprehensive next-generation sequencing analysis that screens the entire coding region of the MFF (Mitochondrial Fission Factor) gene for pathogenic single nucleotide variants, small insertions/deletions, and copy number variations associated with mitochondrial encephalomyopathy โ a progressive neurological disorder affecting cellular energy metabolism. This test is indicated for patients presenting with unexplained neuromuscular degeneration, seizures, developmental regression, or suspected mitochondrial disease, and serves as a definitive molecular diagnostic tool for neurologists, clinical geneticists, and researchers across the UAE.
| Feature | Our NGS Test (MFF Gene) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Diagnostic Sensitivity | 99.9% (full gene coverage + CNV detection) | ~95% (exon-by-exon only; misses large deletions) |
| Methodology | NGS (Next Generation Sequencing) with LC-MS/MS orthogonal validation | Capillary Electrophoresis Sanger Sequencing |
| Turnaround Time | 3 to 4 Weeks | 6 to 8 Weeks (fragmented workflow) |
| Pre-Test Genetic Counselling | Included โ pedigree charting + risk assessment | Often not included |
| Sample Types Accepted | Whole Blood, Extracted DNA, or One Drop Blood on FTA Card | Whole Blood only (venous draw required) |
Physician Insight & Safety Protocols
Clinical Note from Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA License: 9294403) โ Identifying a pathogenic variant in the MFF gene provides a definitive molecular diagnosis for mitochondrial encephalomyopathy, but it is essential to correlate this with neuroimaging, biochemical profiles, and detailed family pedigree. I encourage patients and referring physicians to view this result as a step toward tailored management and carrier screening for at-risk relatives. Our team is committed to guiding you through every implication of your genetic findings.
โ Critical Medication Notice
Do not discontinue, modify, or adjust any prescribed medication โ including anticonvulsants, mitochondrial cofactor supplements (CoQ10, L-Carnitine, Riboflavin), or any neurological therapy โ without explicit consultation with your treating neurologist. Abrupt medication changes in mitochondrial disorders may precipitate metabolic crisis or seizure exacerbation.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria (Do Not Proceed with Home Collection If:)
- Patient is under 18 years of age without a legal guardian present to provide informed consent.
- Patient has a known severe coagulopathy, active bleeding disorder, or platelet count below 50,000/ยตL.
- Patient is currently experiencing an acute neurological crisis (status epilepticus, stroke-like episode, or altered consciousness).
- Patient is unable to provide voluntary informed consent and no legally authorized representative is available.
Emergency Red Flags โ Seek Immediate Medical Attention If:
- Sudden onset of severe, intractable headache with vomiting (risk of stroke-like episode).
- New-onset seizures or significant change in seizure frequency/intensity.
- Acute visual loss, ophthalmoplegia, or ptosis.
- Rapid neurological deterioration, loss of ambulation, or respiratory muscle weakness.
- Unexplained lactic acidosis with altered mental status.
Patient FAQ & Clinical Guidance
1. What is the MFF Gene Mitochondrial Encephalomyopathy NGS Test, and why is it recommended for suspected mitochondrial disease?
This advanced genetic test sequences the entire MFF gene using Next Generation Sequencing (NGS) to detect pathogenic variants. It is recommended when clinical presentation includes progressive neurological decline, seizures, muscle weakness, or developmental regression without a clear etiology. By pinpointing the exact genetic variant, neurologists can confirm diagnosis, guide targeted therapy, and inform family planning decisions.
2. How long will results take, what is the total cost in the UAE, and is insurance accepted?
Results are delivered within 3 to 4 weeks at a total cost of 2800 AED inclusive of pre-test genetic counselling, sample collection, and post-test clinical guidance. We offer direct insurance billing verification โ simply send your insurance card via WhatsApp to +971 54 548 8731 and our team will confirm coverage within 15 minutes. The price covers the complete NGS workflow including orthogonal validation of any detected variants using confirmatory methods, ensuring the highest diagnostic accuracy available in the UAE market.
3. Is home sample collection available across all UAE emirates and what sample types are accepted?
Yes, our ISO 9001:2015 certified home collection service operates from 8 AM to 11 PM daily across all seven emirates including Dubai, Abu Dhabi, Sharjah, Ajman, Umm Al Quwain, Ras Al Khaimah, and Fujairah. We accept three sample types for maximum flexibility: standard venous whole blood draw, previously extracted DNA, or a single drop of blood on an FTA card โ making this test accessible even for patients with difficult venous access or those requiring pediatric collection. Our phlebotomists are DHA-licensed and trained in cold-chain transport protocols, ensuring sample integrity from collection to laboratory processing.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance: This test and its associated data handling fully comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for the UAE, ensuring your genetic and personal data are stored, processed, and transmitted with the highest security standards. Additionally, our laboratory operations adhere to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, guaranteeing secure electronic health records and telemedicine integrations. All clinical procedures, including informed consent and patient safety, are conducted in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Privacy Assurance: Your genetic information is protected under UAE law and is never shared without your explicit written consent. DNA Labs UAE is a DHA-licensed facility (License No. 1143) committed to maintaining the confidentiality and integrity of your health data.
Clinical & Logistical Metadata
| Test Name | MFF Gene Mitochondrial Encephalomyopathy Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or FTA Card (One Drop Blood) |
| Methodology Used | Next Generation Sequencing (NGS) with Orthogonal Validation (LC-MS/MS) |
| ICD-10-CM Code | G71.3 |
| LOINC Code | 62896-9 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
DNA Labs UAE. All results must be interpreted by a qualified healthcare professional. This page does not constitute medical advice.
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