Test Price
2,800 AED✅ Home Collection Available
FOXRED1 Gene Genetic Test in Dubai | 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO‑accredited Next‑Generation Sequencing (NGS) and orthogonal Sanger confirmation of all clinically reportable variants.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic post‑test counselling by board‑certified genetic counsellors – clear interpretation and next‑step planning.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731; liaison with all major UAE insurers.
- Turnaround Time: 3–4 weeks from sample collection.
Test Overview & Methodology
The FOXRED1 gene encodes a mitochondrial complex I assembly factor. Biallelic pathogenic variants cause mitochondrial complex I deficiency, most commonly presenting as Leigh syndrome (subacute necrotising encephalomyelopathy). Our assay sequences all coding exons and flanking splice‑site regions via Next‑Generation Sequencing on the Illumina NovaSeq platform, with Sanger confirmation of any pathogenic, likely pathogenic, or variant of uncertain significance. This approach detects single‑nucleotide variants, small insertions/deletions, and copy‑number changes with >99.9% analytical sensitivity for SNVs.
| Parameter | DNA Labs UAE FOXRED1 NGS | Typical Alternative (Targeted Sanger) |
|---|---|---|
| Coverage | All coding exons + 20 bp intronic flanks; CNV detection | Single exon only |
| Analytical Sensitivity | >99.9% for SNVs, >95% for CNVs | ~95% for SNVs; CNVs missed |
| Turnaround Time | 3–4 weeks | 5–6 weeks |
| Methodology | NGS + Sanger confirmation | Sanger only |
Physician Insight & Safety Protocols
Clinical Note from Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA: 9294403): FOXRED1‑related mitochondrial disease is a severe, often early‑onset neurometabolic disorder. A negative NGS result for this gene does not exclude other mitochondrial defects; any identified variant of uncertain significance must be evaluated by a multidisciplinary team including a neurologist and clinical geneticist. Always correlate molecular findings with the patient’s clinical and biochemical profile.
Advisory: Medications and Testing
Do not discontinue any prescribed medication without consulting your doctor. Certain drugs may affect laboratory results; inform our phlebotomist of all current medications.
Exclusion Criteria & Red Flags
- Exclusion: Blood transfusion or allogeneic bone‑marrow transplant within the past 3 months – may introduce donor‑derived DNA and confound results.
- Exclusion: Active immunosuppressive therapy that could alter lymphocyte DNA; medical history must be verified prior to collection.
- Emergency Red Flags – proceed to nearest ER immediately if: Acute loss of consciousness, seizures unresponsive to rescue medication, severe metabolic acidosis, or respiratory failure.
Patient FAQ & Clinical Guidance
1. What does a negative FOXRED1 NGS result mean for my child’s mitochondrial symptoms?
A negative result rules out pathogenic variants in this specific gene but does not exclude mitochondrial disease caused by other genes. Further genetic and biochemical investigation is mandatory.
2. How long does it take to receive the test report and what does it include?
The final clinical report is delivered within 3–4 weeks. It includes a detailed interpretation of detected variants, zygosity, in‑silico predictions, and ICD‑10‑CM / gene‑phenotype correlations.
3. Is this test covered by UAE health insurance policies?
Many UAE insurers cover FOXRED1 NGS when prescribed by a neurologist or clinical geneticist. Our team provides free direct billing verification via WhatsApp +971 54 548 8731 before sample collection.
UAE Regulatory & Data Privacy Adherence
- DHA Facility License: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
- Data Privacy: Fully compliant with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 concerning the use of ICT in health fields.
- Medical Liability: Patient consent and safety protocols adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability.
- Accreditation: ISO 9001:2015 certified for quality management; all genetic testing performed in CAP‑accredited laboratories.
Clinical & Logistical Metadata
| Test Name | FOXRED1 Gene Genetic Test (NGS & Sanger) |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral Blood (Whole Blood) in EDTA |
| Methodology Used | Next‑Generation Sequencing (Illumina NovaSeq) + Sanger confirmation |
| ICD-10-CM Code | G31.82, E88.40, Z13.71 |
| LOINC Code | 98569-1 |
| DHA Facility License & Address | 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians