Test Price
2,800 AED✅ Home Collection Available
FASTKD2 Gene – Mitochondrial Complex IV Deficiency Genetic Test (NGS) in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين FASTKD2 – نقص المركب الرابع في الميتوكوندريا في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Clinical Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO-Certified Cold-Chain and VIP Mobile Phlebotomy.
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Interpretation by DHA-Licensed Neurologist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731 (within 2 hours).
الملخص التنفيذي السريري
- ضمان الدقة: حساسية تشخيصية بنسبة 99.9% عبر معالجة معتمدة بمعيار ISO 9001:2015 (شهادة: INT/EGQ/2509DA/3139).
- الخدمات اللوجستية المتميزة: خدمة سحب الدم المنزلي بمستوى المستشفى عبر النقل المبرد المعتمد بمعايير ISO.
- الإرشاد السريري: استشارة هاتفية مجانية بعد الاختبار من طبيب أعصاب مرخص من هيئة الصحة بدبي.
- التأمين: التحقق المباشر من التغطية التأمينية عبر واتساب +971 54 548 8731 (خلال ساعتين).
UAE Regulatory Compliance: Federal Decree-Law No. 41 of 2024 (Art. 87 – Medical Liability); CDS Law 2026 (Minors); UAE PDPL (Data Privacy).
Facility License: 9834453 | Support: +971 54 548 8731 (WhatsApp 24/7).
Test Overview
The FASTKD2 Gene test leverages Next-Generation Sequencing (NGS) to detect pathogenic variants causing Mitochondrial Complex IV (Cytochrome c Oxidase) Deficiency – a severe neurometabolic disorder with early-onset neurological decline. Designed for UK/UAE patients, this definitive genetic analysis enables precise diagnosis, family cascade screening, and personalized therapeutic strategies under one robust DHA-compliant workflow.
يستخدم فحص جين FASTKD2 تقنية تسلسل الجيل التالي (NGS) للكشف عن الطفرات المرضية المسببة لنقص المركب الرابع (سيتوكروم سي أوكسيداز) في الميتوكوندريا – وهو اضطراب عصبي استقلابي وخيم. يوفّر هذا التحليل الجيني القاطع تشخيصاً دقيقاً وفحصاً عائلياً واستراتيجيات علاجية مخصصة في إطار متوافق مع متطلبات هيئة الصحة بدبي.
| Feature | Our FASTKD2 NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision (Analytical Sensitivity) | >99.9% – Deep coverage of entire coding region | ~95% – Limited to selected exons |
| Methodology | Next Generation Sequencing (NGS) with CNV analysis | Capillary (Sanger) bidirectional sequencing |
| Turnaround Time | 3 – 4 Weeks | 4 – 6 Weeks |
| Variant Detection | SNVs, indels, deep intronic splice sites, large deletions/duplications | Mainly SNVs and small indels |
| Sample Flexibility | Blood, Extracted DNA, One-drop Blood on FTA Card | Whole blood or purified DNA |
Physician Insight & Safety Protocol
Note from Dr. PRABHAKAR REDDY (DHA License: 61713011), Consultant Neurologist
“As a neurologist, I deeply understand the uncertainty families face when a mitochondrial disorder is suspected. This test provides strong molecular evidence, but it must be correlated with clinical presentation and pedigree data. Treatment decisions should never rely on a single result. My team and I are here to guide you through every step of the diagnostic journey.”
⚠️ Critical Clinical Warning:
Do not discontinue any prescribed medication, supplements, or mitochondrial cocktail therapy without explicit instruction from your treating physician. Abrupt cessation can precipitate metabolic decompensation.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients experiencing acute encephalopathic crisis or active seizure within 48 hours prior to collection.
- Minors: Must have documented informed parental consent (CDS Law 2026); testing of asymptomatic minors without clinical justification is strongly discouraged.
- Anticoagulation: Individuals on high-dose anticoagulants (e.g., warfarin, heparin) require written clearance from the managing physician for venipuncture.
- Emergency Red Flags – Seek Immediate Hospital Care, Not At-Home Testing: Sudden loss of consciousness, uncontrolled seizures, acute respiratory distress, or severe lactic acidosis symptoms.
Patient FAQ & Clinical Guidance
1. What is the FASTKD2 gene test and when is it indicated?
Snippet: The FASTKD2 gene test definitively identifies pathogenic mutations in the FASTKD2 gene responsible for mitochondrial complex IV deficiency, a neurometabolic disorder. يحدد فحص جين FASTKD2 الطفرات المرضية المسؤولة عن نقص المركب الرابع في الميتوكوندريا، وهو اضطراب عصبي استقلابي. Clinical indications include unexplained neurological regression, failure to thrive, hypotonia, and suspected Leigh-like syndrome; it is often ordered by Consultant Neurologists or Clinical Geneticists after metabolic screening.
2. How is the sample collected and what is the wait time for results?
Snippet: A simple blood draw, one-drop blood on an FTA card, or previously extracted DNA is collected via ISO-certified cold-chain home phlebotomy. يتم جمع عينة الدم أو نقطة دم على بطاقة FTA أو الحمض النووي المستخلص عبر خدمة السحب المنزلي المبردة والمعتمدة. The analysis requires 3–4 weeks because of extensive sequencing, bioinformatic interpretation, and two-clinician validation; you will receive a secure, DHA-format report.
3. Is the FASTKD2 test covered by insurance in the UAE, and how do I confirm?
Snippet: Direct billing verification is processed instantly when you share your policy details via WhatsApp at +971 54 548 8731. يتم التحقق المباشر من التغطية التأمينية فوراً عند مشاركة تفاصيل وثيقتك عبر واتساب على الرقم +971 54 548 8731. We collaborate with major UAE insurers; pre-authorization is completed within 2 hours, and you only pay the non-covered portion, if any.
Pre- Requirements & Genetic Counselling
- A mandatory genetic counselling session will be arranged to record a detailed pedigree of affected family members.
- Please provide complete clinical history, including prior metabolic screens, neuroimaging reports, and current medication list.
- No fasting is required, but stay well-hydrated. Avoid alcohol or high-dose vitamin supplements 24 hours before sampling (may interfere with metabolic markers).
- Minors must be accompanied by a legal guardian with valid Emirates ID and consent form.
- For one-drop FTA card collection, follow the instructional video sent upon booking.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians