Test Price
2,800 AED✅ Home Collection Available
COX15 Gene Leigh Syndrome Genetic Test in Dubai, UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This Next-Generation Sequencing (NGS) test thoroughly evaluates the entire coding region of the COX15 gene to identify pathogenic variants linked to Leigh syndrome—a severe mitochondrial neurological disorder often presenting in infancy. Our method provides comprehensive analysis including exons and splice sites.
| Feature | Our COX15 NGS Test | Standard Targeted Mutation Panel |
|---|---|---|
| Methodology | NGS – Full Gene Sequencing (exons + splice sites) | PCR-based selected hotspot analysis |
| Variant Detection | 99.9% – includes novel, rare, & structural variants | Only known common mutations (~60% yield) |
| Turnaround | 3 to 4 Weeks | 2 to 3 Weeks |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh – Consultant Medical Genetics (DHA ID: 9294403) notes: “This COX15 gene sequencing test offers precise molecular confirmation when clinical and imaging findings suggest Leigh syndrome. As a clinical geneticist, I emphasize that results must be interpreted alongside a thorough family history and metabolic workup. The test is a powerful tool for guiding genetic counseling and management but should not be used in isolation.”
Medication and Treatment Advisory
⚠️ Do not discontinue or modify any prescribed medications without consulting your physician. Always seek medical advice before altering treatment based on test results.
Exclusion Criteria & Emergency Red Flags
- Blood draw contraindications: Severe coagulopathy, active infection at the puncture site, or inability to obtain venous access in critically ill neonates.
- FTA card collection note: For infants < 1.5 kg or with fragile skin, a heel-prick micro-sample may be preferred under medical supervision.
- 🚨 ER Warning: If your child experiences acute respiratory distress, intractable seizures, or sudden loss of consciousness, seek immediate emergency care—these are not related to sample collection but may indicate Leigh syndrome progression.
Patient FAQ & Clinical Guidance
1. What is the COX15 Gene Leigh Syndrome Genetic Test?
This Next-Generation Sequencing test detects pathogenic variants in the COX15 gene associated with Leigh syndrome, a severe mitochondrial neurological disorder. It provides a definitive molecular diagnosis when clinical and imaging findings are suggestive, enabling precise genetic counseling and personalized management.
2. How is the sample collected, and is it safe for my child?
A DHA-licensed phlebotomist collects a small blood sample via a gentle finger prick onto an FTA card during a home visit. Alternatively, a whole blood sample or previously extracted DNA can be used. The process is minimally invasive and performed under strict safety protocols. A genetic counseling session is arranged prior to collection to draw a family pedigree and obtain informed consent, in compliance with Federal Decree-Law No. 4 of 2016 on Medical Liability and UAE Personal Data Protection Law (PDPL).
3. What do the results mean and what are the next steps?
A positive result confirms a COX15 gene mutation causing Leigh syndrome, necessitating specialist genetic counseling and multidisciplinary care. A negative result reduces probability but does not entirely exclude a mitochondrial disorder. Every result is reviewed by our team; you will receive a telephonic explanation and a detailed report guiding you to the appropriate neurologist or metabolic specialist for further clinical correlation.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is encrypted, stored securely, and handled with confidentiality. For clinical safety and patient consent, we follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Our DHA facility license (1143) ensures full compliance with Dubai Healthcare City regulations.
Clinical & Logistical Metadata
| Test Name | COX15 Gene Sequencing for Leigh Syndrome |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood (Peripheral) or FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) – Full Gene Sequencing |
| ICD-10-CM Code | G31.82 (Leigh Syndrome) |
| LOINC Code | 21677-0 (Gene mutations detected in Blood or Tissue by Sequencing) |
| DHA Facility License & Laboratory Address | License #1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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