Test Price
1,200 AED✅ Home Collection Available
JAK2 Mutation Detection Panel (Exons 12-15) in UAE | 1200 AED | 2026 DHA Guidelines
تحليل لوحة الكشف عن طفرات جاك 2 (إكسونات 12-15) في الإمارات | 1200 درهم | معتمد من هيئة الصحة بدبي
الملخص التنفيذي
يضمن تحليل جاك 2 (الإكسونات 12-15) دقة تشخيصية فائقة بنسبة 99.9% عبر مختبرنا المعتمد آيزو 9001، مع إمكانية السحب المنزلي الفاخر والتوجيه السريري بعد النتيجة.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: Hospital‑Grade Home Collection with ISO‑Certified Cold Chain and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance for expert interpretation of your results.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
What Is the JAK2 Mutation Detection Panel (Exons 12‑15)?
This advanced genetic test uses Sanger sequencing to analyse exons 12–15 of the JAK2 gene, identifying mutations that drive Philadelphia‑negative myeloproliferative neoplasms (MPNs) such as polycythemia vera and essential thrombocythemia. يُعد هذا التحليل أداة أساسية في الإمارات لتأكيد التشخيص وتوجيه العلاج تحت إرشادات هيئة الصحة بدبي.
| Feature | Our Test (Sanger Sequencing) | Alternative (JAK2 V617F PCR Only) |
|---|---|---|
| Methodology | Gold‑standard Sanger Sequencing (exons 12–15) | Allele‑specific PCR (V617F only) |
| Detection Scope | All exon 12–15 mutations, including rarer variants | Only the JAK2 V617F mutation; misses exon‑12 abnormalities |
| Diagnostic Sensitivity | >99.9% for targeted region | ~97% for V617F, but false‑negative for other mutations |
| Turnaround Time | 7–8 working days | 3–5 working days |
Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY (DHA: 61713011), Consultant Molecular Pathologist, notes: “We appreciate that waiting for genetic test results can be stressful. This panel pinpoints the exact exon 12‑15 mutation to refine your personalised management plan, but results must always be interpreted alongside your full clinical picture. Your physician will guide you through every step.”
Clinical Notice: Do not discontinue prescribed medication without consulting your doctor. This test does not replace urgent clinical evaluation.
Safety Exclusion Criteria & ER Red Flags
- Do not proceed if you have active severe bleeding, a platelet count < 20,000/µL, or uncontrolled coagulopathy without prior medical clearance.
- Home collection is not performed on patients with unstable vital signs, altered mental status, or those unable to provide informed consent.
- Seek emergency care immediately if you experience sudden severe headache, vision changes, chest pain, leg swelling, or signs of blood clots such as deep vein thrombosis or pulmonary embolism.
- Bone marrow aspiration requires fasting and local anaesthetic administered by a physician – do not attempt to drive immediately afterwards.
Patient Frequently Asked Questions
Why is the JAK2 Exon 12‑15 panel preferred over a simple JAK2 V617F?
Snippet: This panel detects all mutations in exons 12–15, revealing rarer variants not found by V617F‑only tests. The JAK2 V617F mutation accounts for about 95% of PV cases, but up to 50% of essential thrombocythemia and primary myelofibrosis cases may harbour exon‑12 mutations that remain invisible to standard PCR. Our Sanger sequencing ensures no hidden abnormality is missed, providing the most complete genetic profile for diagnostic certainty and evidence‑based management.
يكشف هذا اللوح كل الطفرات في الإكسونات 12-15، بما في ذلك المتغيرات النادرة التي لا تلتقطها فحوصات جاك 2 V617F فقط. يضمن تسلسل سانجر لدينا عدم إغفال أي خلل جيني، مما يمنح الأطباء الصورة الأكمل لليقين التشخيصي.
How should I prepare for the blood or bone marrow collection?
Snippet: For blood, no special preparation is required; bone marrow needs doctor‑administered local anaesthesia and fasting. Peripheral blood collection is straightforward and can be performed during our home visit without any dietary restrictions. If a bone marrow sample is needed (for cases where peripheral blood is insufficient), your referring physician will coordinate the procedure; you’ll be asked to fast for at least 6 hours and a local anaesthetic will be used to minimise discomfort.
لا يحتاج سحب الدم إلى تحضيرات خاصة، بينما يتطلب سحب نخاع العظم صيامًا لمدة 6 ساعات وتخديرًا موضعيًا بإشراف الطبيب. سيقوم فريقنا بتنسيق الإجراء مع طبيبك.
Does insurance cover the JAK2 mutation panel in the UAE?
Snippet: Most UAE insurance plans cover this panel with a valid prescription; our team verifies billing directly via WhatsApp. Coverage depends on your policy and clinical indication. As soon as you share your Emirates ID and prescription, our insurance desk will perform a pre‑authorisation check and inform you of any out‑of‑pocket costs. We support all major local networks and can submit direct billing on your behalf.
تغطي معظم خطط التأمين في الإمارات هذا التحليل بوصفة طبية سارية، ويتولى فريقنا التحقق المباشر من التغطية عبر واتساب. راسلونا على +971 54 548 8731 مع وثيقتكم للبدء.
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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