Test Price
1,200 AED✅ Home Collection Available
JAK2 Mutation Detection Panel (Exon 12) in UAE | 1200 AED | DHA Licensed
Executive Summary & Core Metrics
Core Metrics
- Accuracy: 99.9% diagnostic sensitivity for exon 12 variants via Sanger sequencing.
- Turnaround Time: 7–8 business days from receipt of sample.
- Price: 1200 AED (all inclusive).
- Collection: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Telephonic post-test interpretation by a Consultant Medical Geneticist.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The JAK2 Mutation Detection Panel (Exon 12) employs Sanger sequencing—the gold standard—to identify rare pathogenic variants in the JAK2 gene. This test is critical for diagnosing myeloproliferative neoplasms (MPNs) such as polycythemia vera and essential thrombocythemia, especially when common JAK2 V617F mutations are absent.
| Feature | This Panel (DNA Labs UAE) | Standard Alternative |
|---|---|---|
| Methodology | Sanger Sequencing (Gold Standard) | PCR-based Screening |
| Sensitivity | 99.9% for rare exon 12 mutations | Limited to common JAK2 V617F; may miss exon 12 variants |
| Turnaround Time | 7–8 Days | 5–7 Days |
| Cost | 1200 AED | ~900 AED (incomplete coverage) |
| Accreditation | ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | Varies |
Physician Insight & Safety Protocols
“As a Consultant Medical Geneticist, I emphasize that this exon 12 panel refines the diagnosis of myeloproliferative neoplasms when standard V617F testing is negative. Results must be interpreted alongside full blood counts and clinical history. Genetic counseling is recommended for all patients. Do not alter any prescribed therapy without your hematologist’s guidance.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA ID: 9294403
Advisory: Medication & Test Guidance
⚠️ Important:
Never discontinue prescribed medications without consulting your treating physician. Test results are not a substitute for professional medical evaluation. If you experience sudden severe headache, vision changes, chest pain, or uncontrolled bleeding, seek emergency care immediately.
Exclusion Criteria & Emergency Red Flags
- Not for individuals under 18 without a legal guardian’s consent and a valid prescription.
- Not applicable for pre-surgery clearance, pregnancy, or international travel without a doctor’s prescription as per UAE regulations.
- Bone marrow aspiration is an invasive procedure; proceed only if clinically indicated by a hematologist.
- If you experience any red-flag symptoms (e.g., chest pain, sudden vision loss, severe headache, uncontrolled bleeding), seek emergency care and inform the laboratory.
Patient FAQ & Clinical Guidance
1. What is the purpose of the JAK2 exon 12 mutation test?
The test identifies rare genetic variants in the JAK2 gene (exon 12) that are associated with myeloproliferative neoplasms such as polycythemia vera and primary myelofibrosis. It is specifically used when the common JAK2 V617F mutation is absent, providing a definitive diagnosis and guiding targeted therapy.
2. How long does it take to get results?
Results are available within 7 to 8 business days from sample receipt. A digital report is issued along with a telephonic consultation from our Consultant Medical Geneticist to discuss findings and next steps.
3. Is any special preparation required before the test?
No fasting is needed. However, the sample (peripheral blood or bone marrow aspirate) must be collected at an accredited hospital under strict clinical conditions. A doctor’s prescription is mandatory. Inform the healthcare provider if you are on anticoagulant therapy.
4. Can the test be done at home?
No. Because the sample may require bone marrow aspiration, which is an invasive procedure, collection is restricted to hospital settings only. Mobile phlebotomy is not available for this test to ensure patient safety and sample integrity.
UAE Regulatory & Data Privacy Adherence
Data Protection & Clinical Compliance
Your health data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring patient safety and informed consent.
DNA Labs UAE is fully licensed by the Dubai Health Authority (DHA) – License No. 1143 – and operates under ISO 9001:2015 quality management standards.
Clinical & Logistical Metadata
| Test Name | JAK2 Mutation Detection Panel (Exon 12) |
| Price (AED) | 1200 |
| Turnaround Time | 7–8 Business Days |
| Sample Type / Matrix | Peripheral Blood or Bone Marrow Aspirate |
| Methodology Used | Sanger Sequencing (Gold Standard) |
| ICD-10-CM Code | D45 (Polycythemia vera) |
| LOINC Code | 78299-7 (JAK2 gene mutation analysis in Blood or Bone Marrow by Sequencing) |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians