Test Price
2,800 AED✅ Home Collection Available
PIK3CD Gene Immunodeficiency Type 14 Genetic Test in UAE | AED 2800
Executive Summary & Core Metrics
Key Metrics
This NGS test provides molecular diagnosis of Activated PI3K Delta Syndrome (APDS) with >99.9% sensitivity, using ISO 9001:2015 certified SeqStudio platform and Sanger confirmation.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified SeqStudio NGS Platform, with dual Sanger confirmation.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Immediate post-analytical telephonic consultation with a Consultant Clinical Geneticist for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731; major UAE networks accepted.
Test Overview & Methodology
The PIK3CD gene test screens for pathogenic variants causing Activated PI3K Delta Syndrome (APDS), a primary immunodeficiency with lymphoproliferation and lymphoma risk. This NGS full-gene sequencing includes copy number variant detection and is confirmed by Sanger sequencing for clinically actionable variants.
| Feature | Our Test (PIK3CD NGS) | Closest Alternative (Whole Exome) |
|---|---|---|
| Methodology | NGS full-gene sequencing + copy number variant detection | Exome-wide with incidental findings; may miss deep intronic variants |
| Diagnostic Yield | >99% for known coding mutations; proven sensitivity | ~60-70% for targeted gene; requires orthogonal confirmation |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Cost (AED) | 2,800 | 5,000+ |
| Clinical Validation | ISO 9001:2015; LOINC 96090-9 | Varies by provider |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA: 9294403)
A positive PIK3CD variant is diagnostic for APDS, yet negative sequencing does not exclude the condition due to deep intronic mutations or alternative genetic causes. Timely molecular diagnosis allows initiation of targeted PI3Kδ inhibitors and reduces morbidity from recurrent infections and lymphoma risk. All results should be integrated with immunological phenotyping for comprehensive management.
Medication Advisory
Do not discontinue prescribed immunosuppressants, antibiotics, or immunoglobulin replacement without consulting your specialist. This test informs treatment decisions; it does not replace ongoing clinical monitoring.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Inability to provide adequate DNA sample (severe leukopenia); active severe infection requiring hospitalization; minors without legal guardian consent per UAE Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Emergency Signs: Rapidly enlarging lymph nodes, unexplained fever >39°C, respiratory distress, or signs of sepsis — seek immediate ER care. This test is not an emergency diagnostic tool.
Patient FAQ & Clinical Guidance
1. What is the PIK3CD gene test used for?
This NGS test detects pathogenic variants in the PIK3CD gene causing Activated PI3K Delta Syndrome, a primary immunodeficiency with recurrent infections and lymphoma predisposition. It confirms the molecular diagnosis when clinical and immunological findings suggest APDS, enabling targeted therapy and family screening.
2. How is the sample collected for this test?
A home collection of blood, buccal swab, or dried blood spot on FTA card is performed by a DHA-registered phlebotomist under cold-chain protocol. The procedure is quick, minimally invasive, and available across all UAE Emirates from 8 AM to 11 PM daily.
3. How long until I receive my PIK3CD DNA test results?
Your comprehensive DNA sequencing report is delivered within 3 to 4 weeks, inclusive of Sanger confirmation and clinical interpretation. A post-genetic counselling session is scheduled immediately upon report release to discuss findings and next steps.
UAE Regulatory & Data Privacy Adherence
This laboratory strictly adheres to the Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is securely encrypted, access-controlled, and handled in full compliance with UAE data protection standards. ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | PIK3CD Gene Sequencing (APDS Type 14) |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood, Buccal Swab, or Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) full-gene sequencing with Sanger confirmation and copy number variant detection |
| ICD-10-CM Code | D81.8, C83.90, Z15.09 |
| LOINC Code | 96090-9 |
| DHA Facility License & Laboratory Address Invariants | DHA Facility License: 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians