Test Price
2,800 AED✅ Home Collection Available
DCLRE1C Gene Omenn Syndrome Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين DCLRE1C لمتلازمة أومين في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: دقة تشخيصية بنسبة 99.9% عبر مختبر معتمد وفق معايير الأيزو، مع خدمة سحب منزلي فاخرة واستشارة سريرية بعد الفحص.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain and VIP Mobile Phlebotomy — 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation, ensuring every patient understands next steps.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
- This service complies with Federal Decree-Law No. 41 of 2024 (Art. 87), CDS Law 2026 for minors, and UAE PDPL data privacy law. Facility License: 9834453.
Comprehensive Genetic Insight into Omenn Syndrome
The DCLRE1C gene encodes a protein critical for V(D)J recombination and immune cell development. This NGS test detects pathogenic variants causing Omenn syndrome, a severe combined immunodeficiency presenting in infancy. Early molecular diagnosis enables gene-matched therapy and family planning. (يكشف هذا الاختبار الجيني عن طفرات جين DCLRE1C المسؤولة عن متلازمة أومين النادرة)
| Feature | Our Test (DNA Labs UAE) | Standard Hospital Panel |
|---|---|---|
| Precision / Method | NGS (Next Generation Sequencing) with full gene coverage, ISO 9001:2015 | Sanger sequencing or targeted mutation panels; limited resolution |
| Turnaround Time | 3 to 4 Weeks | 6–8 Weeks |
| Clinical Sensitivity | 99.9% for single-nucleotide variants, indels, and splice-site mutations | Variable, often lower due to incomplete gene coverage |
| Sample Type | Whole Blood, Extracted DNA, or One-drop Blood on FTA Card | Typically only whole blood |
Clinical Insights & Safety Protocol – Dr. PRABHAKAR REDDY (DHA: 61713011)
“I strongly advise that every genetic test result be correlated with the patient’s complete clinical picture. A negative result does not exclude a diagnosis, and a positive result should be interpreted by a clinical geneticist or immunologist before any treatment decisions are made. Your child’s care depends on a multidisciplinary approach.”
Medication Warning:
Do not discontinue any prescribed medication or initiate new therapy without consulting your treating physician. Genetic results must be integrated into the overall management plan.
Exclusion Criteria & Emergency Red Flags:
- Acute febrile illness or systemic infection requiring immediate medical attention – reschedule after recovery.
- Recent blood transfusion within 2 weeks may interfere with DNA extraction from whole blood (FTA card acceptable).
- Seek urgent care if the child develops severe rash, respiratory distress, or failure to thrive while awaiting results – these may indicate Omenn syndrome progression.
- This test is not intended for prenatal diagnosis; consult a genetic counselor for reproductive options.
Frequently Asked Clinical Questions (FAQ)
Q1: What exactly does the DCLRE1C gene test detect and why is it important?
Snippet Answer: The test identifies mutations in the DCLRE1C gene that cause Omenn syndrome, a life-threatening primary immunodeficiency, enabling precise diagnosis and curative treatment planning.
This NGS assay analyzes all coding exons and splice junctions of the DCLRE1C gene using DNA extracted from a simple blood sample. Results guide whether a patient is eligible for hematopoietic stem cell transplantation or gene therapy. (يكشف الاختبار عن الطفرات المسببة لمتلازمة أومين، مما يساعد في التخطيط للعلاج المناعي وزراعة الخلايا الجذعية)
Q2: How should I prepare my child for the sample collection, and is a fasting state required?
Snippet Answer: No fasting is required; the main preparation involves arranging a genetic counselling session to draw a family pedigree chart and discuss clinical history.
Our phlebotomist will collect either a blood sample, an FTA card spot, or extracted DNA according to the chosen service. The clinical history form should list all affected family members and any previous immunological workup. Home collection is available in all UAE emirates between 8 AM and 11 PM.
Q3: What is the turnaround time and how will I receive the results?
Snippet Answer: Results are delivered via a secure encrypted portal within 3 to 4 weeks, accompanied by a comprehensive clinical interpretation and telephonic guidance from our genetic counsellors.
You will receive a detailed PDF report including the identified variants, their zygosity, and clinical significance as per ACMG guidelines. Our team then schedules a post- consultation to explain the findings and recommend further immunological evaluations if needed.
DNA Labs UAE is a DHA-licensed facility (License No. 9834453) and adheres to ISO 9001:2015 quality standards (Cert: INT/EGQ/2509DA/3139). All testing complies with UAE Federal Decree-Law No. 41 of 2024 (Art. 87) and the PDPL. For minor patients, consent is obtained per CDS Law 2026. Contact for support: WhatsApp +971 54 548 8731.
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التحقق من التغطية التأمينية
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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