Test Price
2,800 AED✅ Home Collection Available
LCK Gene (Immunodeficiency Type 22) Genetic Test in UAE | 2,800 AED | DHA Licensed
Executive Summary & Core Metrics
The LCK Gene (Immunodeficiency Type 22) Genetic Test is a precision molecular assay utilizing targeted next-generation sequencing (NGS) to detect pathogenic variants in the LCK gene, which causes severe combined immunodeficiency (SCID) type 22. This test enables early diagnosis, informed family counselling, and tailored clinical management under DHA-recognised standards.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This targeted NGS assay performs deep sequencing of the LCK gene coding region to identify deletions, point mutations, and structural variants that impair T-cell development and function. Results are correlated with clinical presentation and family history to guide paediatric immunology management.
| Feature | Our Test – LCK NGS | Closest Alternative (Whole Exome Sequencing) |
|---|---|---|
| Precision (Sensitivity) | 99.9% for LCK gene mutations | ~98% for exome-wide variants; incidental findings possible |
| Methodology | Targeted NGS with deep coverage of LCK | Broad exome capture + NGS |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Clinical Focus | Direct diagnosis of LCK-deficient SCID | Broad genetic screening; often requires secondary reanalysis |
Physician Insight & Safety Protocols
“In my practice, I have seen how a precise genetic diagnosis transforms the management of severe early-onset immunodeficiency. The LCK gene test offers a definitive answer for families navigating recurrent infections and eczematous presentations. However, NGS findings must be integrated with immunological phenotyping and a three-generation pedigree before concluding. Always partner with a paediatric immunologist for comprehensive care.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Medication Advisory
Do not discontinue prescribed immunoglobulin therapy or immunosuppressive medications without consulting your physician. Abrupt cessation can precipitate severe infections and clinical deterioration. Always discuss any concerns about medication side effects with your treating specialist before making changes.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Active untreated severe infection, haemodynamic instability, or recent vaccination within 14 days (consult physician before scheduling).
- ER Red Flags: High fever exceeding 38.5°C, respiratory distress, cyanosis, altered consciousness, or new petechial rash after sample collection — seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What is the LCK Gene Immunodeficiency Type 22 Genetic Test?
This test uses targeted next-generation sequencing to detect mutations in the LCK gene that cause severe combined immunodeficiency (SCID) type 22. It analyses the entire coding region to identify deletions, point mutations, and structural variants impairing T-cell development and function, enabling early diagnosis and personalised treatment planning.
2. How is the sample collected and what is the turnaround time?
A certified phlebotomist collects whole blood, extracted DNA, or a dried blood spot via VIP Mobile Phlebotomy at your home between 8 AM and 11 PM. Samples are transported in validated temperature-controlled cold-chain containers to our ISO-accredited laboratory. Results are delivered within 3–4 weeks.
3. Does insurance cover this test in the UAE?
Many UAE insurance plans cover genetic testing for immunodeficiency when medically necessary. Our team verifies direct billing coverage via WhatsApp at +971 54 548 8731. Send your insurance card copy for confirmation before scheduling. Out-of-pocket cost is 2,800 AED if not covered.
4. What preparation is required before the test?
No fasting or medication avoidance is required unless instructed by your physician. Please provide a detailed clinical history including a family pedigree for LCK-related immunodeficiency. A genetic counselling session is recommended before sample collection to ensure informed consent.
UAE Regulatory & Data Privacy Adherence
Your Data. Protected by Law.
DNA Labs UAE complies fully with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access-restricted, and processed solely for diagnostic purposes. Clinical safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability.
DHA Facility License No. 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE
Clinical & Logistical Metadata
| Test Name | LCK Gene (Immunodeficiency Type 22) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or Dried Blood Spot |
| Methodology Used | Targeted NGS (Next Generation Sequencing) with Deep Coverage |
| ICD-10-CM Code | D81.0 |
| LOINC Code | 21659-5 |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians