Test Price
2,800 AED✅ Home Collection Available
NECAP1 Gene Early Infantile Epileptic Encephalopathy Type 21 Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
Clinical Excellence & UAE Compliance: Our ISO 9001:2015 certified laboratory delivers 99.9% diagnostic sensitivity for NECAP1 variant detection via advanced NGS, ensuring accurate identification of pathogenic mutations linked to EIEE21.
Premium Home Collection: VIP mobile phlebotomy service across all Emirates (8 AM–11 PM) with ISO-certified cold-chain transport, preserving DNA integrity from collection to sequencing.
Post-Test Guidance: Complimentary telephonic genetic counseling session to interpret results and discuss next steps, aligned with Federal Decree-Law No. 4 of 2016 on Medical Liability and the UAE Personal Data Protection Law (PDPL) for minor data protection.
Insurance Made Easy: Direct billing verification via WhatsApp at +971 54 548 8731—we confirm coverage before the draw.
Test Overview & Methodology
The NECAP1 Gene NGS Test sequences the entire coding region of NECAP1 to diagnose early infantile epileptic encephalopathy type 21 (EIEE21), an autosomal recessive disorder causing severe infantile-onset seizures and developmental regression. Our accredited assay achieves >99.9% analytical sensitivity and specificity, exceeding standard single-gene tests by covering all coding exons with a turnaround time of just 3–4 weeks.
| Feature | Our NECAP1 NGS Test | General Multi-Gene Panel |
|---|---|---|
| Methodology | Next-Generation Sequencing (NGS) with full exon coverage | May use limited Sanger sequencing or targeted gene subsets |
| Turnaround Time | 3–4 Weeks (urgent options available) | 4–8 Weeks |
| Variant Detection | Full gene analysis including deep intronic regions | Often limited to hotspot exons |
| Clinical Support | Post-test genetic counseling included | Rarely included |
Physician Insight & Safety Protocols
"Genetic testing for NECAP1 provides a definitive diagnosis for EIEE21, which is crucial for guiding treatment and family counseling. However, it is essential to interpret results within the full clinical picture and EEG findings. A negative result does not exclude other genetic or non-genetic causes. Always collaborate with a pediatric neurologist for comprehensive management."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Medication Continuity
⚠️ Do not discontinue any antiepileptic medication without consulting your treating physician. Genetic testing complements, not replaces, ongoing clinical management.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Individuals with acute febrile illness or hemodynamic instability; specimens from patients on high-dose anticoagulants require physician clearance.
- Exclusion: Refusal or inability of parent/guardian to provide informed consent for a minor.
- Emergency Red Flags: New-onset prolonged seizure (>5 minutes), status epilepticus, or sudden deterioration in consciousness — seek emergency care immediately, not a scheduled lab test.
- If a sibling shows similar symptoms, consult a clinical geneticist urgently before sample collection.
Patient FAQ & Clinical Guidance
1. What is the NECAP1 gene and why is this test needed?
The NECAP1 gene encodes a protein essential for neuronal vesicle recycling; pathogenic mutations cause early infantile epileptic encephalopathy type 21, characterized by refractory seizures and neurodevelopmental stagnation. This test identifies disease-causing variants to guide precise treatment, inform family planning, and connect you with ongoing research studies.
2. How is the sample collected, and is it painful for my infant?
Our pediatric-trained phlebotomists use a gentle heel-stick or venous draw with a topical anesthetic; a single drop on an FTA card is sufficient. The procedure is swift and comparable to a routine vaccination.
3. Will my health insurance cover the 2800 AED cost?
Most UAE comprehensive health plans include genetic testing for medically indicated neurological conditions. Simply send your insurance card via WhatsApp to +971 54 548 8731, and we will confirm pre-authorization within 1 hour — with no upfront payment if approved.
UAE Regulatory & Data Privacy Adherence
At DNA Labs UAE, we strictly adhere to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields to protect your genetic data. Our genetic counseling and consent processes comply with Federal Decree-Law No. 4 of 2016 on Medical Liability. Your data is encrypted and used solely for diagnostic purposes.
Clinical & Logistical Metadata
| Test Name | NECAP1 Gene Sequencing (EIEE21) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Blood or Heel-stick (Infants) – VIP home phlebotomy available |
| Methodology Used | Next-Generation Sequencing (NGS) – Full Gene Coverage |
| ICD-10-CM Code | G40.4 (Other generalized epilepsy and epileptic syndromes) |
| LOINC Code | 83464-2 (Gene mutation detection in Blood or Tissue by Molecular genetics method) |
| DHA Facility License & Laboratory Address | DHA License: 1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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