CUL3 Gene Pseudohypoaldosteronism type 2E Genetic Test
Are you or your loved ones experiencing symptoms such as dehydration, low blood pressure, and electrolyte imbalance? It could be pseudohypoaldosteronism type 2E (PHA2E), a rare genetic disorder caused by mutations in the CUL3 gene. At DNA Labs UAE, we offer a comprehensive genetic test to diagnose PHA2E and provide valuable information for its management and treatment.
Test Name: CUL3 Gene Pseudohypoaldosteronism type 2E Genetic Test
- Components: CUL3 gene
- Price: 4400.0 AED
- Sample Condition: Blood or Extracted DNA or One drop Blood on FTA Card
- Report Delivery: 3 to 4 Weeks
- Method: NGS Technology
- Test type: Vascular Diseases
- Doctor: General Physician
- Test Department: Genetics
Pre Test Information
Prior to undergoing the CUL3 Gene Pseudohypoaldosteronism type 2E Genetic Test, it is important to provide the clinical history of the patient. Additionally, a genetic counseling session will be conducted to draw a pedigree chart of family members affected by the CUL3 gene mutation.
Test Details
The CUL3 gene, also known as cullin 3, plays a crucial role in regulating various cellular processes. However, mutations in this gene have been associated with pseudohypoaldosteronism type 2E (PHA2E), a rare genetic disorder characterized by an electrolyte imbalance, particularly sodium and potassium. Symptoms of PHA2E include dehydration, low blood pressure, and increased levels of aldosterone.
To diagnose PHA2E caused by CUL3 gene mutations, we utilize Next-Generation Sequencing (NGS) technology. This method allows us to analyze the DNA sequence of an individual and identify genetic variations or mutations associated with certain diseases or conditions, including PHA2E. To perform the test, a sample of DNA is collected, usually through a blood sample or a cheek swab. The DNA is then sequenced using NGS technology, enabling the detection of any variations or mutations in the CUL3 gene.
It is important to note that genetic testing for CUL3 gene mutations is typically recommended for individuals who exhibit symptoms consistent with PHA2E or have a family history of the condition. The test should be performed and interpreted by a qualified healthcare professional or genetic counselor, who can provide appropriate guidance and support.
At DNA Labs UAE, we are committed to providing accurate and reliable genetic testing services. Our CUL3 Gene Pseudohypoaldosteronism type 2E Genetic Test can help diagnose PHA2E and assist in the management and treatment of this rare genetic disorder. Contact us today to schedule an appointment or learn more about our services.
| Test Name | CUL3 Gene Pseudohypoaldosteronism type 2E Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Vascular Diseases |
| Doctor | General Physician |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for CUL3 Gene Pseudohypoaldosteronism type 2E NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CUL3 Gene Pseudohypoaldosteronism type 2E NGS Genetic DNA Test gene CUL3 |
| Test Details | CUL3 gene, also known as cullin 3, is a gene that provides instructions for making a protein involved in the regulation of various cellular processes. Mutations in the CUL3 gene have been associated with a rare genetic disorder called pseudohypoaldosteronism type 2E (PHA2E). Pseudohypoaldosteronism type 2E is a condition characterized by an imbalance of electrolytes in the body, particularly sodium and potassium. This imbalance can lead to symptoms such as dehydration, low blood pressure, and increased levels of aldosterone (a hormone involved in regulating sodium and potassium levels). NGS (Next-Generation Sequencing) genetic testing is a method used to analyze the DNA sequence of an individual. It allows for the identification of genetic variations or mutations that may be associated with certain diseases or conditions, including PHA2E caused by mutations in the CUL3 gene. The NGS genetic test for CUL3 gene mutations involves collecting a sample of DNA, usually through a blood sample or a cheek swab. The DNA is then sequenced using NGS technology, which allows for the detection of any variations or mutations in the CUL3 gene. The results of the test can help diagnose pseudohypoaldosteronism type 2E and provide valuable information for the management and treatment of the condition. It is important to note that genetic testing for CUL3 gene mutations is typically recommended for individuals who have symptoms consistent with pseudohypoaldosteronism type 2E or a family history of the condition. Genetic testing should be performed and interpreted by a qualified healthcare professional or genetic counselor who can provide appropriate guidance and support. |
