Test Price
1,800 AED✅ Home Collection Available
WT-1 Mutation Detection Test in UAE | 1800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO accredited processing.
- Premium Logistics: Hospital extraction only – sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Telephonic post-test clinical guidance in result interpretation.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The WT-1 Mutation Detection Test identifies pathogenic variants in the Wilms tumor 1 (WT1) gene through high-sensitivity PCR sequencing (Sanger method), aiding in diagnosis, prognosis, and monitoring of Wilms tumor, Denys–Drash syndrome, and Frasier syndrome. This DNA Labs UAE test delivers results in 18 working days from a blood or bone marrow sample collected under strict clinical conditions. A duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory. Sample accepted daily by 11 am; sample must be kept refrigerated – never frozen. ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139).
| Feature | Our WT-1 Mutation Detection Test | Standard NGS Panel |
|---|---|---|
| Method | PCR Sequencing (Sanger) – gold-standard single-gene analysis | Next-Generation Sequencing – broader but may miss specific WT1 variants |
| Diagnostic Precision | 99.9% analytical sensitivity for targeted WT1 mutations | Variable; lower coverage in WT1 region |
| Turnaround Time | 18 working days | 20–30 days typical |
| Regulatory & Quality | DHA/MOHAP compliant, ISO 9001:2015, facility license 1143 | Variable accreditations |
Physician Insight & Safety Protocols
“Understanding the genetic basis of a condition can be life-changing. The WT-1 mutation test provides precise molecular information that guides treatment decisions for Wilms tumor and related syndromes. However, always interpret results within the full clinical context and in consultation with a multidisciplinary team.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)
Advisory: Medication Continuity & Clinical Oversight
Do not discontinue or alter any prescribed medication without consulting your treating physician. This test is a diagnostic aid and does not replace regular medical follow-up. If you experience new or worsening symptoms such as unexplained pain, fever, or changes in urinary habits, seek immediate medical evaluation.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Sample not collected in lavender-top EDTA tube; sample frozen instead of refrigerated; missing or inadequately filled Genomics Clinical Information Requisition Form (Form 20).
- Emergency Red Flags: Sudden severe bone pain, frank hematuria, rapidly enlarging abdominal mass, unexplained high fever – proceed to nearest emergency department immediately.
Patient FAQ & Clinical Guidance
1. What is the purpose of a WT-1 mutation test?
The WT-1 mutation test identifies specific gene changes needed for diagnosing Wilms tumor and associated syndromes. It differentiates sporadic Wilms tumor from genetic syndromes like Denys–Drash and Frasier syndrome, enabling precise risk stratification and personalised surveillance plans for affected children and young adults.
2. How should I prepare for the blood or bone marrow collection?
No fasting is required; simply ensure your requisition form is fully completed. A trained clinician will collect 4 mL of blood or a bone marrow aspirate using a lavender-top EDTA tube. The sample must be kept refrigerated – never frozen – to preserve DNA integrity until testing begins. Collection occurs within an accredited hospital facility.
3. What does a positive WT-1 mutation result mean for my child?
A positive result confirms a pathogenic WT1 gene mutation, strongly supporting a diagnosis of Wilms tumor or a predisposing syndrome. This finding guides your specialist to recommend targeted therapies, nephron-sparing surgery where possible, and screening for associated anomalies such as genitourinary malformations or renal failure risk.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Legal Compliance
This service strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is handled with the highest confidentiality under DHA/MOHAP guidelines. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | WT-1 Mutation Detection Test |
| Price (AED) | 1800 |
| Turnaround Time | 18 working days |
| Sample Type / Matrix | Blood or bone marrow – Hospital extraction only; sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety. |
| Methodology Used | PCR Sequencing (Sanger) |
| ICD-10-CM Code | C64, Z15.07 |
| LOINC Code | 92918-3 |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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