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Test Price

1,800 AED

✅ Home Collection Available

WT-1 Mutation Detection Test in UAE | 1800 AED | 2026 DHA Guidelines

تحليل الكشف عن طفرة WT-1 في الإمارات | 1800 درهم | معتمد من هيئة الصحة بدبي

Executive Summary (الملخص التنفيذي)

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
  • Premium Logistics: Paid Hospital‑Grade Home Collection via ISO Certified Cold‑Chain Home Collection & VIP Mobile Phlebotomy.
  • Clinical Guidance: Telephonic Post‑Test Clinical Guidance in result interpretation.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

الملخص التنفيذي: تحليل دقيق بطريقة التسلسل الجيني للكشف عن طفرة WT-1، معتمد من هيئة الصحة بدبي وموثق وفقاً لمعايير ISO 9001:2015، لضمان أعلى درجات الحساسية التشخيصية تصل إلى 99.9%، ويشمل خدمة سحب منزلي مع نقل مبرد، واستشارة سريرية هاتفية بعد النتيجة.

Overview

WT-1 Mutation Detection Test identifies pathogenic variants in the Wilms tumor 1 (WT1) gene through high‑sensitivity PCR sequencing, aiding in diagnosis, prognosis, and monitoring of Wilms tumor, Denys‑Drash syndrome, and Frasier syndrome. This Dubai Central Laboratory test delivers results in 18 days with a 2 mL EDTA blood or bone marrow sample via ISO‑certified cold‑chain logistics.

Feature Our WT-1 Mutation Detection Test Standard NGS Panel
Method PCR Sequencing (Sanger) – gold‑standard single‑gene analysis Next‑Generation Sequencing – broader but may miss specific WT1 variants
Diagnostic Precision 99.9% analytical sensitivity for targeted WT1 mutations Variable; lower coverage in WT1 region
Turnaround Time 18 working days 20–30 days typical
Regulatory & Quality DHA/MOHAP compliant, ISO 9001:2015, facility license 9834453 Variable accreditations

Physician Insight & Safety Protocol

“I understand how concerning it can be waiting for genetic results; this WT‑1 test is a critical tool, but always interpret it in the context of your complete clinical picture. Please remember that no single test can replace a thorough specialist evaluation. If you experience any sudden pain, swelling, or blood in urine, seek immediate medical attention.”

— Dr. PRABHAKAR REDDY, Specialist (DHA License: 61713011)

⚠ Medication Warning: Do not discontinue prescribed medication without consulting your doctor.

Exclusion Criteria & Emergency Red Flags

  • Exclusion: Sample not collected in Lavender top EDTA tube; sample frozen instead of refrigerated; missing or inadequately filled Genomics Clinical Information Requisition Form (Form 20).
  • Emergency Red Flags: Sudden severe bone pain, frank hematuria, rapidly enlarging abdominal mass, unexplained high fever—proceed to nearest emergency department immediately.

Pre‑test Requirement: Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory. Sample: 4 mL (2 mL min.) whole blood / bone marrow in 1 Lavender top (EDTA) tube, shipped refrigerated. DO NOT FREEZE. Sample accepted daily by 11 am; report in 18 days.

Patient FAQ & Clinical Guidance

1. What is the purpose of a WT-1 mutation test?

The WT-1 mutation identifies specific gene changes needed for diagnosing Wilms tumor and syndromes. It differentiates sporadic Wilms tumor from genetic syndromes like Denys‑Drash and Frasier syndrome, enabling precise risk stratification and personalised surveillance plans for affected children and young adults.

يحدد اختبار طفرة WT-1 التغيرات الجينية المحددة اللازمة لتشخيص ورم ويلمز والمتلازمات المرتبطة به، مما يساعد في التمييز بين الحالات المتفرقة والمتلازمات الوراثية لوضع خطط متابعة شخصية.

2. How should I prepare for the blood or bone marrow collection?

No fasting is required; simply ensure your requisition form is fully completed. A trained phlebotomist will collect 4 mL of blood or a bone marrow aspirate using a lavender‑top EDTA tube, and the sample must be kept refrigerated—never frozen—to preserve DNA integrity until testing begins.

لا داعي للصيام؛ فقط تأكد من استكمال نموذج الطلب بالكامل، وسيقوم أخصائي بسحب 4 مل من الدم أو نخاع العظم في أنبوب EDTA بنفسجي، مع حفظ العينة مبردة وعدم تجميدها أبداً.

3. What does a positive WT-1 mutation result mean for my child?

A positive result confirms a pathogenic WT1 gene mutation, strongly supporting a diagnosis of Wilms tumor or a predisposing syndrome. This finding guides your specialist to recommend targeted therapies, nephron‑sparing surgery where possible, and screening for associated anomalies such as genitourinary malformations or renal failure risk.

تؤكد النتيجة الإيجابية وجود طفرة ممرضة في جين WT1، مما يدعم تشخيص ورم ويلمز أو متلازمة وراثية، ويوجه الطبيب نحو علاجات موجهة وجراحة محافظة على الكلية وفحص للتشوهات المصاحبة.

UAE Regulatory Compliance

This service strictly adheres to Federal Decree‑Law No. 41 of 2024 (Art. 87) on health services, the 2026 Child Safety (CDS) Law for minors, and the UAE Personal Data Protection Law (PDPL). All genetic data is handled with the highest confidentiality under DHA/MOHAP guidelines.

ISO 9001:2015 Certified | Cert: INT/EGQ/2509DA/3139 Facility License: 9834453 DHA/MOHAP Approved

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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.

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All reports reviewed by DHA-Certified physicians