Test Price
1,200 AED✅ Home Collection Available
MET Gene Amplification (FISH) Test in UAE – DNA Labs UAE
Executive Summary & Core Metrics
🏅 99.9% Diagnostic Sensitivity – ISO‑Certified Processing
Premium Logistics: Secure Medical Courier Solid Tissue Specimen Retrieval – Your existing FFPE tumor block or biopsy slides are collected directly from your treating hospital's pathology department under a certified cold chain.
Clinical Guidance: Post‑test telephonic consultation with a board‑reviewed specialist to interpret MET amplification results and discuss targeted therapeutic implications.
Insurance: Direct Billing Verification available. WhatsApp: +971 54 548 8731.
Test Overview & Methodology
The MET (mesenchymal‑epithelial transition) proto‑oncogene amplification test detects copy‑number gains of the MET gene (7q31) in tumor tissue via Fluorescence In Situ Hybridization (FISH). Identifying amplification helps oncologists select targeted therapies—such as MET inhibitors—in non‑small cell lung cancer and other solid tumors. This single‑gene, tissue‑based DNA copy‑number analysis provides cellular context for precise therapeutic decision‑making.
| Feature | Our Test: MET FISH | NGS Panel (Liquid Biopsy) |
|---|---|---|
| Precision | Single‑gene, tissue‑based DNA copy‑number analysis with cellular context (FISH) | Broader panel; may miss low‑level amplification or require sequencing depth |
| Turnaround | 4 working days | 7–14 days typically |
| Clinical Actionability | Direct guidance for MET TKI therapy (e.g., capmatinib, tepotinib) | Requires bioinformatics filtering; may need orthogonal confirmation |
Physician Insight & Safety Protocols
"MET amplification on FISH provides a direct, quantifiable measure of gene copy number in situ, offering high specificity for identifying patients who may derive substantial benefit from MET tyrosine kinase inhibitors. It serves as a critical orthogonal validation for NGS-detected amplifications. However, results must be contextualized within the broader histopathologic and clinical landscape."
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology, DHA Registration ID: 61713011
Clinical Advisory & Medication Safety
⚠️ Medication Advisory
Do not discontinue or alter any prescribed oncology medication based solely on this test result. Always consult your treating oncologist for therapeutic adjustments.
Patient Safety: Exclusion Criteria & Emergency Red Flags
- Insufficient tumor content (<10%) in FFPE block – test cannot be performed.
- Specimen processed with non‑formalin‑based fixatives (e.g., Bouin’s solution) – FISH signal may be compromised.
- No completed Form 17 (Chromosome & FISH Analysis Requisition) – sample will be rejected.
- ER Red Flag: If you are experiencing new‑onset severe symptoms (uncontrolled pain, breathing difficulty, neurological changes), seek immediate emergency care; do not delay for test results.
Patient FAQ & Clinical Guidance
1. What does MET amplification mean for my cancer treatment?
MET amplification indicates the tumor possesses extra copies of the MET gene, making it an actionable target for precision therapies like capmatinib or tepotinib. A positive FISH result is a strong biomarker for selecting patients who may respond favorably to MET inhibitors. Your oncologist will integrate this result with other molecular and clinical findings to determine the optimal treatment pathway.
2. How is my tissue sample collected for this test?
No new biopsy or phlebotomy is required. Our Secure Medical Courier Solid Tissue Specimen Retrieval service collects your existing FFPE tumor block or biopsy slides directly from the pathology department of your treating hospital. Our team manages the cold-chain transport and all regulatory paperwork, including Form 17.
3. When will I receive my MET FISH report?
The MET FISH report is finalized within 4 working days from sample receipt. The report is securely transmitted to your requesting oncologist via DHA-compliant digital channels. A dedicated clinical specialist from DNA Labs UAE will provide a post-result telephonic consultation to explain the implications of the findings.
UAE Regulatory & Data Privacy Adherence
Trust & Compliance Framework
DNA Labs UAE strictly adheres to the UAE’s highest standards for genetic data handling and patient privacy:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL): Governs the collection, processing, and storage of your personal and genetic data. Your data is encrypted and never shared without explicit consent.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields: Ensures all health information and communication technology systems meet stringent security and interoperability standards for clinical data exchange.
- Federal Decree-Law No. 4 of 2016 on Medical Liability: Upholds your rights regarding informed consent and clinical safety throughout the diagnostic pathway.
Laboratory License: DHA Facility License No. 1143. Certified under ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | MET Gene Amplification (FISH) |
| Price (AED) | 1,200 AED |
| Turnaround Time | 4 Working Days |
| Sample Type / Matrix | Tumor Tissue (FFPE Block / Biopsy Slides) |
| Methodology Used | Fluorescence In Situ Hybridization (FISH) – Dual-Color Probe |
| ICD-10-CM Code | C80.1 (Malignant Neoplasm) – Dependent on primary indication |
| LOINC Code | 48647-3 (MET gene copy number) |
| DHA License & Address | DHA Facility License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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