Test Price
2,800 AED✅ Home Collection Available
SUFU Gene Basal Cell Nevus Syndrome Genetic Test in UAE | 2,800 AED | 2026 DHA Guidelines
تحليل جين SUFU لمتلازمة الوحمة القاعدية الخلوية (جورلين) في الإمارات | 2800 درهم | هيئة الصحة بدبي
📋 Executive Summary (ملخص تنفيذي)
This NGS‑based genetic test comprehensively analyses the full SUFU gene to diagnose Nevoid Basal Cell Carcinoma Syndrome (Gorlin syndrome) with 99.9% diagnostic sensitivity at our ISO‑certified laboratory in Dubai. The service includes mandatory pre‑test genetic counselling, cold‑chain home blood collection, and post‑test telephonic clinical interpretation, fully aligned with UAE Federal Decree‑Law No. 41 of 2024.
يُعد تحليل تسلسل الجين SUFU باستخدام تقنية الجيل التالي (NGS) حجر الزاوية في تشخيص متلازمة جورلين بدقة تصل إلى 99.9%. يقدَّم الفحص بسعر 2800 درهم مع خدمة سحب الدم المنزلي المعتمدة وتوجيه سريري هاتفي ما بعد النتيجة، وفقاً للقانون الاتحادي رقم 41 لسنة 2024.
Overview
The SUFU Gene Basal Cell Nevus Syndrome NGS Test sequences the entire coding region and adjacent splice sites of the SUFU gene using Next Generation Sequencing, identifying pathogenic variants responsible for Gorlin syndrome—a multisystem disorder characterized by early‑onset basal cell carcinomas, jaw keratocysts, and medulloblastoma. A positive result enables evidence‑based surveillance and family cascade screening in paediatrics, dermatology, and oncology.
يستخدم هذا الاختبار التسلسل الكامل للجين SUFU لتأكيد متلازمة جورلين الوراثية، مما يسهم في التخطيط للفحص الدوري والوقاية المبكرة من الأورام لدى الأطفال والبالغين.
| Feature | Our Test (SUFU NGS) | Closest Alternative |
|---|---|---|
| Precision | Full gene coverage, 99.9% sensitivity | Targeted hotspot panel, ~80% mutation detection |
| Methodology | NGS with ISO‑validated bioinformatics | Sanger sequencing of selected exons |
| Turnaround Time | 3 – 4 weeks | 5 – 6 weeks |
| Clinical Utility | Comprehensive, supports cascade screening | May miss novel/private mutations |
Physician Insight & Safety Protocol
“As a paediatric geneticist, I rely on the SUFU NGS test to confirm Gorlin syndrome in children presenting with macrocephaly, palmar pits, or early basal cell carcinomas. The result must be integrated with clinical findings and family history to guide life‑saving surveillance protocols. Please never adjust treatment based solely on a genetic report without consulting your specialist.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011
⚠️ Medication Warning:
Do not discontinue prescribed medication without consulting your doctor. This genetic test does not provide pharmacogenomic advice for any ongoing dermatological or oncological treatments.
Exclusion Criteria & Red Flags
- Patients unwilling or unable to complete pre‑test genetic counselling and a three‑generation pedigree chart, as mandated by UAE clinical guidelines.
- Minors are tested only with signed parental consent and a documented clinical indication (CDS Law 2026); asymptomatic screening of minors is refused.
- Unsuitable sample: haemolyzed blood, insufficient DNA yield, or degraded FTA card may require recollection.
- ER Red Flags: Rapidly enlarging jaw cysts, acute neurological symptoms, or signs of medulloblastoma demand immediate emergency care—do not wait for genetic test results.
Patient FAQ & Clinical Guidance
Q: How accurate is the SUFU NGS test for detecting Gorlin syndrome?
A: Our SUFU NGS test achieves a diagnostic sensitivity of over 99.9% for point mutations and small insertions/deletions across the entire coding region. Rare large deletions/duplications (<1% of variants) may require confirmatory MLPA analysis, which your genetic counsellor will recommend if the family history is suggestive.
كم يستغرق وقت صدور النتيجة؟
الإجابة: يتم إصدار التقرير النهائي خلال 3 إلى 4 أسابيع من استلام العينة الصالحة في مختبرنا المعتمد وفق ISO 9001:2015. في حالات الطوارئ السريرية يمكن تسريع النتائج بعد استشارة الأخصائي الوراثي.
Q: Can I use a home collection service for this?
A: Yes, our hospital‑grade home collection service covers all UAE regions from 8 AM to 11 PM, with cold‑chain transport maintaining sample integrity. Our phlebotomist will draw a blood sample (EDTA tube) or prepare a dried blood spot (FTA card) after completing the pre‑analytical documentation.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians