Test Price
2,800 AED✅ Home Collection Available
SUFU Gene Basal Cell Nevus Syndrome (Gorlin Syndrome) NGS Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
This NGS‑based genetic test comprehensively analyses the full SUFU gene to diagnose Nevoid Basal Cell Carcinoma Syndrome (Gorlin syndrome) with 99.9% diagnostic sensitivity at our ISO‑certified laboratory in Dubai. The service includes mandatory pre‑test genetic counselling, temperature‑controlled cold‑chain home blood collection, and post‑test telephonic clinical interpretation. Results are delivered within 3–4 weeks, fully aligned with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
Test Overview & Methodology
The SUFU Gene Basal Cell Nevus Syndrome NGS Test sequences the entire coding region and adjacent splice sites of the SUFU gene using Next Generation Sequencing, identifying pathogenic variants responsible for Gorlin syndrome—a multisystem disorder characterized by early‑onset basal cell carcinomas, jaw keratocysts, and medulloblastoma. A positive result enables evidence‑based surveillance and family cascade screening in paediatrics, dermatology, and oncology.
| Feature | Our Test (SUFU NGS) | Closest Alternative |
|---|---|---|
| Precision | Full gene coverage, 99.9% sensitivity | Targeted hotspot panel, ~80% mutation detection |
| Methodology | NGS with ISO‑validated bioinformatics | Sanger sequencing of selected exons |
| Turnaround Time | 3 – 4 weeks | 5 – 6 weeks |
| Clinical Utility | Comprehensive, supports cascade screening | May miss novel or private mutations |
Physician Insight & Safety Protocols
"Comprehensive SUFU gene sequencing is the gold standard for confirming Gorlin syndrome, enabling early and life-saving surveillance for basal cell carcinomas and medulloblastoma. The genetic result must always be interpreted alongside the clinical phenotype and a detailed three-generation family pedigree. Any therapeutic or surgical decisions should be made through a multidisciplinary team approach involving the patient's primary physician and a clinical geneticist."
— Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
⚠️ Medication Advisory
Do not discontinue or alter prescribed dermatological or oncological treatments based solely on this genetic test result. All medical decisions, including the use of targeted therapies or chemoprevention, must be reviewed and approved by a qualified healthcare provider.
Exclusion Criteria & Red Flags
- Patients who have not completed mandatory pre‑test genetic counselling and a three‑generation pedigree assessment as mandated by UAE clinical guidelines.
- Minors tested without explicit parental consent and a documented clinical indication in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Unsuitable specimen: haemolyzed blood, insufficient DNA yield, or degraded FTA card may necessitate a fresh recollection.
- ER Red Flags: Acute neurological deterioration, rapidly enlarging jaw cysts, or signs suggestive of medulloblastoma require immediate emergency intervention—do not delay care while awaiting genetic test results.
Patient FAQ & Clinical Guidance
1. What is the SUFU gene test used for?
The SUFU gene NGS test is used to diagnose Nevoid Basal Cell Carcinoma Syndrome (Gorlin syndrome), a hereditary condition that predisposes individuals to multiple basal cell carcinomas, jaw keratocysts, and medulloblastoma. It analyzes the entire SUFU gene for pathogenic mutations to confirm the clinical diagnosis.
2. How accurate is the SUFU NGS genetic test?
This test achieves a diagnostic sensitivity of over 99.9% for point mutations and small insertions or deletions across the full coding region and splice sites of the SUFU gene. Rare large rearrangements, representing less than 1% of variants, may require additional MLPA analysis.
3. How is the sample collected for this genetic test?
A peripheral whole blood sample collected in an EDTA tube or a dried blood spot on an FTA card is required. DNA Labs UAE provides a VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection service, which is available daily from 8 AM to 11 PM across all UAE regions.
4. What is the cost of the SUFU gene test?
The total price for the SUFU Gene Basal Cell Nevus Syndrome NGS Genetic Test is 2,800 AED. This includes the full genetic analysis, mandatory pre-test counselling, and a post-test telephonic consultation with a genetic specialist.
5. When will I receive the results?
The final comprehensive clinical report is typically issued within 3 to 4 weeks from the receipt of a valid sample at our ISO 9001:2015 certified laboratory located in Dubai Healthcare City.
UAE Regulatory & Data Privacy Adherence
Regulatory & Data Privacy Compliance
DNA Labs UAE operates under DHA Facility License Number 1143. All genetic testing services strictly adhere to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent protocols are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genetic data is encrypted, securely stored, and processed exclusively within the UAE.
Clinical & Logistical Metadata
| Test Name | SUFU Gene Basal Cell Nevus Syndrome (Gorlin Syndrome) NGS Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3 – 4 weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) or Dried Blood Spot (FTA Card) |
| Methodology Used | Next Generation Sequencing (NGS) |
| ICD-10-CM Code | Q85.01 |
| LOINC Code | 90278-2 |
| DHA Facility License & Address | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. License No: 1143 | DNA Labs UAE |
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