Test Price
2,800 AED✅ Home Collection Available
EpCAM Gene (Lynch Syndrome Type 8) Genetic Test in UAE – 2,800 AED – DHA Licensed Facility 1143
Executive Summary & Core Metrics
Accuracy Guarantee
99.9% diagnostic sensitivity via ISO 9001:2015 accredited Next Generation Sequencing (NGS) and dual-bioinformatics pipeline verification.
Premium Logistics
VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM across all Emirates.
Clinical Guidance
Telephonic post-test clinical interpretation by a Consultant Medical Genetics, included in the test price.
Insurance & Billing
Direct insurance billing verification and pre-authorisation support via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This test sequences the entire coding region and splice sites of the EpCAM gene to detect germline mutations responsible for hereditary nonpolyposis colorectal cancer (Lynch syndrome type 8). It provides a definitive molecular diagnosis that guides intensified colonoscopic surveillance, prophylactic surgery decisions, and family cascade testing.
| Feature | Our EpCAM NGS Test | Closest Alternative (Single‑Gene Sanger) |
|---|---|---|
| Methodology | Next‑Generation Sequencing (NGS) with CNV detection and full bioinformatics verification | Sanger sequencing of selected exons only; limited copy‑number analysis |
| Analytical Sensitivity | >99.9% for single nucleotide variants and large deletions | ~95% for point mutations; may miss exonic deletions common in EPCAM |
| Turnaround Time | 14–21 business days from sample receipt | 6–10 weeks, often with multiple reflex steps |
| Clinical Report | Full ACMG/AMP classification, risk‑aligned surveillance recommendations, and family cascade plan | Binary result report, minimal interpretive guidance |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I know that receiving a genetic cancer risk result can be deeply unsettling. This test is the most accurate way to clarify whether you carry an inherited EPCAM mutation, but it must always be interpreted in the full context of your personal and family cancer history. Please do not alter any medical or surgical plan before discussing the result with your managing physician.” — Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA Registration ID: 9294403)
Advisory: Genetic Testing Guidelines
- Always complete the mandatory pre-test genetic counselling session before sample collection.
- Ensure you have a valid, witnessed informed consent form, especially for minors where guardian consent is required per UAE regulations.
- Results must be interpreted by a qualified medical professional in conjunction with your clinical history.
Exclusion Criteria & Red‑Flag Symptoms
- Age below 18 years without written consent of a legal guardian.
- Current, unstable myeloid or lymphoid malignancy that could confound germline variant calling.
- Inability to provide a valid, witnessed informed consent after the mandatory pre-test genetic counselling session.
- Emergency red flags: If you experience acute rectal bleeding, sudden severe abdominal pain, or unexplained weight loss >5% in one month, seek immediate face‑to‑face medical evaluation; do not delay for genetic test results.
- Never stop or alter any prescribed medication without explicit instruction from your treating physician.
Patient FAQ & Clinical Guidance
1. What does a positive EpCAM gene test mean for my cancer risk?
Snippet: A positive result confirms you carry a pathogenic or likely pathogenic EPCAM mutation, which elevates your lifetime risk of colorectal and other Lynch‑spectrum cancers up to 70–80%.
This does not mean you have cancer; it is a hereditary susceptibility. Immediate clinical actions include a colonoscopy every 1–2 years starting at age 20–25 and, in some cases, prophylactic surgery. A gastroenterologist or clinical oncologist will personalise the surveillance plan.
2. How is the sample collected and what preparation is needed?
Snippet: A simple blood draw (or a single drop of blood on a provided FTA card) is all that is required; no fasting or medication adjustment is recommended.
Our VIP mobile phlebotomist visits your home, office, or hotel across all Emirates. The sample is transported in an ISO‑certified cold‑chain kit to our CAP‑accredited laboratory. Before collection, you must complete a mandatory virtual genetic counselling session where a family pedigree is drawn and informed consent is obtained. No dietary restriction is needed, but please inform the team of any recent blood transfusions or allogeneic transplants.
3. Is this covered by UAE health insurance and how long for results?
Snippet: Most UAE insurers cover hereditary cancer genetic testing when pre‑authorised through the DHA eClaim portal, and your final report is delivered within 14–21 business days.
Our billing team directly verifies your policy and obtains prior approval on your behalf via WhatsApp (+971 54 548 8731). After the laboratory has received the sample, you will receive the secure, encrypted report in 14–21 business days. The report includes an English‑language interpretive summary and a risk‑stratified management letter that can be shared directly with your oncologist or gastroenterologist.
UAE Regulatory & Data Privacy Adherence
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – All genetic data is classified as sensitive personal information, stored exclusively on encrypted, on‑shore servers with zero cross‑border transfer without explicit patient authorisation.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – Ensures secure electronic health data exchange, with audit trails and patient consent for processing.
- DHA Facility License Number: 1143 – Laboratory accredited by Dubai Health Authority for high‑complexity genetic testing.
Clinical & Logistical Metadata
| Test Name | EpCAM Gene (Lynch Syndrome Type 8) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 14–21 business days from sample receipt |
| Sample Type / Matrix | Peripheral whole blood (venous draw) or dried blood spot on FTA card |
| Methodology Used | Next‑Generation Sequencing (Illumina NovaSeq X Plus) covering all coding exons ±10 bp flanking intronic regions; CNV detection via MLPA; variant classification per ACMG/AMP 2026 guidelines |
| ICD-10-CM Code | Z15.01, C18.9, Z12.11 |
| LOINC Code | 79747-6 |
| DHA Facility License & Laboratory Address Invariants | DHA License: 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (Corporate Lab: DNA Labs UAE) |
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