Test Price
2,800 AEDโ Home Collection Available
CDKN2A Gene Melanoma, Cutaneous Malignant, Familial Genetic Test โ 2,800 AED โ DNA Labs UAE
Executive Summary & Core Metrics
Advanced genetic screening using Next-Generation Sequencing (NGS) for the CDKN2A gene, offering 99.9% diagnostic sensitivity through an ISO 9001:2015 accredited laboratory. Includes VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, telephonic post-test clinical guidance, and direct billing verification via WhatsApp +971 54 548 8731. All processes comply with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The CDKN2A Genetic Test detects inherited mutations in the p16 tumor suppressor gene, providing critical risk assessment for familial atypical multiple mole melanoma (FAMMM) syndrome. Next-Generation Sequencing (NGS) with copy number variant (CNV) analysis ensures comprehensive detection of point mutations, small indels, and large deletions/duplications.
| Feature | Our NGS CDKN2A Test | Closest Alternative (Single-Gene Sanger) |
|---|---|---|
| Precision | 99.9% analytical sensitivity; detects point mutations, small indels, and copy number variants | ~98% for point mutations; may miss large deletions/duplications |
| Method | Next-Generation Sequencing with CNV analysis | Sanger sequencing, typically without dosage analysis |
| Turnaround Time | 3 โ 4 weeks | 4 โ 6 weeks (may require multiple reactions) |
Physician Insight & Safety Protocols
โGenetic testing for familial melanoma provides crucial risk information, but it must be interpreted within the full clinical context. A negative result does not eliminate risk; continued dermatological surveillance and sun protection remain essential. I encourage every patient to discuss these findings with both a genetic counselor and a dermatologist.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA License 9294403
Safety Protocol & Medication Advisory
Medication Warning
Do not discontinue prescribed medication without consulting your doctor. This test analyzes your DNA and does not interact with any drugs; however, any changes to health management must be medically supervised.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Testing without prior genetic counseling session (mandatory per UAE regulations).
- Exclusion: Inability to provide informed consent or cognitive impairment.
- Exclusion: Minors without legal guardian consent.
- Red Flag โ Seek immediate dermatology review: New or changing mole, appearance of a spot with ABCD features, or family history of pancreatic cancer (linked to CDKN2A).
- Red Flag: Unexplained skin lesion that bleeds or itches.
Patient FAQ & Clinical Guidance
1. What is the CDKN2A gene and why is it tested?
The CDKN2A gene produces the p16 tumor suppressor protein; mutations significantly increase lifetime melanoma risk up to 70%.
2. How is the test performed and what is the sample requirement?
A single blood sample (3 mL EDTA whole blood) is collected by a DHA-licensed phlebotomist during a VIP home visit. Alternatively, a dried blood spot on FTA card may be used.
3. What does a positive or negative result mean?
A positive result confirms a pathogenic variant linked to familial melanoma, guiding intensified surveillance; a negative result reduces but does not eliminate risk.
UAE Regulatory & Data Privacy Adherence
This test and home collection service fully adhere to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. Laboratory processes are certified under ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). All personal health information is encrypted and stored within UAE borders.
Clinical & Logistical Metadata
| Test Name | CDKN2A Gene Melanoma, Cutaneous Malignant, Familial Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 โ 4 weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA) or dried blood spot (FTA card) |
| Methodology Used | Next-Generation Sequencing (NGS) with CNV analysis |
| ICD-10-CM Code | Z15.01 |
| LOINC Code | 21658-0 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE Corporate Lab Branding: DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians